Dr Mark Bowles
Centre Manager & Centre Manager
Child Health Research Centre
+61 7 3069 7592
Journal Articles
Payne, Elizabeth, Bowles, Mark R., Don, Alistair, Hancock, John F. and McMillan, Nigel A. J. (2001). Human papillomavirus type 6b virus-like particles are able to activate the Ras-MAP kinase pathway and induce cell proliferation. Journal of Virology, 75 (9), 4150-4157. doi: 10.1128/JVI.75.9.4150-4157.2001
Bowles, M. R., Mulhern, T. D., Gordon, R. B., Inglis, H. R., Sharpe, I. A., Cogill, J. L. and Pond, S. M. (1997). Bound Tris confounds the identification of binding site residues in a paraquat single chain antibody. Journal of Biochemistry, 122 (1), 101-108. doi: 10.1093/oxfordjournals.jbchem.a021716
Bowles, Mark R., Hall, Damien R., Pond, Susan M. and Winzor, Donald J. (1997). Studies of protein interactions by biosensor technology: an alternative approach to the analysis of sensorgrams deviating from pseudo-first-order kinetic behavior. Analytical Biochemistry, 244 (1), 133-143. doi: 10.1006/abio.1996.9888
Bowles M.R., King G.J., Berndt M.C. and Zerner B. (1996). New catalytic roles for serine esterases: A 19F-NMR study of the interaction of 3,3,3-trifluoro-2,2-dihydroxy-1-phenyl-1-propanone with chicken liver carboxylesterase. Biochimica et Biophysica Acta - Protein Structure and Molecular Enzymology, 1298 (2), 167-179. doi: 10.1016/S0167-4838(96)00116-1
Berndt, M. C., Bowles, M. R., King, G. J. and Zerner, B. (1996). Inhibition of chicken liver carboxylesterase by activated carbonyls and carbonyl hydrates. Biochimica et Biophysica Acta - Protein Structure and Molecular Enzymology, 1298 (2), 159-166. doi: 10.1016/S0167-4838(96)00117-3
Rivory, Laurent P., Bowles, Mark R., Robert, Jacques and Pond, Susan M. (1996). Conversion of irinotecan (CPT-11) to its active metabolite, 7-ethyl-10-hydroxycamptothecin (SN-38) by human liver carboxylesterase. Biochemical Pharmacology, 52 (7), 1103-1111. doi: 10.1016/0006-2952(96)00457-1
Devlin, Cecilia M., Bowles, Mark R., Gordon, Ross B. and Pond, Susan M. (1995). Production of a paraquat-specific murine single chain Fv fragment. Journal of Biochemistry, 118 (3), 480-487. doi: 10.1093/oxfordjournals.jbchem.a124933
Chen N., Bowles M.R. and Pond S.M. (1994). Prevention of Paraquat Toxicity in Suspensions of Alveolar Type II Cells by Paraquat-Specific Antibodies. Human & Experimental Toxicology, 13 (8), 551-557. doi: 10.1177/096032719401300808
Bowles, Mark R., Eyles, Darryl W., Hampson, Edith C. G. M. and Pond, Susan M. (1992). Quantitation of paraquat in biological samples by radioimmunoassay using a monoclonal antibody. Toxicological Sciences, 19 (3), 375-379. doi: 10.1093/toxsci/19.3.375
Bowles, MR, Eyles, DW, Hampson, Ecgm and Pond, SM (1992). Quantitation of Paraquat in Biological Samples by Radioimmunoassay Using a Monoclonal-Antibody. Fundamental and Applied Toxicology, 19 (3), 375-379. doi: 10.1016/0272-0590(92)90176-I
Chen, Nian, Bowles, Mark R. and Pond, Susan M. (1992). Competition between paraquat and putrescine for uptake by suspensions of rat alveolar type II cells. Biochemical Pharmacology, 44 (6), 1029-1036. doi: 10.1016/0006-2952(92)90364-O
Riddles P.W., Richards L.J., Bowles M.R. and Pond S.M. (1991). Cloning and analysis of a cDNA encoding a human liver carboxylesterase. Gene, 108 (2), 289-292. doi: 10.1016/0378-1119(91)90448-K
Winzor, Donald J., Bowles, Mark R., Pentel, Paul R., Schoof, Deric D. and Pond, Susan M. (1991). Adaptation of the Müller method to allow quantitative characterization of the affinity and cross-reactivity of antibodies by competitive radioimmunoassay. Molecular Immunology, 28 (9), 995-1001. doi: 10.1016/0161-5890(91)90185-M
Grimes, D. J., Bowles, M. R., Buttsworth, J. A., Thomson, D. B., Ravenscroft, P. J., Nixon, P. F., Whiting, R. F. and Pond, S. M. (1990). Survival after unexpected high serum methotrexate concentrations in a patient with osteogenic-sarcoma. Drug Safety, 5 (6), 447-454. doi: 10.2165/00002018-199005060-00005
Bowles M.R. and Pond S.M. (1990). The importance of electrostatic interactions in the binding of paraquat to its elicited monoclonal antibody. Molecular Immunology, 27 (9), 847-852. doi: 10.1016/0161-5890(90)90150-X
Ketterman, A. J., Bowles, M. R. and Pond, S. M. (1989). Purification and characterization of two human liver carboxylesterases. International Journal of Biochemistry, 21 (12), 1303-1312. doi: 10.1016/0020-711X(89)90149-3
Johnston, Shane C., Bowles, Mark, Winzor, Donald J. and Pond, Susan M. (1988). Comparison of paraquat-specific murine monoclonal antibodies produced by in vitro and in vivo immunization. Fundamental and Applied Toxicology, 11 (2), 261-267. doi: 10.1016/0272-0590(88)90150-9
Bowles, Mark, Johnston, Shane C., Schoof, Deric D., Pentel, Paul R. and Pond, Susan M. (1988). Large scale production and purification of paraquat and desipramine monoclonal antibodies and their fab fragments. International Journal of Immunopharmacology, 10 (5), 537-545. doi: 10.1016/0192-0561(88)90071-9
Pond, S. M., Johnston, S. C., Schoof, D. D., Hampson, E. C., Bowles, M., Wright, D. M. and Petrie, J. J. (1987). Repeated hemoperfusion and continuous arteriovenous hemofiltration in a paraquat poisoned patient. Journal of Toxicology-Clinical Toxicology, 25 (4), 305-316. doi: 10.3109/15563658708992634
Hogg, Philip J., Johnston, Shane C., Bowles, Mark R., Pond, Susan M. and Winzor, Donald J. (1987). Evaluation of equilibrium constants for antigen-antibody interactions by solid-phase immunoassay: the binding of paraquat to its elicited mouse monoclonal antibody. Molecular Immunology, 24 (7), 797-801. doi: 10.1016/0161-5890(87)90064-2
Conference Paper
Pond, S. M., Bowles, M. R., Johnston, S. C., Hampson, E. C., Wright, D. M. and Petrie, J. J. (1986). Continuous arteriovenous hemofiltration for paraquat poisoning. Unknown, Unknown, Unknown. Manhattan, KS USA: Comparative Toxicology Laboratories.