Dr Trish Gilholm
Research Fellow/Senior Research officer
Child Health Research Centre
Researcher biography
Dr Trish Gilholm is a Research Fellow (3.5 years post‑PhD) within the Children's Intensive Care Research Program, Child Health Research Centre. Her emerging research programs explore 1) long‑term outcomes for critically ill children using data linkage and 2) adaptive trial designs in paediatric critical care. Dr Gilholmcompleted her PhD in statistics at the Australian Centre of Excellence in Mathematical and Statistical Frontiers, Queensland University of Technology (PhD conferral September 2021) and was awarded an Executive Dean Commendation for Outstanding Doctoral Thesis Award for her PhD thesis. Through her developing research programs in adaptive trial design and data linkage, she has established a unique research profile within paediatric critical care. She is currently supervising 1xHonours (Principal Advisor), 1xPhD (Associate Advisor) and regularly supervises undergraduate and medical school research projects. Her outstanding commitment to research and future potential as a researcher was recognised with the 2024 Child Health Research Centre Rising Star of the Year Award.
Journal Articles
Irwin, Adam D., Graham, Nicolette, Gartrell, Kyana, Fletchett, Emily, Cross, Jack, Doyle, Kayla, Owen, Kieran, Seaton, Robert, Rice, Michael, Lane, Paul, Ergetu, Endrias, Gilholm, Patricia, Gibbons, Kristen S., Raman, Sainath, Harley, Amanda, Lister, Paula, Grimwood, Keith, Schlapbach, Luregn J., on behalf of the Queensland Statewide Sepsis Collaborative, Redpath, Lyndell, Mason, Donna, Kalke, Vikrant, Mehta, Naitik, Taylor, Scott and Bell, Anna (2025). Impact of a statewide sepsis pathway on quality of antibiotic use in children in the Emergency Department. Intensive Care Medicine – Paediatric and Neonatal, 3 (1) 11, 1-10. doi: 10.1007/s44253-025-00060-x
Gilholm, Patricia, Raman, Sainath, Irwin, Adam, Lister, Paula, Harley, Amanda, Schlapbach, Luregn J. and Gibbons, Kristen S. (2025). Identification of distinct clinical profiles of sepsis risk in paediatric emergency department patients using Bayesian profile regression. BMJ Paediatrics Open, 9 (1) e003100, e003100-1. doi: 10.1136/bmjpo-2024-003100
Gilholm, Patricia, Lister, Paula, Irwin, Adam, Harley, Amanda, Raman, Sainath, Schlapbach, Luregn J. and Gibbons, Kristen S. (2025). Comparison of Random Forest and Stepwise Regression for Variable Selection Using Low Prevalence Predictors: A case Study in Paediatric Sepsis. Maternal and Child Health Journal, 1-10. doi: 10.1007/s10995-025-04038-1
Gilholm, Patricia, Wu, Ken, Le Marsney, Renate and Gibbons, Kristen (2024). Barriers and facilitators to implementing adaptive trial designs in paediatric critical care: an international mixed-methods study. Intensive Care Medicine - Paediatric and Neonatal, 2 (1) 31. doi: 10.1007/s44253-024-00054-1
Le Marsney, Renate, Johnson, Kerry, Chumbes Flores, Jenipher, Coetzer, Shelley, Darvas, Jennifer, Delzoppo, Carmel, Jolly, Arielle, Masterson, Kate, Sherring, Claire, Thomson, Hannah, Ergetu, Endrias, Gilholm, Patricia and Gibbons, Kristen S. (2024). Assessing the impact of risk-based data monitoring on outcomes for a paediatric multicentre randomised controlled trial. Clinical Trials, 21 (4), 461-469. doi: 10.1177/17407745231222019
Long, Debbie A., Gilholm, Patricia, Le Brocque, Robyne, Kenardy, Justin, Gibbons, Kristen and Dow, Belinda L. (2024). Post-traumatic stress and health-related quality of life after admission to paediatric intensive care: Longitudinal associations in mother–child dyads. Australian Critical Care, 37 (1), 98-105. doi: 10.1016/j.aucc.2023.10.004
Gilholm, Patricia, Ergetu, Endrias, Gelbart, Ben, Raman, Sainath, Festa, Marino, Schlapbach, Luregn J., Long, Debbie, Gibbons, Kristen S. and on behalf of the Australian and New Zealand Intensive Care Society Paediatric Study Group (2023). Adaptive clinical trials in pediatric critical care: a systematic review. Pediatric Critical Care Medicine, 24 (9), 738-749. doi: 10.1097/pcc.0000000000003273
Gilholm, Patricia, Gibbons, Kristen, Brüningk, Sarah, Klatt, Juliane, Vaithianathan, Rhema, Long, Debbie, Millar, Johnny, Tomaszewski, Wojtek, Schlapbach, Luregn J., Ganeshalingam, Anusha, Sherring, Claire, Erickson, Simon, Barr, Samantha, Raman, Sainath, Long, Debbie, Schlapbach, Luregn, Gibbons, Kristen, George, Shane, Singh, Puneet, Smith, Vicky, Butt, Warwick, Delzoppo, Carmel, Millar, Johnny, Gelbart, Ben, Oberender, Felix, Ganu, Subodh, Letton, Georgia, Festa, Marino, Harper, Gail and the Australian and New Zealand Intensive Care Society (ANZICS) Centre for Outcomes & Resource Evaluation (CORE) and ANZICS Paediatric Study Group (ANZICS PSG) (2023). Machine learning to predict poor school performance in paediatric survivors of intensive care: a population-based cohort study. Intensive Care Medicine, 49 (7), 785-795. doi: 10.1007/s00134-023-07137-1
Sever, Zoe, Schlapbach, Luregn J., Gilholm, Patricia, Jessup, Melanie, Phillips, Natalie, George, Shane, Gibbons, Kristen and Harley, Amanda (2023). Impact of parental and healthcare professional concern on the diagnosis of pediatric sepsis: a diagnostic accuracy study. Frontiers in Pediatrics, 11 1140121, 1140121. doi: 10.3389/fped.2023.1140121
Gilholm, Patricia, Gibbons, Kristen, Lister, Paula, Harley, Amanda, Irwin, Adam, Raman, Sainath, Rice, Michael, Schlapbach, Luregn J. and Queensland Statewide Sepsis Collaborative (2023). Validation of a paediatric sepsis screening tool to identify children with sepsis in the emergency department: a statewide prospective cohort study in Queensland, Australia. BMJ Open, 13 (1) e061431, 1-25. doi: 10.1136/bmjopen-2022-061431
Morin, Luc, Hall, Mark, de Souza, Daniela, Guoping, Lu, Jabornisky, Roberto, Shime, Nobuaki, Ranjit, Suchitra, Gilholm, Patricia, Nakagawa, Satoshi, Zimmerman, Jerry J., Sorce, Lauren R., Argent, Andrew, Kissoon, Niranjan, Tissières, Pierre, Watson, R. Scott and Schlapbach, Luregn J (2022). The current and future state of pediatric sepsis definitions: an international survey. Pediatrics, 149 (6) e2021052565. doi: 10.1542/peds.2021-052565
Harley, Amanda, Lister, Paula, Gilholm, Patricia, Rice, Michael, Venkatesh, Bala, Johnston, Amy N.B., Massey, Debbie, Irwin, Adam, Gibbons, Kristen and Schlapbach, Luregn J. (2021). Queensland Pediatric Sepsis Breakthrough Collaborative: Multicenter Observational Study to Evaluate the Implementation of a Pediatric Sepsis Pathway Within the Emergency Department. Critical Care Explorations, 3 (11) e0573, 1-14. doi: 10.1097/cce.0000000000000573
Harley, Amanda, Schlapbach, Luregn J., Lister, Paula, Massey, Debbie, Gilholm, Patricia and Johnston, Amy N. B. (2021). Knowledge translation following the implementation of a state-wide Paediatric Sepsis Pathway in the emergency department- a multi-centre survey study. BMC Health Services Research, 21 (1) 1161, 1161. doi: 10.1186/s12913-021-07128-2
Gilholm, Patricia, Mengersen, Kerrie and Thompson, Helen (2021). Bayesian hierarchical multidimensional item response modeling of small sample, sparse data for personalized developmental surveillance. Educational and Psychological Measurement, 81 (5) 0013164420987582, 936-956. doi: 10.1177/0013164420987582
Gilholm, Patricia, Mengersen, Kerrie and Thompson, Helen (2020). Identifying latent subgroups of children with developmental delay using Bayesian sequential updating and Dirichlet process mixture modelling. PLoS One, 15 (6) e0233542, 1-17. doi: 10.1371/journal.pone.0233542
Vermande, Marjolijn M., Gilholm, Patricia A., Reijntjes, Albert H. A., Hessen, Dave J., Sterck, Elisabeth H. M. and Overduin-de Vries, Anne M. (2018). Is inspiring group members an effective predictor of social dominance in early adolescence? direct and moderated effects of behavioral strategies, social skills, and gender on resource control and popularity. Journal of Youth and Adolescence, 47 (9), 1813-1829. doi: 10.1007/s10964-018-0830-9
Conference Paper
Gilholm, P., Irwin, A., Lister, P., Harley, A., Raman, S., Schlapbach, L. J. and Gibbons, K. (2022). Identifying clinical symptom profiles for sepsis in children screened for sepsis on admission to the emergency department. 11th Congress of the World Federation of Pediatric Intensive & Critical Care Societies, Online, 12-16 July 2022. Philadelphia, PA United States: Lippincott Williams & Wilkins. doi: 10.1097/01.pcc.0000899876.46317.ec