Honorary Professor Christel Middeldorp
Professor, Honorary
Child Health Research Centre
Professor Christel Middeldorp has a conjoint appointment with the Child Health Research Centre (CHRC), UQ, and Child and Youth Mental Health Service (CYMHS), Children’s Health Queensland Hospital and Health Service (CHQ HHS). Her research interests involve the role of genetic and other familial influences on the development and persistence of psychopathology across the lifespan. She is the co-PI of the Behavior&Cognition working group of the EAGLE consortium (EArly Genetics and Lifecourse Epidemiology). EAGLE aims to identify genetic variants underlying the development and persistence of childhood psychopathology by using data from population based longitudinal child and adolescent cohorts from over the world. She further investigates associations between parental and offspring psychopathology and the development of these associations over time in a clinical cohort consisting of families with children treated at outpatient psychiatric services, who are followed longitudinally.
Qualifications
MD (Rotterdam, The Netherlands), PhD (Amsterdam, The Netherlands), Child and adolescent psychiatrist (Amsterdam, The Netherlands)
Research Support
Ongoing
2021-2026: PRE-EMPT: Prediction of Early Mental Disorder and Preventive Treatment - Centre of Research Excellence. NHMRC Centre of Research Excellence, Aus$2.5M, Role Chief Investigator (CI)-F.
2020-2024: Does repetitive transcranial magnetic stimulation (rTMS), compared to sham rTMS, improve social communication in adolescents and young adults with autism Spectrum Disorder (ASD). Medical Research Future Fund – Unmet needs. AUS$1.9M. Role CI-G
2020-2023: Child & Adolescent Victimisation: prevalence and predictors in Australia. ARC Discovery Project, DP200102159, Aus$500k, Role CI-G
2019-2021: Children with ADHD in Child & Youth Mental Health services. Governmental funding for the Australian ADHD Professional Association (AADPA), Aus$150k
Completed
2017-2021 CAPICE: Childhood and Adolescence Psychopathology: unravelling the complex etiology by a large Interdisciplinary Collaboration in Europe. EU Marie Curie European Training Network €3,100,000.
2011-2017 Genetic influences on stability and change in psychopathology from childhood to young adulthood. The Netherlands Organization for Health Research and Development (ZonMw-TOP 91210020).
2007-2012 The interplay of genetic and environmental factors in the development of anxious depression in children and adults. The Netherlands Organization for Health Research and Development (ZonMw) – Innovational Research Incentives scheme –VENI grant (91676125), €208.000,-. Role: PI.
2009-2011 Psychopathology in parents of children with a psychiatric disorder. The Netherlands. Foundation for Mental Health (Fonds Psychische Gezondheid 20096398), € 50,000. Role: PI.
Awards
2018 Children’s Health Queensland Research Excellence Award.
2017 AACAP’s Ülkü Ülgür, MD, International Scholar Award. This award from the American Academy of Child and Adolescent Psychiatry (AACAP) is established by dr Ülgür in order to honor international child and adolescent psychiatrists who have significantly enhanced mental health services for children and adolescents around the world.
2012 EPA Research Prize in the category: “Clinical psychopathology and refinement of psychiatric diagnostic categories”. The prize is awarded by the European Psychiatric Association (EPA) for the best article of 2011 written by an early career psychiatrist.
2012 Fuller & Scott Early Career award, Behavior Genetics Association
Supervision of PhD students
Completed:
- Risk factors for childhood problem behavior. Studies in twins and triplets.
- Keeping focus. A study on attention problems in the gwas era.
- Developmental genetics of psychopathology
- Risk factors for the development and outcome of childhood psychopathology
- Polygenic analyses of mental health comorbidity during childhood
Current:
- (Epi)genetic factors in anxiety and traumatic stress related symptoms.
- Polygenic analyses of childhood and adolescent internalizing problems.
- Enhanced Stepping stones Triple P for parents with mental health issues
Book Chapters
Nivard, Michel, Dolan, Conor V., Middeldorp, Christel M. and Boomsma, Dorret I. (2016). Behavior genetics: From heritability to gene finding. Handbook of Psychophysiology. (pp. 339-353) Cambridge, United Kingdom: Cambridge University Press. doi: 10.1017/9781107415782.015
van Dyck, Richard, van Balkom, Anton J.L.M., van den Heuvel, Odile A. and Middeldorp, Christel M. (2014). Psychiatric perspective. The Wiley handbook of anxiety disorders. (pp. 1371-1381) edited by Paul Emmelkamp and Thomas Ehring. Chichester, West Sussex, United Kingdom: John Wiley & Sons. doi: 10.1002/9781118775349.ch67
Middeldorp, Christel M. and Boomsma, Dorret I. (2009). Genetics and Psychopathology. Handbook of neuroscience for the behavioral sciences. (pp. 1180-1202) edited by Gary G. Berntson and John T. Cacioppo. New York, NY, United States: Wiley. doi: 10.1002/9780470478509.neubb002060
Middeldorp, Christel M., Cath, Danielle C., van den Berg, Mireille, Beem, A. Leo, van Dyck, Richard and Boomsma, Dorret I. (2006). The association of personality with anxious and depressive psychopathology. The biology of personality and individual differences. (pp. 251-272) edited by Turhan Canli. New York, NY, United States: Guilford Press.
Journal Articles
Verhoef, Ellen, Allegrini, Andrea G., Jansen, Philip R., Lange, Katherine, Wang, Carol A., Morgan, Angela T., Ahluwalia, Tarunveer S., Symeonides, Christos, Andreassen, Ole A., Bartels, Meike, Boomsma, Dorret, Dale, Philip S., Ehli, Erik, Fernandez-Orth, Dietmar, Guxens, Mònica, Hakulinen, Christian, Harris, Kathleen Mullan, Haworth, Simon, de Hoyos, Lucía, Jaddoe, Vincent, Keltikangas-Järvinen, Liisa, Lehtimäki, Terho, Middeldorp, Christel, Min, Josine L., Mishra, Pashupati P., Njølstad, Pål Rasmus, Sunyer, Jordi, Tate, Ashley E., Timpson, Nicholas ... St. Pourcain, Beate (2024). Genome-Wide Analyses of Vocabulary Size in Infancy and Toddlerhood: Associations With Attention-Deficit/Hyperactivity Disorder, Literacy, and Cognition-Related Traits. Biological Psychiatry, 95 (9), 859-869. doi: 10.1016/j.biopsych.2023.11.025
Alnor, A., Besterman, A. D., Castaño, M., DeLisi, L., Grice, D. E., Lohof, F. W., Middeldorp, C., Moreno-De-Luca, D., Quattrone, D., Nurnberger, J. I., Nurmi, E., Ross, D. A., Soda, T., Schulze, T. G., Trost, B., Vilella, E., Yap, C. and Zai, G. (2024). Genetics for mental health clinicians: a call for a globally accessible and equitable psychiatric genetics education. World Psychiatry, 23 (1), 161-163. doi: 10.1002/wps.21173
Novins, Douglas K., Althoff, Robert R., Brotman, Melissa A., DelBello, Melissa P., Doyle, Alysa E., Fortuna, Lisa R., Fristad, Mary A., Middeldorp, Christel M., Njoroge, Wanjiku F. M., Rogers, Cynthia E. and Singh, Manpreet Kaur (2024). Interrogating the ways we think about children and how we conceptualize and contextualize prevention interventions in child mental health. Journal of the American Academy of Child and Adolescent Psychiatry, 63 (1), 3-4.
Novins, Douglas K., Althoff, Robert R., Brotman, Melissa A., DelBello, Melissa P., Doyle, Alysa E., Fortuna, Lisa R., Fristad, Mary A., Middeldorp, Christel M., Njoroge, Wanjikũ F.M., Rogers, Cynthia E. and Singh, Manpreet Kaur (2024). Editors’ Best of 2023. Journal of the American Academy of Child and Adolescent Psychiatry, 63 (1), 3-6. doi: 10.1016/j.jaac.2023.10.001
Novins, Douglas K., Singh, Manpreet K., Althoff, Robert R., Bagot, Kara S., Brotman, Melissa A., DelBello, Melissa P., Dickstein, Daniel P., Doyle, Alysa E., Drury, Stacy S., Findling, Robert L., Fortuna, Lisa R., Fristad, Mary A., Middeldorp, Christel M., Njoroge, Wanjikũ F.M., Rogers, Cynthia E., Pumariega, Andrés J., Bath, Eraka, Tobón, Amalia Londoño, Thompson-Felix, Tara and Billingsley, Mary K. (2023). Editors’ Note: Third Annual Report Regarding JAACAP's Antiracist Journey. Journal of the American Academy of Child and Adolescent Psychiatry, 62 (12), 1287-1294. doi: 10.1016/j.jaac.2023.09.531
Kiewa, Jacqueline, Mortlock, Sally, Meltzer-Brody, Samantha, Middeldorp, Christel, Wray, Naomi R. and Byrne, Enda M. (2023). A Common Genetic Factor Underlies Genetic Risk for Gynaecological and Reproductive Disorders and Is Correlated with Risk to Depression. Neuroendocrinology, 113 (10), 1059-1075. doi: 10.1159/000533413
Tennakoon, Gayani, Byrne, Enda M., Vaithianathan, Rhema and Middeldorp, Christel M. (2023). Using electronic health record data to predict future self‐harm or suicidal ideation in young people treated by child and youth mental health services. Suicide and Life-Threatening Behavior, 53 (5), 853-869. doi: 10.1111/sltb.12988
Bisset, Matthew, Brown, Louise E., Bhide, Sampada, Patel, Pooja, Zendarski, Nardia, Coghill, David, Payne, Leanne, Bellgrove, Mark A., Middeldorp, Christel M. and Sciberras, Emma (2023). Practitioner Review: It's time to bridge the gap – understanding the unmet needs of consumers with attention‐deficit/hyperactivity disorder – a systematic review and recommendations. Journal of Child Psychology and Psychiatry, 64 (6), 848-858. doi: 10.1111/jcpp.13752
Summerton, Ainsley, Bellows, Susannah T., Westrupp, Elizabeth M., Stokes, Mark A., Coghill, David, Bellgrove, Mark A., Hutchinson, Delyse, Becker, Stephen P., Melvin, Glenn, Quach, Jon, Efron, Daryl, Stringaris, Argyris, Middeldorp, Christel M., Banaschewski, Tobias and Sciberras, Emma (2023). Longitudinal associations between COVID-19 stress and the mental health of children with ADHD. Journal of Attention Disorders, 27 (10), 1065-1074. doi: 10.1177/10870547231168334
Lim, Jacqueline, White, Jacinda, Withington, Tania, Catania, Salvatore, Wilson, Daniel, Knight, Penny, Rees, Bronwyn, Middeldorp, Christel and Krishnamoorthy, Govind (2023). Family-based treatment takes longer for adolescents with mental health comorbidities: findings from a community mental health service. Eating Disorders, 31 (6), 588-609. doi: 10.1080/10640266.2023.2201995
Payne, Leanne, Goijen, Hedwig J., Cobham, Vanessa, Bor, William, Stathis, Stephen S., Coghill, David C. and Middeldorp, Christel M. (2023). The impact of
COVID
‐19 on children and adolescents attending Child and Youth Mental Health Services in Queensland, Australia. Early Intervention in Psychiatry, 17 (12), 1180-1188. doi: 10.1111/eip.13421
Jami, Eshim S., Hammerschlag, Anke R., Sallis, Hannah M., Qiao, Zhen, Andreassen, Ole A., Magnus, Per M., Njølstad, Pål R., Havdahl, Alexandra, Pingault, Jean-Baptiste, Evans, David M., Munafò, Marcus R., Ystrom, Eivind, Bartels, Meike and Middeldorp, Christel (2023). Do environmental effects indexed by parental genetic variation influence common psychiatric symptoms in childhood?. Translational Psychiatry, 13 (1) 94, 1-6. doi: 10.1038/s41398-023-02348-y
Thorp, Jackson G., Gerring, Zachary F., Colodro-Conde, Lucía, Byrne, Enda M., Medland, Sarah E., Middeldorp, Christel M. and Derks, Eske M. (2023). The association between trauma exposure, polygenic risk and individual depression symptoms. Psychiatry Research, 321 115101, 1-8. doi: 10.1016/j.psychres.2023.115101
Middeldorp, Christel M. (2023). Little Donkey. Journal of the American Academy of Child and Adolescent Psychiatry, 62 (3), 361-361. doi: 10.1016/j.jaac.2022.12.021
Bartels, Meike and Middeldorp, Christel M. (2023). The Association of Childhood Maltreatment and Mental Health Problems: Partly Causal and Partly Due to Other Factors. The American journal of psychiatry, 180 (2), 105-107. doi: 10.1176/appi.ajp.20220969
Tedja, Amy M., Shanmugam, Meenakshi S., Stathis, Stephen and Middeldorp, Christel M. (2023). Short research article:
COVID
‐19 and its impact on child and youth mental health service demand in the community and emergency department. Child and Adolescent Mental Health, 28 (1), 167-171. doi: 10.1111/camh.12593
Novins, Douglas K., Althoff, Robert R., Brotman, Melissa A., Cortese, Samuele, DelBello, Melissa, Doyle, Alysa, Drury, Stacy S., Fortuna, Lisa, Frazier, Jean A., Fristad, Mary, Henderson, Schuyler W., McCauley, Elizabeth, Middeldorp, Christel, Njoroge, Wanjikũ F.M., Rogers, Cynthia E. and White, Tonya (2023). Editors’ Best of 2022. Journal of the American Academy of Child & Adolescent Psychiatry, 62 (1), 1-7. doi: 10.1016/j.jaac.2022.10.002
Lu, Zhen Qi, Geus, Hanna, Roest, Sanna, Payne, Leanne, Krishnamoorthy, Govind, Littlewood, Robyn, Hoyland, Margaret, Stathis, Stephen, Bor, William and Middeldorp, Christel M. (2022). Characteristics and treatment outcomes of children and adolescents accessing treatment in Child and Youth Mental Health Services. Early Intervention in Psychiatry, 16 (12), 1297-1308. doi: 10.1111/eip.13275
Eadie, Kathryn, Galloway, Hannah and Middeldorp, Christel M. (2022). Comparisons of outcomes between different age groups attending a specialist mental health service for children and young people in care. Developmental Child Welfare, 4 (4), 288-306. doi: 10.1177/25161032221128614
Tate, Ashley E., Akingbuwa, Wonuola A., Karlsson, Robert, Hottenga, Jouke-Jan, Pool, René, Boman, Magnus, Larsson, Henrik, Lundström, Sebastian, Lichtenstein, Paul, Middeldorp, Christel M., Bartels, Meike and Kuja-Halkola, Ralf (2022). A genetically informed prediction model for suicidal and aggressive behaviour in teens. Translational Psychiatry, 12 (1) 488, 1-9. doi: 10.1038/s41398-022-02245-w
Akingbuwa, Wonuola A., Hammerschlag, Anke R., Allegrini, Andrea G., Sallis, Hannah, Kuja‐Halkola, Ralf, Rimfeld, Kaili, Lichtenstein, Paul, Lundstrom, Sebastian, Munafò, Marcus R., Plomin, Robert, Nivard, Michel G., Bartels, Meike and Middeldorp, Christel M. (2022). Multivariate analyses of molecular genetic associations between childhood psychopathology and adult mood disorders and related traits. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 192 (1-2), 3-12. doi: 10.1002/ajmg.b.32922
Sullivan, Daniel P, Payne, Leanne, Boulton, Kelsie A, Silove, Natalie, Bellgrove, Mark A, Sciberras, Emma, Coghill, David R, Guastella, Adam J and Middeldorp, Christel M (2022). Examining the pharmacological and psychological treatment of child and adolescent ADHD in Australia: Protocol for a retrospective cohort study using linked national registry data. BMJ Open, 12 (11) e064920, 1-9. doi: 10.1136/bmjopen-2022-064920
Najman, Jackob M., Clavarino, Alexandra M., McGee, Tara R., Middeldorp, Christel M., Williams, Gail M. and Scott, James G. (2022). Do adversities experienced over the early life course predict mental illness and substance use behaviour in adulthood: a birth cohort study. Journal of Psychiatric Research, 155, 542-549. doi: 10.1016/j.jpsychires.2022.09.020
Middeldorp, Christel M. (2022). One mental health problem influencing the risk for another, within individuals and between siblings. Commentary on Allegrini et al. (2022). JCPP Advances, 2 (3), e12102. doi: 10.1002/jcv2.12102
Neumann, Alexander, Nolte, Ilja M., Pappa, Irene, Ahluwalia, Tarunveer S., Pettersson, Erik, Rodriguez, Alina, Whitehouse, Andrew, van Beijsterveldt, Catharina E. M., Benyamin, Beben, Hammerschlag, Anke R., Helmer, Quinta, Karhunen, Ville, Krapohl, Eva, Lu, Yi, van der Most, Peter J., Palviainen, Teemu, St Pourcain, Beate, Seppälä, Ilkka, Suarez, Anna, Vilor-Tejedor, Natalia, Tiesler, Carla M. T., Wang, Carol, Wills, Amanda, Zhou, Ang, Alemany, Silvia, Bisgaard, Hans, Bønnelykke, Klaus, Davies, Gareth E., Hakulinen, Christian ... Tiemeier, Henning (2022). A genome-wide association study of total child psychiatric problems scores. PLoS One, 17 (8) e0273116, 1-23. doi: 10.1371/journal.pone.0273116
Payne, Leanne, Roest, Sanna L., Lu, Zhen Qi, Zendarski, Nardia, Bisset, Matthew, Sciberras, Emma, Stathis, Stephen, Siebelink, Bart M., Vermeiren, Robert R. J. M., Bellgrove, Mark A., Coghill, David and Middeldorp, Christel M. (2022). Comparing treatment outcomes in children and adolescents with ADHD to other disorders within an Australian and Dutch outpatient cohort. Journal of Attention Disorders, 26 (14), 108705472211129-1924. doi: 10.1177/10870547221112941
Jami, Eshim S., Hammerschlag, Anke R., Ip, Hill F., Allegrini, Andrea G., Benyamin, Beben, Border, Richard, Diemer, Elizabeth W., Jiang, Chang, Karhunen, Ville, Lu, Yi, Lu, Qing, Mallard, Travis T., Mishra, Pashupati P., Nolte, Ilja M., Palviainen, Teemu, Peterson, Roseann E., Sallis, Hannah M., Shabalin, Andrey A., Tate, Ashley E., Thiering, Elisabeth, Vilor-Tejedor, Natàlia, Wang, Carol, Zhou, Ang, Adkins, Daniel E., Alemany, Silvia, Ask, Helga, Chen, Qi, Corley, Robin P., Ehli, Erik A. ... Middeldorp, Christel M. (2022). Genome-wide association meta-analysis of childhood and adolescent internalizing symptoms. Journal of the American Academy of Child & Adolescent Psychiatry, 61 (7), 934-945. doi: 10.1016/j.jaac.2021.11.035
Akingbuwa, Wonuola A., Hammerschlag, Anke R., Bartels, Meike, Nivard, Michel G. and Middeldorp, Christel M. (2022). Ultra-rare and common genetic variant analysis converge to implicate negative selection and neuronal processes in the aetiology of schizophrenia. Molecular Psychiatry, 27 (9), 1-9. doi: 10.1038/s41380-022-01621-8
Roest, S. L., Siebelink, B. M., van Ewijk, H., Vermeiren, R. R.J.M., Middeldorp, C. M. and van der Lans, R. M. (2022). Sociodemographic and clinical characteristics in child and youth mental health; comparison of routine outcome measurements of an Australian and Dutch outpatient cohort - ADDENDUM. Epidemiology and Psychiatric Sciences, 31 e38, 1-1. doi: 10.1017/S2045796022000221
Middeldorp, Christel M., Akingbuwa, Wonuola A., Jami, Eshim S. and Bartels, Meike (2022). Genetisch onderzoek in de kinder- en jeugdpsychiatrie. Tijdschrift voor Psychiatrie, 64 (2022-5), 298-303.
Pain, Oliver, Hodgson, Karen, Trubetskoy, Vassily, Ripke, Stephan, Marshe, Victoria S., Adams, Mark J., Byrne, Enda M., Campos, Adrian I., Carrillo-Roa, Tania, Cattaneo, Annamaria, Als, Thomas D., Souery, Daniel, Dernovsek, Mojca Z., Fabbri, Chiara, Hayward, Caroline, Henigsberg, Neven, Hauser, Joanna, Kennedy, James L., Lenze, Eric J., Lewis, Glyn, Müller, Daniel J., Martin, Nicholas G., Mulsant, Benoit H., Mors, Ole, Perroud, Nader, Porteous, David J., Rentería, Miguel E., Reynolds, Charles F., Rietschel, Marcella ... Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium (2022). Identifying the Common Genetic Basis of Antidepressant Response. Biological Psychiatry Global Open Science, 2 (2), 115-126. doi: 10.1016/j.bpsgos.2021.07.008
Middeldorp, C. M., Akingbuwa, W. A., Jami, E. S. and Bartels, M. (2022). Genetisch onderzoek in de kinder- en jeugdpsychiatrie. Tijdschrift voor psychiatrie, 64 (5), 295-300.
Offermans, Julia E., de Bruin, Esther I., Lange, Aurelie M. C., Middeldorp, Christel M., Wesseldijk, Laura W., Boomsma, Dorret I., Dieleman, Gwen C., Bögels, Susan M. and van Steensel, Francisca J. A. (2022). The development and validation of a subscale for the school-age Child Behavior CheckList to screen for autism spectrum disorder. Journal of Autism and Developmental Disorders, 53 (3), 1-19. doi: 10.1007/s10803-022-05465-7
Akingbuwa, Wonuola A., Hammerschlag, Anke R., Bartels, Meike and Middeldorp, Christel M. (2022). Systematic review: molecular studies of common genetic variation in child and adolescent psychiatric disorders. Journal of the American Academy of Child and Adolescent Psychiatry, 61 (2), 227-242. doi: 10.1016/j.jaac.2021.03.020
Doyle, Frances L., Morawska, Alina, Higgins, Daryl J., Havighurst, Sophie S., Mazzucchelli, Trevor G., Toumbourou, John W., Middeldorp, Christel M., Chainey, Carys, Cobham, Vanessa E., Harnett, Paul and Sanders, Matthew R. (2022). Policies are needed to increase the reach and impact of evidence-based parenting supports: a call for a population-based approach to supporting parents, children, and families. Child Psychiatry and Human Development, 54 (3), 1-14. doi: 10.1007/s10578-021-01309-0
Havighurst, Sophie S., Chainey, Carys, Doyle, Frances L., Higgins, Daryl J., Mathews, Ben, Mazzucchelli, Trevor G., Zimmer-Gembeck, Melanie, Andriessen, Karl, Cobham, Vanessa E., Cross, Donna, Dadds, Mark R., Dawe, Sharon, Gray, Kylie M., Guastella, Adam J., Harnett, Paul, Haslam, Divna M., Middeldorp, Christel M., Morawska, Alina, Ohan, Jeneva L., Sanders, Matthew R., Stallman, Helen M., Tonge, Bruce J., Toumbourou, John W., Turner, Karen M.T., Williams, Kate E., Yap, Marie B.H. and Nicholson, Jan M. (2022). A review of Australian Government funding of parenting intervention research. Australian and New Zealand Journal of Public Health, 46 (3), 262-268. doi: 10.1111/1753-6405.13235
Roest, S. L., Siebelink, B. M., Van Ewijk, H., Vermeiren, R. R.J.M., Middeldorp, C. M. and Van Der Lans, R. M. (2021). Sociodemographic and clinical characteristics in child and youth mental health; comparison of routine outcome measurements of an Australian and Dutch outpatient cohort. Epidemiology and Psychiatric Sciences, 30 e74, e74. doi: 10.1017/S2045796021000652
Ensink, Judith B.M., Keding, Taylor J., Henneman, Peter, Venema, Andrea, Papale, Ligia A., Alisch, Reid S., Westerman, Yousha, van Wingen, Guido, Zantvoord, Jasper, Middeldorp, Christel M., Mannens, Marcel M.A.M., Herringa, Ryan J. and Lindauer, Ramon J.L. (2021). Differential DNA methylation is associated with hippocampal abnormalities in pediatric posttraumatic stress disorder. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 6 (11), 1063-1070. doi: 10.1016/j.bpsc.2021.04.016
van der Laan, Camiel M., Morosoli-García, José J., van de Weijer, Steve G. A., Colodro-Conde, Lucía, Ip, Hill F., van der Laan, Camiel M., Krapohl, Eva M. L., Brikell, Isabell, Sánchez-Mora, Cristina, Nolte, Ilja M., Pourcain, Beate St, Bolhuis, Koen, Palviainen, Teemu, Zafarmand, Hadi, Gordon, Scott, Zayats, Tetyana, Aliev, Fazil, Jiang, Chang, Wang, Carol A., Saunders, Gretchen, Karhunen, Ville, Hammerschlag, Anke R., Adkins, Daniel E., Border, Richard, Peterson, Roseann E., Prinz, Joseph A., Thiering, Elisabeth, Seppälä, Ilkka, Vilor-Tejedor, Natàlia ... the ACTION Consortium (2021). Continuity of genetic risk for aggressive behavior across the life-course. Behavior Genetics, 51 (5), 592-606. doi: 10.1007/s10519-021-10076-6
De Young, Alexandra C., Vasileva, Mira, Boruszak-Kiziukiewicz, Joanna, Demipence Seçinti, Dilara, Christie, Hope, Egberts, Marthe R., Anastassiou-Hadjicharalambous, Xenia, Marsac, Meghan L., Ruiz, Gemma, COVID-19 Unmasked Global Collaboration, Middeldorp, Christel and Cobham, Vanessa E. (2021). COVID-19 Unmasked Global Collaboration Protocol: longitudinal cohort study examining mental health of young children and caregivers during the pandemic. European Journal of Psychotraumatology, 12 (1) 1940760, 1-14. doi: 10.1080/20008198.2021.1940760
Ip, Hill F., van der Laan, Camiel M., Krapohl, Eva M. L., Brikell, Isabell, Sánchez-Mora, Cristina, Nolte, Ilja M., St Pourcain, Beate, Bolhuis, Koen, Palviainen, Teemu, Zafarmand, Hadi, Colodro-Conde, Lucía, Gordon, Scott, Zayats, Tetyana, Aliev, Fazil, Jiang, Chang, Wang, Carol A., Saunders, Gretchen, Karhunen, Ville, Hammerschlag, Anke R., Adkins, Daniel E., Border, Richard, Peterson, Roseann E., Prinz, Joseph A., Thiering, Elisabeth, Seppälä, Ilkka, Vilor-Tejedor, Natàlia, Ahluwalia, Tarunveer S., Day, Felix R., Hottenga, Jouke-Jan ... Boomsma, Dorret I. (2021). Genetic association study of childhood aggression across raters, instruments, and age. Translational Psychiatry, 11 (1) 413, 413. doi: 10.1038/s41398-021-01480-x
Najman, Jake M., Bor, William, Williams, Gail M., Middeldorp, Christel M., Mamun, Abdullah A., Clavarino, Alexandra M. and Scott, James G. (2021). Does the millennial generation of women experience more mental illness than their mothers?. BMC Psychiatry, 21 (1) 359, 359. doi: 10.1186/s12888-021-03361-5
Enticott, Peter G, Barlow, Karen, Guastella, Adam J, Licari, Melissa K, Rogasch, Nigel C, Middeldorp, Christel M, Clark, Scott R, Vallence, Ann-Maree, Boulton, Kelsie A, Hickie, Ian B, Whitehouse, Andrew J O, Galletly, Cherrie, Alvares, Gail A, Fujiyama, Hakuei, Heussler, Helen, Craig, Jeffrey M, Kirkovski, Melissa, Mills, Natalie T, Rinehart, Nicole J, Donaldson, Peter H, Ford, Talitha C, Caeyenberghs, Karen, Albein-Urios, Natalia, Bekkali, Soukayna and Fitzgerald, Paul B (2021). Repetitive transcranial magnetic stimulation (rTMS) in autism spectrum disorder: protocol for a multicentre randomised controlled clinical trial. BMJ Open, 11 (7) e046830, 1-9. doi: 10.1136/bmjopen-2020-046830
Novins, Douglas K., Stoddard, Joel, Althoff, Robert R., Charach, Alice, Cortese, Samuele, Cullen, Kathryn Regan, Frazier, Jean A., Glatt, Stephen J., Henderson, Schuyler W., Herringa, Ryan J., Hulvershorn, Leslie, Kieling, Christian, McBride, Anne B., McCauley, Elizabeth, Middeldorp, Christel M., Reiersen, Angela M., Rockhill, Carol M., Sagot, Adam J., Scahill, Lawrence, Simonoff, Emily, Stewart, S. Evelyn, Szigethy, Eva, Taylor, Jerome H., White, Tonya and Zima, Bonnie T. (2021). Editors’ Note and Special Communication: Research Priorities in Child and Adolescent Mental Health Emerging From the COVID-19 Pandemic. Journal of the American Academy of Child and Adolescent Psychiatry, 60 (5), 544-554.e8. doi: 10.1016/j.jaac.2021.03.005
Thorp, Jackson G., Campos, Adrian I., Grotzinger, Andrew D., Gerring, Zachary F., An, Jiyuan, Ong, Jue-Sheng, Wang, Wei, Shringarpure, Suyash, Byrne, Enda M., MacGregor, Stuart, Martin, Nicholas G., Medland, Sarah E., Middeldorp, Christel M. and Derks, Eske M. (2021). Symptom-level modelling unravels the shared genetic architecture of anxiety and depression. Nature Human Behaviour, 5 (10), 1432-1442. doi: 10.1038/s41562-021-01094-9
Jami, Eshim S., Hammerschlag, Anke R., Bartels, Meike and Middeldorp, Christel M. (2021). Parental characteristics and offspring mental health and related outcomes: a systematic review of genetically informative literature. Translational Psychiatry, 11 (1) 197, 197. doi: 10.1038/s41398-021-01300-2
Bisset, Matthew, Winter, Leanne, Middeldorp, Christel M., Coghill, David, Zendarski, Nardia, Bellgrove, Mark A. and Sciberras, Emma (2021). Recent attitudes toward ADHD in the broader community: a systematic review. Journal of Attention Disorders, 26 (4), 1-12. doi: 10.1177/10870547211003671
Rajula, Hema Sekhar Reddy, Manchia, Mirko, Agarwal, Kratika, Akingbuwa, Wonuola A., Allegrini, Andrea G., Diemer, Elizabeth, Doering, Sabrina, Haan, Elis, Jami, Eshim S., Karhunen, Ville, Leone, Marica, Schellhas, Laura, Thompson, Ashley, van den Berg, Stéphanie M., Bergen, Sarah E., Kuja-Halkola, Ralf, Hammerschlag, Anke R., Järvelin, Marjo Riitta, Leval, Amy, Lichtenstein, Paul, Lundstrom, Sebastian, Mauri, Matteo, Munafò, Marcus R., Myers, David, Plomin, Robert, Rimfeld, Kaili, Tiemeier, Henning, Ystrom, Eivind, Fanos, Vassilios ... Middeldorp, Christel M. (2021). Overview of CAPICE—Childhood and Adolescence Psychopathology: unravelling the complex etiology by a large Interdisciplinary Collaboration in Europe—an EU Marie Skłodowska-Curie International Training Network. European Child and Adolescent Psychiatry, 31 (5), 829-839. doi: 10.1007/s00787-020-01713-2
Blokland, Gabriëlla A.M., Grove, Jakob, Chen, Chia-Yen, Cotsapas, Chris, Tobet, Stuart, Handa, Robert, Ripke, Stephan, Neale, Benjamin M., Corvin, Aiden, Walters, James T.R., Farh, Kai-How, Holmans, Peter A., Lee, Phil, Bulik-Sullivan, Brendan, Collier, David A., Huang, Hailiang, Pers, Tune H., Agartz, Ingrid, Agerbo, Esben, Albus, Margot, Alexander, Madeline, Amin, Farooq, Bacanu, Silviu A., Begemann, Martin, Belliveau, Richard A., Bene, Judit, Bergen, Sarah E., Bevilacqua, Elizabeth, Bigdeli, Tim B. ... iPSYCH (2021). Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders. Biological Psychiatry, 91 (1), 102-117. doi: 10.1016/j.biopsych.2021.02.972
Shen, Xueyi, Howard, David M., Adams, Mark J., Hill, W. David, Clarke, Toni-Kim, Adams, Mark J., Clarke, Toni-Kim, McIntosh, Andrew M., Deary, Ian J., Wray, Naomi R., Ripke, Stephan, Mattheisen, Manuel, Trzaskowski, Maciej, Byrne, Enda M., Abdellaoui, Abdel, Agerbo, Esben, Air, Tracy M., Andlauer, Till F. M., Bacanu, Silviu-Alin, Bækvad-Hansen, Marie, Beekman, Aartjan T. F., Bigdeli, Tim B., Binder, Elisabeth B., Bryois, Julien, Buttenschøn, Henriette N., Bybjerg-Grauholm, Jonas, Cai, Na, Castelao, Enrique, Christensen, Jane Hvarregaard ... McIntosh, Andrew M. (2020). A phenome-wide association and Mendelian Randomisation study of polygenic risk for depression in UK Biobank. Nature Communications, 11 (1) 2301. doi: 10.1038/s41467-020-16022-0
Najman, Jackob M., Kisely, Steve, Scott, James G., Strathearn, Lane, Clavarino, Alexandra, Williams, Gail M., Middeldorp, Christel and Bernstein, David (2020). Agency notification and retrospective self-reports of childhood maltreatment in a 30-Year cohort: Estimating population prevalence from different data sources. Child Abuse and Neglect, 109 104744, 104744. doi: 10.1016/j.chiabu.2020.104744
Sciberras, Emma, Streatfeild, Jared, Ceccato, Tristan, Pezzullo, Lynne, Scott, James G., Middeldorp, Christel M., Hutchins, Paul, Paterson, Roger, Bellgrove, Mark A. and Coghill, David (2020). Social and economic costs of attention-deficit/hyperactivity disorder across the lifespan. Journal of Attention Disorders, 26 (1) ARTN 1087054720961828, 108705472096182-87. doi: 10.1177/1087054720961828
Hammerschlag, Anke R., Byrne, Enda M., Bartels, Meike, Wray, Naomi R., Middeldorp, Christel M., eQTLGen Consortium, BIOS Consortium, Ahsan, Habibul, Alves, Isabel, Andiappan, Anand, Arindrarto, Wibowo, Awadalla, Philip, Battle, Alexis, Beutner, Frank, Bonder, Marc Jan, Boomsma, Dorret I., Christiansen, Mark, Claringbould, Annique, Deelen, Patrick, Esko, Tõnu, Favé, Marie-Julie, Franke, Lude, Frayling, Timothy, Gharib, Sina A., Gibson, Gregory, Heijmans, Bastiaan T., Hemani, Gibran, Jansen, Rick, Kähönen, Mika, Kalnapenkis, Anette ... Agbessi, Mawussé (2020). Refining attention-deficit/hyperactivity disorder and autism spectrum disorder genetic loci by integrating summary data from genome-wide association, gene expression and DNA methylation studies. Biological Psychiatry, 88 (6), 470-479. doi: 10.1016/j.biopsych.2020.05.002
Krishnamoorthy, Govind, Hessing, Paula, Middeldorp, Christel and Branjerdporn, Melissa (2020). Effects of the ‘Circle of Security’ group parenting program (COS-P) with foster carers: An observational study. Children and Youth Services Review, 115 105082, 105082. doi: 10.1016/j.childyouth.2020.105082
Najman, Jackob. M., Middeldorp, Christel, Williams, Gail M., Scott, James G., McGee, Tara, Bor, William, Clavarino, Alexandra M and Mamun, Abdullah (2020). Illicit drug use by mothers and their daughters in Australia: a comparison of two generations. Addictive Behaviors, 106 106321, 106321. doi: 10.1016/j.addbeh.2020.106321
Cobham, Vanessa E., Hickling, Anna, Kimball, Hayley, Thomas, Hannah J., Scott, James G. and Middeldorp, Christel M. (2020). Systematic review: anxiety in children and adolescents with chronic medical conditions. Journal of the American Academy of Child and Adolescent Psychiatry, 59 (5), 595-618. doi: 10.1016/j.jaac.2019.10.010
Akingbuwa, Wonuola A., Hammerschlag, Anke R., Jami, Eshim S., Allegrini, Andrea G., Karhunen, Ville, Sallis, Hannah, Ask, Helga, Askeland, Ragna B., Baselmans, Bart, Diemer, Elizabeth, Hagenbeek, Fiona A., Havdahl, Alexandra, Hottenga, Jouke-Jan, Mbarek, Hamdi, Rivadeneira, Fernando, Tesli, Martin, Van Beijsterveldt, Catharina, Breen, Gerome, Lewis, Cathryn M., Thapar, Anita, Boomsma, Dorret I., Kuja-Halkola, Ralf, Reichborn-Kjennerud, Ted, Magnus, Per, Rimfeld, Kaili, Ystrom, Eivind, Jarvelin, Marjo-Riitta, Lichtenstein, Paul, Lundstrom, Sebastian ... Middeldorp, Christel M. (2020). Genetic associations between childhood psychopathology and adult depression and associated traits in 42998 individuals: a meta-analysis. JAMA Psychiatry, 77 (7), 715-728. doi: 10.1001/jamapsychiatry.2020.0527
Amare, Azmeraw T., Schubert, Klaus Oliver, Hou, Liping, Clark, Scott R., Papiol, Sergi, Cearns, Micah, Heilbronner, Urs, Degenhardt, Franziska, Tekola-Ayele, Fasil, Hsu, Yi-Hsiang, Shekhtman, Tatyana, Adli, Mazda, Akula, Nirmala, Akiyama, Kazufumi, Ardau, Raffaella, Arias, Bárbara, Aubry, Jean-Michel, Backlund, Lena, Bhattacharjee, Abesh Kumar, Bellivier, Frank, Benabarre, Antonio, Bengesser, Susanne, Biernacka, Joanna M., Birner, Armin, Brichant-Petitjean, Clara, Cervantes, Pablo, Chen, Hsi-Chung, Chillotti, Caterina, Cichon, Sven ... Baune, Bernhard T. (2020). Association of polygenic score for major depression with response to lithium in patients with bipolar disorder. Molecular Psychiatry, 26 (6), 2457-2470. doi: 10.1038/s41380-020-0689-5
Campbell, Timothy C. H., Reupert, Andrea, Sutton, Keith, Basu, Soumya, Davidson, Gavin, Middeldorp, Christel M., Naughton, Michael and Maybery, Darryl (2020). Prevalence of mental illness among parents of children receiving treatment within child and adolescent mental health services (CAMHS): a scoping review. European Child and Adolescent Psychiatry, 30 (7), 997-1012. doi: 10.1007/s00787-020-01502-x
Coleman, Jonathan R. I., Peyrot, Wouter J., Purves, Kirstin L., Davis, Katrina A. S., Rayner, Christopher, Choi, Shing Wan, Hübel, Christopher, Gaspar, Héléna A., Kan, Carol, Van der Auwera, Sandra, Adams, Mark James, Lyall, Donald M., Choi, Karmel W., Dunn, Erin C., Vassos, Evangelos, Danese, Andrea, Maughan, Barbara, Grabe, Hans J., Lewis, Cathryn M., O’Reilly, Paul F., McIntosh, Andrew M., Smith, Daniel J., Wray, Naomi R., Hotopf, Matthew, Eley, Thalia C., Breen, Gerome, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Trzaskowski, Maciej, Byrne, Enda M. ... Middeldorp, Christel M. (2020). Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank. Molecular Psychiatry, 25 (7), 1430-1446. doi: 10.1038/s41380-019-0546-6
Zendarski, Nardia, Guo, Shuaijun, Sciberras, Emma, Efron, Daryl, Quach, Jon, Winter, Leanne, Bisset, Matthew, Middeldorp, Christel M. and Coghill, David (2020). Examining the Educational Gap for Children with ADHD and Subthreshold ADHD. Journal of Attention Disorders, 26 (2), 1087054720972790-295. doi: 10.1177/1087054720972790
Jami, Eshim S., Eilertsen, Espen Moen, Hammerschlag, Anke R., Qiao, Zhen, Evans, David M., Ystrøm, Eivind, Bartels, Meike and Middeldorp, Christel M. (2020). Maternal and paternal effects on offspring internalizing problems: results from genetic and family-based analyses. American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics, 183 (5), 258-267. doi: 10.1002/ajmg.b.32784
Sciberras, Emma, Patel, Pooja, Stokes, Mark A., Coghill, David, Middeldorp, Christel M., Bellgrove, Mark A., Becker, Stephen P., Efron, Daryl, Stringaris, Argyris, Faraone, Stephen V., Bellows, Susannah T., Quach, Jon, Banaschewski, Tobias, McGillivray, Jane, Hutchinson, Delyse, Silk, Tim J., Melvin, Glenn, Wood, Amanda G., Jackson, Anna, Loram, George, Engel, Lidia, Montgomery, Alicia and Westrupp, Elizabeth (2020). Physical health, media use, and mental health in children and adolescents with ADHD during the COVID-19 pandemic in Australia. Journal of Attention Disorders, 26 (4), 1-14. doi: 10.1177/1087054720978549
Byrne, Enda M., Henders, Anjali K., Hickie, Ian B., Middeldorp, Christel M. and Wray, Naomi R. (2020). Nick Martin and the genetics of depression: sample size, sample size, sample size. Twin Research and Human Genetics, 23 (2), 1-3. doi: 10.1017/thg.2020.13
Lee, Phil H., Anttila, Verneri, Won, Hyejung, Feng, Yen-Chen A., Rosenthal, Jacob, Zhu, Zhaozhong, Tucker-Drob, Elliot M., Nivard, Michel G., Grotzinger, Andrew D., Posthuma, Danielle, Wang, Meg M.-J., Yu, Dongmei, Stahl, Eli A., Walters, Raymond K., Anney, Richard J.L., Duncan, Laramie E., Ge, Tian, Adolfsson, Rolf, Banaschewski, Tobias, Belangero, Sintia, Cook, Edwin H., Coppola, Giovanni, Derks, Eske M., Hoekstra, Pieter J., Kaprio, Jaakko, Keski-Rahkonen, Anna, Kirov, George, Kranzler, Henry R., Luykx, Jurjen J. ... Smoller, Jordan W. (2019). Genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders. Cell, 179 (7), 1469-1482.e11. doi: 10.1016/j.cell.2019.11.020
Czamara, Darina, Eraslan, Gökçen, Page, Christian M., Lahti, Jari, Lahti-Pulkkinen, Marius, Hämäläinen, Esa, Kajantie, Eero, Laivuori, Hannele, Villa, Pia M., Reynolds, Rebecca M., Nystad, Wenche, Håberg, Siri E., London, Stephanie J., O’Donnell, Kieran J., Garg, Elika, Meaney, Michael J., Entringer, Sonja, Wadhwa, Pathik D., Buss, Claudia, Jones, Meaghan J., Lin, David T. S., MacIsaac, Julie L., Kobor, Michael S., Koen, Nastassja, Zar, Heather J., Koenen, Karestan C., Dalvie, Shareefa, Stein, Dan J., Kondofersky, Ivan ... Binder, Elisabeth B. (2019). Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns. Nature Communications, 10 (1) 2548. doi: 10.1038/s41467-019-10461-0
Doering, Sabrina, Lichtenstein, Paul, Gillberg, Christopher, Boomsma, D. I., Van Beijsterveldt, Toos C. E. M., Ligthart, Lannie, Willemsen, Gonneke, De Geus, Eco, Middeldorp, Christel M., Bartels, Meike, Kuja-Halkola, Ralf and Lundström, Sebastian (2019). Anxiety at age 15 predicts psychiatric diagnoses and suicidal ideation in late adolescence and young adulthood: Results from two longitudinal studies. BMC Psychiatry, 19 (1) 363, 363. doi: 10.1186/s12888-019-2349-3
Andlauer, Till F. M., Guzman-Parra, Jose, Streit, Fabian, Strohmaier, Jana, González, Maria José, Gil Flores, Susana, Cabaleiro Fabeiro, Francisco J., del Río Noriega, Francisco, Perez, Fermin Perez, Haro González, Jesus, Orozco Diaz, Guillermo, de Diego-Otero, Yolanda, Moreno-Küstner, Berta, Auburger, Georg, Degenhardt, Franziska, Heilmann-Heimbach, Stefanie, Herms, Stefan, Hoffmann, Per, Frank, Josef, Foo, Jerome C., Treutlein, Jens, Witt, Stephanie H., Cichon, Sven, Kogevinas, Manolis, Stahl, Eli A, Breen, Gerome, Forstner, Andreas J, McQuillin, Andrew, Ripke, Stephan ... Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium (2019). Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders. Molecular Psychiatry, 26 (4), 1286-1298. doi: 10.1038/s41380-019-0558-2
Coleman, Jonathan R.I., Gaspar, Héléna A., Bryois, Julien, Byrne, Enda M., Forstner, Andreas J., Holmans, Peter A., de Leeuw, Christiaan A., Mattheisen, Manuel, McQuillin, Andrew, Whitehead Pavlides, Jennifer M., Pers, Tune H., Ripke, Stephan, Stahl, Eli A., Steinberg, Stacy, Trubetskoy, Vassily, Trzaskowski, Maciej, Wang, Yunpeng, Abbott, Liam, Abdellaoui, Abdel, Adams, Mark J., Adolfsson, Annelie Nordin, Agerbo, Esben, Akil, Huda, Albani, Diego, Alliey-Rodriguez, Ney, Als, Thomas D., Andlauer, Till F.M., Anjorin, Adebayo, Antilla, Verneri ... Breen, Gerome (2019). The genetics of the mood disorder spectrum: Genome-wide association analyses of more than 185,000 cases and 439,000 controls. Biological Psychiatry, 88 (2), 169-184. doi: 10.1016/j.biopsych.2019.10.015
Middeldorp, Christel M. (2019). Editorial: childhood stress and psychopathology: it’s not too early to look at biological aging. Journal of the American Academy of Child and Adolescent Psychiatry, 59 (1), 38-39. doi: 10.1016/j.jaac.2019.09.020
Schwabe, I., Milaneschi, Y., Gerring, Z., Sullivan, P. F., Schulte, E., Suppli, N. P., Thorp, J. G., Derks, E. M. and Middeldorp, C. M. (2019). Unraveling the genetic architecture of major depressive disorder: Merits and pitfalls of the approaches used in genome-wide association studies. Psychological Medicine, 49 (16), 2646-2656. doi: 10.1017/S0033291719002502
Ensink, Judith B. M., de Moor, Marleen H. M., Zafarmand, Mohammad Hadi, de Laat, Sanne, Uitterlinden, André, Vrijkotte, Tanja G. M., Lindauer, Ramón and Middeldorp, Christel M. (2019). Maternal environmental risk factors and the development of internalizing and externalizing problems in childhood: the complex role of genetic factors. American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics, 183 (1) ajmg.b.32755, 17-25. doi: 10.1002/ajmg.b.32755
Glanville, Kylie P., Coleman, Jonathan R. I., Hanscombe, Ken B., Euesden, Jack, Choi, Shing Wan, Purves, Kirstin L., Breen, Gerome, Air, Tracy M., Andlauer, Till F. M., Baune, Bernhard T., Binder, Elisabeth B., Blackwood, Douglas H. R., Boomsma, Dorret I., Buttenschøn, Henriette N., Colodro-Conde, Lucía, Dannlowski, Udo, Direk, Nese, Dunn, Erin C., Forstner, Andreas J., de Geus, Eco J. C., Grabe, Hans J., Hamilton, Steven P., Jones, Ian, Jones, Lisa A., Knowles, James A., Kutalik, Zoltán, Levinson, Douglas F., Lewis, Glyn, Lind, Penelope A. ... Børglum, Anders D. (2019). Classical human leukocyte antigen alleles and C4 haplotypes are not significantly associated With depression. Biological Psychiatry, 87 (5), 419-430. doi: 10.1016/j.biopsych.2019.06.031
Hammerschlag, Anke R., de Leeuw, Christiaan A., Middeldorp, Christel M. and Polderman, Tinca J. C. (2019). Synaptic and brain-expressed gene sets relate to the shared genetic risk across five psychiatric disorders. Psychological Medicine, 50 (10), 1-11. doi: 10.1017/s0033291719001776
Middeldorp, C. M. (2019). Genetic diagnostics: part of the psychiatric clinic Genetisch onderzoek: onderdeel van psychiatrische kliniek. Tijdschrift voor psychiatrie, 61 (6), 373-374.
Choi, Karmel W., Chen, Chia-Yen, Stein, Murray B., Klimentidis, Yann C., Wang, Min-Jung, Koenen, Karestan C., Smoller, Jordan W., Wray, Naomi R., Ripke, Stephan, Mattheisen, Manuel, Trzaskowski, Maciej, Byrne, Enda M., Abdellaoui, Abdel, Adams, Mark J., Agerbo, Esben, Air, TracyM., Andlauer, Till F. M., Bacanu, Silviu-Alin, Baekvad-Hansen, Marie, Beekman, Aartjan T. F., Bigdeli, Tim B., Binder, Elisabeth B., Blackwood, Douglas H. R., Bryois, Julien, Buttenschon, Henriette N., Bybjerg-Grauholm, Jonas, Cai, Na, Castelao, Enrique, Hvarregaard, Jane ... Sullivan, Patrick F. (2019). Assessment of bidirectional relationships between physical activity and depression among adults A 2-Sample mendelian randomization study. JAMA Psychiatry, 76 (4), 399-408. doi: 10.1001/jamapsychiatry.2018.4175
Gaspar, Héléna A., Gerring, Zachary, Hübel, Christopher, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Middeldorp, Christel M., Derks, Eske M. and Breen, Gerome (2019). Using genetic drug-target networks to develop new drug hypotheses for major depressive disorder. Translational Psychiatry, 9 (1) 117, 117. doi: 10.1038/s41398-019-0451-4
Grove, Jakob, Ripke, Stephan, Als, Thomas D., Mattheisen, Manuel, Walters, Raymond K., Won, Hyejung, Pallesen, Jonatan, Agerbo, Esben, Andreassen, Ole A., Anney, Richard, Awashti, Swapnil, Belliveau, Rich, Bettella, Francesco, Buxbaum, Joseph D., Bybjerg-Grauholm, Jonas, Bækvad-Hansen, Marie, Cerrato, Felecia, Chambert, Kimberly, Christensen, Jane H., Churchhouse, Claire, Dellenvall, Karin, Demontis, Ditte, De Rubeis, Silvia, Devlin, Bernie, Djurovic, Srdjan, Dumont, Ashley L., Goldstein, Jacqueline I., Hansen, Christine S., Hauberg, Mads Engel ... Børglum, Anders D. (2019). Identification of common genetic risk variants for autism spectrum disorder. Nature Genetics, 51 (3), 431-444. doi: 10.1038/s41588-019-0344-8
Middeldorp, Christel M., Felix, Janine F., Mahajan, Anubha, EArly Genetics Lifecourse Epidemiology (EAGLE) consortium, Early Growth Genetics (EGG) consortium, McCarthy, Mark I. and Mamun, Abdullah (2019). The Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) consortia: design, results and future prospects. European Journal of Epidemiology, 34 (3) 34, 279-300. doi: 10.1007/s10654-019-00502-9
Arias-Vásquez, A., Groffen, A. J., Spijker, S., Ouwens, K. G., Klein, M., Vojinovic, D., Galesloot, T. E., Bralten, J., Hottenga, J. J., van der Most, P. J., Kattenberg, V. M., Pool, R., Nolte, I. M., Penninx, B. W.J.H., Fedko, I. O., Dolan, C. V., Nivard, M. G., den Braber, A., van Duijn, C. M., Hoekstra, P. J., Buitelaar, J. K., Kiemeney, L. A., Hoogman, M., Middeldorp, C. M., Draisma, H. H.M., Vermeulen, S. H., Sánchez-Mora, C., Ramos-Quiroga, J. A., Ribasés, M. ... Boomsma, D. I. (2019). A potential role for the STXBP5-AS1 gene in adult ADHD symptoms. Behavior Genetics, 49 (3), 270-285. doi: 10.1007/s10519-018-09947-2
Foo, Jerome C., Streit, Fabian, Frank, Josef, Witt, Stephanie H., Treutlein, Jens, Baune, Bernhard T., Moebus, Susanne, Joeckel, Karl-Heinz, Forstner, Andreas J., Noethen, Markus M., Rietschel, Marcella, Sartorius, Alexander, Kranaster, Laura, Wray, Naomi R., Ripke, Stephan, Mattheisen, Manuel, Trzaskowski, Maciej, Byrne, Enda M., Abdellaoui, Abdel, Adams, Mark J., Agerbo, Esben, Air, Tracy M., Andlauer, Till F. M., Bacanu, Silviu-Alin, Baekvad-Hansen, Marie, Beekman, Aartjan T. F., Bigdeli, Tim B., Binder, Elisabeth B., Blackwood, Douglas H. R. ... Sullivan, Patrick F. (2019). Evidence for increased genetic risk load for major depression in patients assigned to electroconvulsive therapy. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 180 (1), 35-45. doi: 10.1002/ajmg.b.32700
Demontis, Ditte, Walters, Raymond K., Martin, Joanna, Mattheisen, Manuel, Als, Thomas D., Agerbo, Esben, Baldursson, Gísli, Belliveau, Rich, Bybjerg-Grauholm, Jonas, Bækvad-Hansen, Marie, Cerrato, Felecia, Chambert, Kimberly, Churchhouse, Claire, Dumont, Ashley, Eriksson, Nicholas, Gandal, Michael, Goldstein, Jacqueline I., Grasby, Katrina L., Grove, Jakob, Gudmundsson, Olafur O., Hansen, Christine S., Hauberg, Mads Engel, Hollegaard, Mads V., Howrigan, Daniel P., Huang, Hailiang, Maller, Julian B., Martin, Alicia R., Martin, Nicholas G., Moran, Jennifer ... Kemp, John P. (2019). Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder. Nature Genetics, 51 (1), 63-75. doi: 10.1038/s41588-018-0269-7
Arnau-Soler, Aleix, Adams, Mark J., Hayward, Caroline, Thomson, Pippa A., Porteous, David, Campbell, Archie, Smith, Blair H., Black, Corri, Padmanabhan, Sandosh, McIntosh, Andrew, Wray, Naomi R., Ripke, Stephan, Mattheisen, Manuel, Trzaskowski, Maciej, Byrne, Enda M., Abdellaoui, Abdel, Agerbo, Esben, Air, Tracy M., Andlauer, Till F.M., Bacanu, Silviu-Alin, Bækvad-Hansen, Marie, Beekman, Aartjan T.F., Bigdeli, Tim B., Binder, Elisabeth B., Blackwood, Douglas H.R., Bryois, Julien, Buttenschøn, Henriette N., Bybjerg-Grauholm, Jonas, Cai, Na ... Sullivan, Patrick F. (2018). Genome-wide interaction study of a proxy for stress-sensitivity and its prediction of major depressive disorder. PLoS ONE, 13 (12) e0209160, e0209160. doi: 10.1371/journal.pone.0209160
de Jong, Simone, Abdalla Diniz, Mateus Jose, Saloma, Andiara, Gadelha, Ary, Santoro, Marcos L., Ota, Vanessa K., Noto, Cristiano, Curtis, Charlesg, Newhouse, Stephen J., Patel, Hamel, Hall, Lynsey S., O'Reilly, Paul F., Belangero, Sintia, Bressan, Rodrigo A., Breen, Gerome, Wray, Naomi R., Ripke, Stephan, Mattheisen, Manuel, Trzaskowski, Maciej, Byrne, Enda M., Abdellaoui, Abdel, Adams, Mark J., Agerbo, Esben, Air, Tracy M., Andlauer, Till F. M., Bacanu, Silviu-Alin, Baekvad-Hansen, Marie, Beekman, Aartjan T. F., Bigdeli, Tim B. ... Major Depressive Disorder and Bipolar Disorder Working Groups of the Psychiatric Genomics Consortium (2018). Applying polygenic risk scoring for psychiatric disorders to a large family with bipolar disorder and major depressive disorder. Communications Biology, 1 (163) 163. doi: 10.1038/s42003-018-0155-y
Wesseldijk, Laura W., Dieleman, Gwen C., van Steensel, Francisa J.A., Bleijenberg, Ellen J., Bartels, Meike, Bögels, Susan M. and Middeldorp, Christel M. (2018). Do parental psychiatric symptoms predict outcome in children with psychiatric disorders? A naturalistic clinical study. Journal of the American Academy of Child and Adolescent Psychiatry, 57 (9), 669-677.e6. doi: 10.1016/j.jaac.2018.05.017
Anttila, Verneri, Bulik-Sullivan, Brendan, Finucane, Hilary K., Walters, Raymond K., Bras, Jose, Duncan, Laramie, Escott-Price, Valentina, Falcone, Guido J., Gormley, Padhraig, Malik, Rainer, Patsopoulos, Nikolaos A., Ripke, Stephan, Wei, Zhi, Yu, Dongmei, Lee, Phil H., Turley, Patrick, Grenier-Boley, Benjamin, Chouraki, Vincent, Kamatani, Yoichiro, Berr, Claudine, Letenneur, Luc, Hannequin, Didier, Amouyel, Philippe, Boland, Anne, Deleuze, Jean-Francois, Duron, Emmanuelle, Vardarajan, Badri N., Reitz, Christiane, Goate, Alison M. ... The Brainstorm Consortium (2018). Analysis of shared heritability in common disorders of the brain. Science, 360 (6395) 8757, 1313-+. doi: 10.1126/science.aap8757
Bartels, Meike, Hendriks, Anne, Mauri, Matteo, Krapohl, Eva, Whipp, Alyce, Bolhuis, Koen, Conde, Lucia Colodro, Luningham, Justin, Fung Ip, Hill, Hagenbeek, Fiona, Roetman, Peter, Gatej, Raluca, Lamers, Audri, Nivard, Michel, van Dongen, Jenny, Lu, Yi, Middeldorp, Christel, van Beijsterveldt, Toos, Vermeiren, Robert, Hankemeijer, Thomas, Kluft, Cees, Medland, Sarah, Lundström, Sebastian, Rose, Richard, Pulkkinen, Lea, Vuoksimaa, Eero, Korhonen, Tellervo, Martin, Nicholas G., Lubke, Gitta ... Boomsma, Dorret I. (2018). Childhood aggression and the co-occurrence of behavioural and emotional problems: results across ages 3-16 years from multiple raters in six cohorts in the EU-ACTION project. European Child & Adolescent Psychiatry, 27 (9), 1-17. doi: 10.1007/s00787-018-1169-1
Wray, Naomi R., Ripke, Stephan, Mattheisen, Manuel, Trzaskowski, Maciej, Byrne, Enda M., Abdellaoui, Abdel, Adams, Mark J., Agerbo, Esben, Air, Tracy M., Andlauer, Till M. F., Bacanu, Silviu-Alin, Baekvad-Hansen, Marie, Beekman, Aartjan F. T., Bigdeli, Tim B., Binder, Elisabeth B., Blackwood, Douglas R. H., Bryois, Julien, Buttenschon, Henriette N., Bybjerg-Grauholm, Jonas, Cai, Na, Castelao, Enrique, Christensen, Jane Hvarregaard, Clarke, Toni-Kim, Coleman, Jonathan I. R., Colodro-Conde, Lucia, Couvy-Duchesne, Baptiste, Craddock, Nick, Crawford, Gregory E., Crowley, Cheynna A. ... Sullivan, Patrick F. (2018). Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression. Nature Genetics, 50 (5), 668-+. doi: 10.1038/s41588-018-0090-3
Wesseldijk, L. W., Dieleman, G. C., van Steensel, F. J. A., Bartels, M., Hudziak, J. J., Lindauer, R. J. L., Bögels, S. M. and Middeldorp, C. M. (2018). Risk factors for parental psychopathology: a study in families with children or adolescents with psychopathology. European Child & Adolescent Psychiatry, 27 (12), 1575-1584. doi: 10.1007/s00787-018-1156-6
Middeldorp, Christel M. and Wray, Naomi R. (2018). The value of polygenic analyses in psychiatry. World Psychiatry, 17 (1), 26-28. doi: 10.1002/wps.20480
Barbu, Miruna C., Zeng, Yanni, Shen, Xueyi, Cox, Simon R., Clarke, Toni-Kim, Gibson, Jude, Adams, Mark J., Johnstone, Mandy, Haley, Chris S., Lawrie, Stephen M., Deary, Ian J., Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Wray, Naomi R., Ripke, Stephan, Mattheisen, Manuel, Trzaskowski, Maciej, Byrne, Enda M., Abdellaoui, Abdel, Adams, Mark J., Agerbo, Esben, Air, Tracy M., Andlauer, Till F.M., Bacanu, Silviu-Alin, Bækvad-Hansen, Marie, Beekman, Aartjan T.F., Bigdeli, Tim B., Binder, Elisabeth B., Blackwood, Douglas H.R., Bryois, Julien ... Whalley, Heather C. (2018). Association of whole-genome and NETRIN1 signaling pathway–derived polygenic risk scores for major depressive disorder and white matter microstructure in the UK Biobank. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 4 (1), 91-100. doi: 10.1016/j.bpsc.2018.07.006
Treur, Jorien L., Vink, Jacqueline M., Boomsma, Dorret I. and Middeldorp, Christel M. (2018). Corrigendum to “Spousal resemblance for smoking: Underlying mechanisms and effects of cohort and age” [Drug Alcohol Depend. 153 (2015) 221–228] (S0376871615002549) (10.1016/j.drugalcdep.2015.05.018)). Drug and Alcohol Dependence, 182, 123-123. doi: 10.1016/j.drugalcdep.2017.11.002
Rietschel, Liz, Streit, Fabian, Zhu, Gu, McAloney, Kerrie, Frank, Josef, Couvy-Duchesne, Baptiste, Witt, Stephanie H., Binz, Tina M., Bolton, Jennifer L., Hayward, Caroline, Direk, Nese, Anderson, Anna, Huffman, Jennifer, Wilson, James F., Campbell, Harry, Rudan, Igor, Wright, Alan, Hastie, Nicholas, Wild, Sarah H., Velders, Fleur P., Hofman, Albert, Uitterlinden, Andre G., Lahti, Jari, Räikkönen, Katri, Kajantie, Eero, Widen, Elisabeth, Palotie, Aarno, Eriksson, Johan G., Kaakinen, Marika ... Rietschel, Marcella (2017). Hair Cortisol in Twins: Heritability and Genetic Overlap with Psychological Variables and Stress-System Genes. Scientific Reports, 7 (1) 15351, 15351. doi: 10.1038/s41598-017-11852-3
Nivard, Michel G., Gage, Suzanne H., Hottenga, Jouke J. , van Beijsterveldt, Catharina E. M., Abdellaoui, Abdel, Bartels, Meike, Baselmans, Bart M. L., Ligthart, Lannie, St Pourcain, Beate, Boomsma, Dorret I., Munafò, Marcus R. and Middeldorp, Christel M. (2017). Genetic overlap between schizophrenia and developmental psychopathology: longitudinal and multivariate polygenic risk prediction of common psychiatric traits during development. Schizophrenia Bulletin, 43 (6), 1197-1207. doi: 10.1093/schbul/sbx031
Milaneschi, Yuri, Lamers, Femke, Peyrot, Wouter J., Baune, Bernhard T., Breen, Gerome, Dehghan, Abbas, Forstner, Andreas J., Grabe, Hans J., Homuth, Georg, Kan, Carol, Lewis, Cathryn, Mullins, Niamh, Nauck, Matthias, Pistis, Giorgio, Preisig, Martin, Rivera, Margarita, Rietschel, Marcella, Streit, Fabian, Strohmaier, Jana, Teumer, Alexander, Van der Auwera, Sandra, Wray, Naomi R., Boomsma, Dorret I., Penninx, Brenda W. J. H., for the CHARGE Inflammation Working Group and the Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium and Middeldorp, Christel (2017). Genetic Association of Major Depression With Atypical Features and Obesity-Related Immunometabolic Dysregulations. JAMA Psychiatry, 74 (12), 1214-1225. doi: 10.1001/jamapsychiatry.2017.3016
Witt, S. H., Streit, F., Jungkunz, M., Frank, J., Awasthi, S., Reinbold, C. S., Treutlein, J., Degenhardt, F., Forstner, A. J., Heilmann-Heimbach, S., Dietl, L., Schwarze, C. E., Schendel, D., Strohmaier, J., Abdellaoui, A., Adolfsson, R., Air, T. M., Akil, H., Alda, M., Alliey-Rodriguez, N., Andreassen, O. A., Babadjanova, G., Bass, N. J., Bauer, M., Baune, B. T., Bellivier, F., Bergen, S., Bethell, A., Biernacka, J. M. ... Rietschel, M. (2017). Genome-wide association study of borderline personality disorder reveals genetic overlap with bipolar disorder, major depression and schizophrenia.. Translational psychiatry, 7 (6), e1155-e1155. doi: 10.1038/tp.2017.115
Wesseldijk, Laura W., Bartels, Meike, Vink, Jacqueline M., van Beijsterveldt, Catharina E. M., Ligthart, Lannie, Boomsma, Dorret I. and Middeldorp, Christel M. (2017). Genetic and environmental influences on conduct and antisocial personality problems in childhood, adolescence, and adulthood. European Child & Adolescent Psychiatry, 27 (9), 1-10. doi: 10.1007/s00787-017-1014-y
Culverhouse, R. C., Saccone, N. L., Horton, A. C., Ma, Y., Anstey, K. J., Banaschewski, T., Burmeister, M., Cohen-Woods, S., Etain, B., Fisher, H. L., Goldman, N., Guillaume, S., Horwood, J., Juhasz, G., Lester, K. J., Mandelli, L., Middeldorp, C. M., Olie, E., Villafuerte, S., Air, T. M., Araya, R., Bowes, L., Burns, R., Byrne, E. M., Coffey, C., Coventry, W. L., Gawronski, K. A. B., Glei, D., Hatzimanolis, A. ... Bierut, L. J. (2017). Collaborative meta-analysis finds no evidence of a strong interaction between stress and 5-HTTLPR genotype contributing to the development of depression. Molecular Psychiatry, 23 (1), 133-142. doi: 10.1038/mp.2017.44
Wesseldijk, Laura W., Fedko, Iryna O., Bartels, Meike, Nivard, Michel G., van Beijsterveldt, Catharina E. M., Boomsma, Dorret I. and Middeldorp, Christel M. (2017). Psychopathology in 7-year-old children: Differences in maternal and paternal ratings and the genetic epidemiology. American Journal of Medical Genetics Part B-Neuropsychiatric Genetics, 174 (3), 251-260. doi: 10.1002/ajmg.b.32500
Bigdeli, T. B., Ripke, S., Peterson, R. E., Trzaskowski, M., Bacanu, S-A, Abdellaoui, A., Andlauer, T. F. M., Beekman, A. T. F., Berger, K., Blackwood, D. H. R., Boomsma, D. I., Breen, G., Buttenschon, H. N., Byrne, E. M., Cichon, S., Clarke, T-K, Couvy-Duchesne, B., Craddock, N., de Geus, E. J. C., Degenhardt, F., Dunn, E. C., Edwards, A. C., Fanous, A. H., Forstner, A. J., Frank, J., Gill, M., Gordon, S. D., Grabe, H. J., Hamilton, S. P. ... Kendler, K. S. (2017). Genetic effects influencing risk for major depressive disorder in China and Europe. Translational Psychiatry, 7 (3) e1074, e1074-e1074. doi: 10.1038/tp.2016.292
Fedko, Iryna O., Wesseldijk, Laura W., Nivard, Michel G., Hottenga, Jouke-Jan, van Beijsterveldt, Catharina E. M., Middeldorp, Christel M., Bartels, Meike and Boomsma, Dorret I. (2017). Heritability of behavioral problems in 7-year olds based on shared and unique aspects of parental views. Behavior Genetics, 47 (2), 152-163. doi: 10.1007/s10519-016-9823-1
Hinney, A., Kesselmeier, M., Jall, S., Volckmar, A-L, Foecker, M., Antel, J., Heid, I. M., Winkler, T. W., Grant, S. F. A., Guo, Y., Bergen, A. W., Kaye, W., Berrettini, W., Hakonarson, H., Herpertz-Dahlmann, B., de Zwaan, M., Herzog, W., Ehrlich, S., Zipfel, S., Egberts, K. M., Adan, R., Brandys, M., van Elburg, A., Perica, V. Boraska, Franklin, C. S., Tschoep, M. H., Zeggini, E., Bulik, C. M., Collier, D. ... Middeldorp, Christel (2017). Evidence for three genetic loci involved in both anorexia nervosa risk and variation of body mass index. Molecular Psychiatry, 22 (2), 192-201. doi: 10.1038/mp.2016.71
Bot, M., Middeldorp, C. M., de Geus, E. J. C., Lau, H. M., Sinke, M., van Nieuwenhuizen, B., Smit, J. H., Boomsma, D. I. and Penninx, B. W. J. H. (2017). Validity of LIDAS (LIfetime Depression Assessment Self-report): a self-report online assessment of lifetime major depressive disorder. Psychological Medicine, 47 (2), 279-289. doi: 10.1017/S0033291716002312
Nivard, Michel G., Middeldorp, Christel M., Lubke, Gitta, Hottenga, Jouke-Jan, Abdellaoui, Abdel, Boomsma, Dorret I. and Dolan, Conor V. (2016). Detection of gene-environment interaction in pedigree data using genome-wide genotypes. European Journal of Human Genetics, 24 (12), 1803-1809. doi: 10.1038/ejhg.2016.88
Lee, Minyoung, Aggen, Steven H., Otowa, Takeshi, Castelao, Enrique, Preisig, Martin, Grabe, Hans J., Hartman, Catharina A., Oldehinkel, Albertine J., Middeldorp, Christel M., Tiemeier, Henning and Hettema, John M. (2016). Assessment and characterization of phenotypic heterogeneity of anxiety disorders across five large cohorts. International Journal of Methods in Psychiatric Research, 25 (4), 255-266. doi: 10.1002/mpr.1519
Lubke, Gitta H., Miller, Patrick J., Verhulst, Brad, Bartels, Meike, van Beijsterveldt, Toos, Willemsen, Gonneke, Boomsma, Dorret I. and Middeldorp, Christel M. (2016). A powerful phenotype for gene-finding studies derived from trajectory analyses of symptoms of anxiety and depression between age seven and 18. American Journal of Medical Genetics Part B-Neuropsychiatric Genetics, 171 (7), 948-957. doi: 10.1002/ajmg.b.32375
Otowa, T., Hek, K., Lee, M., Byrne, E. M., Mirza, S. S., Nivard, M. G., Bigdeli, T., Aggen, S. H., Adkins, D., Wolen, A., Fanous, A., Keller, M. C., Castelao, E., Kutalik, Z., Auwera, S. V. der, Homuth, G., Nauck, M., Teumer, A., Milaneschi, Y., Hottenga, J-J, Direk, N., Hofman, A., Uitterlinden, A., Mulder, C. L., Henders, A. K., Medland, S. E., Gordon, S., Heath, A. C., Madden, P. A. F. ... Hettema, J. M. (2016). Erratum: Meta-analysis of genome-wide association studies of anxiety disorders (vol 21, pg 1391, 2016). Molecular Psychiatry, 21 (10), 1485-1485. doi: 10.1038/mp.2016.11
Otowa, T., Hek, K., Lee, M., Byrne, E. M., Mirza, S. S., Nivard, M. G., Bigdeli, T., Aggen, S. H., Adkins, D., Wolen, A., Fanous, A., Keller, M. C., Castelao, E., Kutalik, Z., Der Auwera, S. V., Homuth, G., Nauck, M., Teumer, A., Milaneschi, Y., Hottenga, J. -J., Direk, N., Hofman, A., Uitterlinden, A., Mulder, C. L., Henders, A. K., Medland, S. E., Gordon, S., Heath, A. C., Madden, P. A. F. ... Hettema, J. M. (2016). Meta-analysis of genome-wide association studies of anxiety disorders. Molecular Psychiatry, 21 (10), 1391-1399. doi: 10.1038/mp.2015.197
Middeldorp, Christel M., Hammerschlag, Anke R., Ouwens, Klaasjan G., Groen-Blokhuis, Maria M., St Pourcain, Beate, Greven, Corina U., Pappa, Irene, Tiesler, Carla M. T., Ang, Wei, Nolte, Ilja M., Vilor-Tejedor, Natalia, Bacelis, Jonas, Ebejer, Jane L., Zhao, Huiying, Davies, Gareth E., Ehli, Erik A., Evans, David M., Fedko, Iryna O., Guxens, Monica, Hottenga, Jouke-Jan, Hudziak, James J., Jugessur, Astanand, Kemp, John P., Krapohl, Eva, Martin, Nicholas G., Murcia, Mario, Myhre, Ronny, Ormel, Johan, Ring, Susan M. ... Boomsma, Dorret I. (2016). A genome-wide association meta-analysis of attention-deficit/hyperactivity disorder symptoms in population-based pediatric cohorts. Journal of the American Academy of Child and Adolescent Psychiatry, 55 (10), 896-905.e6. doi: 10.1016/j.jaac.2016.05.025
Middeldorp, Christel M., Wesseldijk, Laura W., Hudziak, James J., Verhulst, Frank C., Lindauer, Ramon J. L. and Dieleman, Gwen C. (2016). Parents of children with psychopathology: psychiatric problems and the association with their child’s problems. European Child and Adolescent Psychiatry, 25 (8), 919-927. doi: 10.1007/s00787-015-0813-2
Nivard, Michel G., Lubke, Gitta H., Dolan, Conor V., Evans, David M., St. Pourcain, Beate, Munafo, Marcus R. and Middeldorp, Christel M. (2016). Joint developmental trajectories of internalizing and externalizing disorders between childhood and adolescence. Development and Psychopathology, 29 (3), 1-10. doi: 10.1017/S0954579416000572
Hagenbeek, Fiona A., Kluft, Cornelis, Hankemeier, Thomas, Bartels, Meike, Draisma, Harmen H. M., Middeldorp, Christel M., Berger, Ruud, Noto, Antonio, Lussu, Milena, Pool, Rene, Fanos, Vassilios and Boomsma, Dorret I. (2016). Discovery of biochemical biomarkers for aggression: A role for metabolomics in psychiatry. American Journal of Medical Genetics Part B-Neuropsychiatric Genetics, 171 (5), 719-732. doi: 10.1002/ajmg.b.32435
Porsch, Robert M., Middeldorp, Christel M., Cherny, Stacey S., Krapohl, Eva, van Beijsterveldt, Catharina E. M., Loukola, Anu, Korhonen, Tellervo, Pulkkinen, Lea, Corley, Robin, Rhee, Soo, Kaprio, Jaakko, Rose, Richard R., Hewitt, John. K., Sham, Pak, Plomin, Robert, Boomsma, Dorret I. and Bartels, Meike (2016). Longitudinal heritability of childhood aggression. American Journal of Medical Genetics Part B-Neuropsychiatric Genetics, 171 (5), 697-707. doi: 10.1002/ajmg.b.32420
Power, Robert A., Tansey, Katherine E., Buttenschøn, Henriette Nørmølle, Cohen-Woods, Sarah, Bigdeli, Tim, Hall, Lynsey S., Kutalik, Zoltán, Lee, S. Hong, Ripke, Stephan, Steinberg, Stacy, Teumer, Alexander, Viktorin, Alexander, Wray, Naomi R., Arolt, Volker, Baune, Bernard T., Boomsma, Dorret I., Børglum, Anders D., Byrne, Enda M., Castelao, Enrique, Craddock, Nick, Craig, Ian, Dannlowski, Udo, Deary, Ian J., Degenhardt, Franziska, Forstner, Andreas J., Gordon, Scott D., Grabe, Hans J., Grove, Jakob, Hamilton, Steven P. ... Lewis, Cathryn M. (2016). Genome-wide association for major depression through age at onset stratification: Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium. Biological Psychiatry, 81 (4), 325-335. doi: 10.1016/j.biopsych.2016.05.010
Wesseldijk, L. W., Dieleman, G. C., Lindauer, R. J. L., Bartels, M., Willemsen, G., Hudziak, J. J., Boomsma, D. I. and Middeldorp, C. M. (2016). Spousal resemblance in psychopathology: a comparison of parents of children with and without psychopathology. European Psychiatry, 34, 49-55. doi: 10.1016/j.eurpsy.2016.01.2423
Van Veen, S. C., Batelaan, N. M., Wesseldijk, L. W., Rozeboom, J. and Middeldorp, C. M. (2016). Psychopathology in families: An integral approach via the family outpatient clinic Psychiatrische stoornissen binnen gezinnen: Een integrale benadering via de familiepoli. Tijdschrift voor Psychiatrie, 58 (2), 95-104.
Molenaar, Dylan, Middeldorp, Christel M., Willemsen, Gonneke, Ligthart, Lannie, Nivard, Michel G. and Boomsma, Dorret I. (2016). Evidence for Gender-Dependent Genotype by Environment Interaction in Adult Depression. Behavior Genetics, 46 (1), 59-71. doi: 10.1007/s10519-015-9752-4
Felix, Janine F., Bradfield, Jonathan P., Monnereau, Claire, van der Valk, Ralf J. P., Stergiakouli, Evie, Chesi, Alessandra, Gaillard, Romy, Feenstra, Bjarke, Thiering, Elisabeth, Kreiner-Moller, Eskil, Mahajan, Anubha, Pitkanen, Niina, Joro, Raimo, Cavadino, Alana, Huikari, Ville, Franks, Steve, Groen-Blokhuis, Maria M., Cousminer, Diana L., Marsh, Julie A., Lehtimaki, Terho, Curtin, John A., Vioque, Jesus, Ahluwalia, Tarunveer S., Myhre, Ronny, Price, Thomas S., Vilor-Tejedor, Natalia, Yengo, Loic, Grarup, Niels, Ntalla, Ioanna ... Jaddoe, Vincent W. V. (2016). Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index. Human Molecular Genetics, 25 (2), 389-403. doi: 10.1093/hmg/ddv472
Nivard, Michel G., Middeldorp, Christel M., Dolan, Conor V. and Boomsma, Dorret I. (2015). Genetic and Environmental Stability of Neuroticism From Adolescence to Adulthood. Twin Research and Human Genetics, 18 (6), 746-754. doi: 10.1017/thg.2015.80
Paternoster, Lavinia, Standl, Marie, Waage, Johannes, Baurecht, Hansjoerg, Hotze, Melanie, Strachan, David P., Curtin, John A., Bonnelykke, Klaus, Tian, Chao, Takahashi, Atsushi, Esparza-Gordillo, Jorge, Alves, Alexessander Couto, Thyssen, Jacob P., den Dekker, Herman T., Ferreira, Manuel A., Altmaier, Elisabeth, Sleiman, Patrick M. A., Xiao, Feng Li, Gonzalez, Juan R., Marenholz, Ingo, Kalb, Birgit, Pino-Yanes, Maria, Xu, Cheng-Jian, Carstensen, Lisbeth, Groen-Blokhuis, Maria M., Venturini, Cristina, Pennell, Craig E., Barton, Sheila J., Levin, Albert M. ... Weidinger, Stephan (2015). Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis. Nature Genetics, 47 (12), 1449-1456. doi: 10.1038/ng.3424
Middeldorp, Christel M. (2015). Genetics and psychiatric disorders: Heritability and the search for genes Genetica en psychische stoornissen op de kinderleeftijd: Erfelijkheid en de zoektocht naar genen. Tijdschrift voor Psychiatrie, 57 (12), 876-880.
Pappa, Irene, Fedko, Iryna O., Mileva-Seitz, Viara R., Hottenga, Jouke-Jan, Bakermans-Kranenburg, Marian J., Bartels, Meike, van Beijsterveldt, Catharina E. M., Jaddoe, Vincent W. V., Middeldorp, Christel M., Rippe, Ralph C. A., Rivadeneira, Fernando, Tiemeier, Henning, Verhulst, Frank C., van Ijzendoorn, Marinus H. and Boomsma, Dorret I. (2015). Erratum: Single nucleotide polymorphism heritability of behavior problems in childhood: genome-wide complex trait analysis (vol 54, pg 737, 2015). Journal of the American Academy of Child and Adolescent Psychiatry, 54 (11), 965-965. doi: 10.1016/j.jaac.2015.09.002
Molenaar, Dylan, Middeldorp, Christel, van Beijsterveldt, Toos and Boomsma, Dorret I. (2015). Analysis of Behavioral and Emotional Problems in Children Highlights the Role of Genotype × Environment Interaction. Child Development, 86 (6), 1999-2016. doi: 10.1111/cdev.12451
Pappa, Irene, Fedko, Iryna O., Mileva-Seitz, Viara R., Hottenga, Jouke-Jan, Bakermans-Kranenburg, Marian J., Bartels, Meike, van Beijsterveldt, Catharina E. M., Jaddoe, Vincent W. V., Middeldorp, Christel M., Rippe, Ralph C. A., Rivadeneira, Fernando, Tiemeier, Henning, Verhulst, Frank C., van Ijzendoorn, Marinus H. and Boomsma, Dorret I. (2015). Single Nucleotide Polymorphism Heritability of Behavior Problems in Childhood: Genome-Wide Complex Trait Analysis. Journal of the American Academy of Child and Adolescent Psychiatry, 54 (9), 737-744. doi: 10.1016/j.jaac.2015.06.004
Fedko, Iryna O., Hottenga, Jouke-Jan, Medina-Gomez, Carolina, Pappa, Irene, van Beijsterveldt, Catharina E. M., Ehli, Erik A., Davies, Gareth E., Rivadeneira, Fernando, Tiemeier, Henning, Swertz, Morris A., Middeldorp, Christel M., Bartels, Meike and Boomsma, Dorret I. (2015). Estimation of Genetic Relationships Between Individuals Across Cohorts and Platforms: Application to Childhood Height. Behavior Genetics, 45 (5), 514-528. doi: 10.1007/s10519-015-9725-7
Treur, Jorien L., Vink, Jacqueline M., Boomsma, Dorret I. and Middeldorp, Christel M. (2015). Spousal resemblance for smoking: Underlying mechanisms and effects of cohort and age. Drug and Alcohol Dependence, 153, 221-228. doi: 10.1016/j.drugalcdep.2015.05.018
Peyrot, W. J., Lee, S. H., Milaneschi, Y., Abdellaoui, A., Byrne, E. M., Esko, T., de Geus, E. J. C., Hemani, G., Hottenga, J. J., Kloiber, S., Levinson, D. F., Lucae, S., Martin, N. G., Medland, S. E., Metspalu, A., Milani, L., Noethen, M. M., Potash, J. B., Rietschel, M., Rietveld, C. A., Ripke, S., Shi, J., Willemsen, G., Zhu, Z., Boomsma, D. I., Wray, N. R., Penninx, B. W. J. H., Major Depressive Disorder Working Group of the Psychiatric GWAS Consortium and Middeldorp, Christel (2015). The association between lower educational attainment and depression owing to shared genetic effects? results in ∼25 000 subjects. Molecular Psychiatry, 20 (6), 735-743. doi: 10.1038/mp.2015.50
Pappa, Irene, St Pourcain, Beate, Benke, Kelly, Cavadino, Alana, Hakulinen, Christian, Nivard, Michel G., Nolte, Ilja M., Tiesler, Carla M. T., Bakermans-Kranenburg, Marian J., Davies, Gareth E., Evans, David M., Geoffroy, Marie-Claude, Grallert, Harald, Groen-Blokhuis, Maria M., Hudziak, James J., Kemp, John P., Keltikangas-Järvinen, Liisa, McMahon, George, Mileva-Seitz, Viara R., Motazedi, Ehsan, Power, Christine, Raitakari, Olli T., Ring, Susan M., Rivadeneira, Fernando, Rodriguez, Alina, Scheet, Paul A., Seppälä, Ilkka, Snieder, Harold, Standl, Marie ... Tiemeier, Henning (2015). A genome-wide approach to children's aggressive behavior: the EAGLE consortium. American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics, 171 (5), 1-11. doi: 10.1002/ajmg.b.32333
Arloth, Janine, Bogdan, Ryan, Weber, Peter, Frishman, Goar, Menke, Andreas, Wagner, Klaus V., Balsevich, Georgia, Schmidt, Mathias V., Karbalai, Nazanin, Czamara, Darina, Altmann, Andre, Truembach, Dietrich, Wurst, Wolfgang, Mehta, Divya, Uhr, Manfred, Klengel, Torsten, Erhardt, Angelika, Carey, Caitlin E., Conley, Emily Drabant, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium (PGC),, Middeldorp, Christel, Ruepp, Andreas, Mueller-Myhsok, Bertram, Hariri, Ahmad R. and Binder, Elisabeth B. (2015). Genetic differences in the immediate transcriptome response to stress predict risk-related brain function and psychiatric disorders. Neuron, 86 (5), 1189-1202. doi: 10.1016/j.neuron.2015.05.034
Byrne, Enda M, Raheja, Uttam K, Stephens, Sarah H, Heath, Andrew C, Madden, Pamela A, Vaswani, Dipika, Nijjar, Gagan V, Ryan, Kathleen A, Youssufi, Hassaan, Gehrman, Philip R, Shuldiner, Alan R, Martin, Nicholas G, Montgomery, Grant W, Wray, Naomi R, Nelson, Elliot C, Mitchell, Braxton D, Postolache, Teodor T, Psychiatric Genetics Consortium Major Depressive Disorder Working Group and Middeldorp, Christel (2015). Seasonality shows evidence for polygenic architecture and genetic correlation with schizophrenia and bipolar disorder. Journal of Clinical Psychiatry, 76 (2), 128-134. doi: 10.4088/JCP.14m08981
O'Dushlaine, Colm, Rossin, Lizzy, Lee, Phil H., Duncan, Laramie, Parikshak, Neelroop N., Newhouse, Stephen, Ripke, Stephan, Neale, Benjamin M., Purcell, Shaun M., Posthuma, Danielle, Nurnberger, John I., Lee, S. Hong, Faraone, Stephen V., Perlis, Roy H., Mowry, Bryan J, Thapar, Anita, Goddard, Michael E., Witte, John S., Absher, Devin, Agartz, Ingrid, Akil, Huda, Amin, Farooq, Andreassen, Ole A., Anjorin, Adebayo, Anney, Richard, Anttila, Verneri, Arking, Dan E., Asherson, Philip, Azevedo, Maria H. ... Breen, Gerome (2015). Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways. Nature Neuroscience, 18 (2), 199-209. doi: 10.1038/nn.3922
Nivard, M. G., Dolan, C. V., Kendler, K. S., Kan, K. J., Willemsen, G., Van Beijsterveldt, C. E.M., Lindauer, R. J.L., Van Beek, J. H.D.A., Geels, L. M., Bartels, M., Middeldorp, C. M. and Boomsma, D. I. (2015). Stability in symptoms of anxiety and depression as a function of genotype and environment: a longitudinal twin study from ages 3 to 63 years. Psychological Medicine, 45 (5), 1039-1049. doi: 10.1017/S003329171400213X
Lindauer, Ramon J. L., Brilleslijper-Kater, Sonja N., Diehle, Julia, Verlinden, Eva, Teeuw, Arianne H., Middeldorp, Christel M., Tuinebreijer, Wilco, Bosschaart, Thekla F., van Duin, Esther and Verhoeff, Arnoud (2014). The Amsterdam Sexual Abuse Case (ASAC)-study in day care centers: longitudinal effects of sexual abuse on infants and very young children and their parents, and the consequences of the persistence of abusive images on the internet. Bmc Psychiatry, 14 (1) 295. doi: 10.1186/s12888-014-0295-7
Perry, John R. B., Day, Felix, Elks, Cathy E., Sulem, Patrick, Thompson, Deborah J., Ferreira, Teresa, He, Chunyan, Chasman, Daniel I., Esko, Toenu, Thorleifsson, Gudmar, Albrecht, Eva, Ang, Wei Q., Corre, Tanguy, Cousminer, Diana L., Feenstra, Bjarke, Franceschini, Nora, Ganna, Andrea, Johnson, Andrew D., Kjellqvist, Sanela, Lunetta, Kathryn L., McMahon, George, Nolte, Ilja M., Paternoster, Lavinia, Porcu, Eleonora, Smith, Albert V., Stolk, Lisette, Teumer, Alexander, Tsernikova, Natalia, Tikkanen, Emmi ... Middeldorp, Christel (2014). Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche. Nature, 514 (7520), 92-97. doi: 10.1038/nature13545
Groen-Blokhuis, Maria M., Middeldorp, Christel M., Kan, Kees-Jan, Abdellaoui, Abdel, van Beijsterveldt, Catharina E. M., Ehli, Erik A., Davies, Gareth E., Scheet, Paul A., Xiao, Xiangjun, Hudziak, James J., Hottenga, Jouke-Jan, Neale, Ben M. and Boomsma, Dorret I. (2014). Attention-deficit/hyperactivity disorder polygenic risk scores predict attention problems in a population-based sample of children. Journal of the American Academy of Child and Adolescent Psychiatry, 53 (10), 1123-1129. doi: 10.1016/j.jaac.2014.06.014
Cousminer, Diana L., Stergiakouli, Evangelia, Berry, Diane J., Ang, Wei, Groen-Blokhuis, Maria M., Koerner, Antje, Siitonen, Niina, Ntalla, Ioanna, Marinelli, Marcella, Perry, John R. B., Kettunen, Johannes, Jansen, Rick, Surakka, Ida, Timpson, Nicholas J., Ring, Susan, Mcmahon, George, Power, Chris, Wang, Carol, Kahonen, Mika, Viikari, Jorma, Lehtimaki, Terho, Middeldorp, Christel M., Pol, Hilleke E. Hulshoff, Neef, Madlen, Weise, Sebastian, Pahkala, Katja, Niinikoski, Harri, Zeggini, Eleftheria, Panoutsopoulou, Kalliope ... Warrington, Nicole M. (2014). Genome-wide association study of sexual maturation in males and females highlights a role for body mass and menarche loci in male puberty. Human Molecular Genetics, 23 (16) ddu150, 4452-4464. doi: 10.1093/hmg/ddu150
Ligthart, Lannie, Hottenga, Jouke-Jan, Lewis, Cathryn M., Farmer, Anne E., Craig, Ian W., Breen, Gerome, Willemsen, Gonneke, Vink, Jacqueline M., Middeldorp, Christel M., Byrne, Enda M., Heath, Andrew C., Madden, Pamela A. F., Pergadia, Michele L., Montgomery, Grant W., Martin, Nicholas G., Penninx, Brenda W. J. H., McGuffin, Peter, Boomsma, Dorret I. and Nyholt, Dale R. (2014). Genetic risk score analysis indicates migraine with and without comorbid depression are genetically different disorders. Human Genetics, 133 (2), 173-186. doi: 10.1007/s00439-013-1370-8
Nivard, M. G., Mbarek, H., Hottenga, J. J., Smit, J. H., Jansen, R., Penninx, B. W., Middeldorp, C. M. and Boomsma, D. I. (2014). Further confirmation of the association between anxiety and CTNND2: replication in humans. Genes, Brain and Behavior, 13 (2), 195-201. doi: 10.1111/gbb.12095
Wray, Naomi R., Lee, Sang Hong, Mehta, Divya, Vinkhuyzen, Anna A. E., Dudbridge, Frank and Middeldorp, Christel M. (2014). Research Review: Polygenic methods and their application to psychiatric traits. Journal of Child Psychology and Psychiatry, 55 (10), 1068-1087. doi: 10.1111/jcpp.12295
Middeldorp, Christel M., Lamb, Diane J., Vink, Jacqueline M., Bartels, Meike, van Beijsterveldt, Catharina E. M. and Boomsma, Dorret I. (2014). Child care, socio-economic status and problem behavior: a study of gene-environment interaction in young Dutch twins. Behavior Genetics, 44 (4), 314-325. doi: 10.1007/s10519-014-9660-z
Benke, Kelly S., Nivard, Michel G., Velders, Fleur P., Walters, Raymond K., Pappa, Irene, Scheet, Paul A., Xiao, Xiangjun, Ehli, Erik A., Palmer, Lyle J., Whitehouse, Andrew J. O., Verhulst, Frank C., Jaddoe, Vincent W., Rivadeneira, Fernando, Groen-Blokhuis, Maria M., van Beijsterveldt, Catharina E. M., Davies, Gareth E., Hudziak, James J., Lubke, Gitta H., Boomsma, Dorret I., Pennell, Craig E., Tiemeier, Henning and Middeldorp, Christel M. (2014). A genome-wide association meta-analysis of preschool internalizing problems. Journal of the American Academy of Child and Adolescent Psychiatry, 53 (6), 667-676. doi: 10.1016/j.jaac.2013.12.028
Wright, Fred A., Sullivan, Patrick F., Brooks, Andrew I., Zou, Fei, Sun, Wei, Xia, Kai, Madar, Vered, Jansen, Rick, Chung, Wonil, Zhou, Yi-Hui, Abdellaoui, Abdel, Batista, Sandra, Butler, Casey, Chen, Guanhua, Chen, Ting-Huei, D'Ambrosiol, David, Gallins, Paul, Ha, Min Jin, Hottenga, Jouke Jan, Huang, Shunping, Kattenberg, Mathijs, Kochar, Jaspreet, Middeldorp, Christel M., Qui, Ani, Shabalinn, Andrey, Tischfield, Jay, Todd, Laura, Tzeng, Jung-Ying, van Grootheest, Gerard ... Boomsma, Dorret I. (2014). Heritability and genomics of gene expression in peripheral blood. Nature Genetics, 46 (5), 430-437. doi: 10.1038/ng.2951
Culverhouse, Robert C., Bowes, Lucy, Breslau, Naomi, Nurnberger, John I. Jr, Burmeister, Margit, Fergusson, David M., Munafo, Marcus, Saccone, Nancy L., Bierut, Laura J., 5-HTTLPR, Stress, and Depression Consortium, Wray, Naomi and Middeldorp, Christel (2013). Protocol for a collaborative meta-analysis of 5-HTTLPR, stress, and depression. BMC Psychiatry, 13 (1) 304, 1-12. doi: 10.1186/1471-244X-13-304
Lee, S. Hong, Ripke, Stephan, Neale, Benjamin M., Faraone, Stephen V., Purcell, Shaun M., Perlis, Roy H., Mowry, Bryan J., Thapar, Anita, Goddard, Michael E., Witte, John S., Absher, Devin, Agartz, Ingrid, Akil, Huda, Amin, Farooq, Andreassen, Ole A., Anjorin, Adebayo, Anney, Richard, Anttila, Verneri, Arking, Dan E., Asherson, Philip, Azevedo, Maria H., Backlund, Lena, Badner, Judith A., Bailey, Anthony J., Banaschewski, Tobias, Barchas, Jack D., Barnes, Michael R., Barrett, Thomas B., Bass, Nicholas ... Wray, Naomi R. (2013). Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nature Genetics, 45 (9), 984-995. doi: 10.1038/ng.2711
Brandys, Marek K., Kas, Martien J. H., van Elburg, Annemarie A., Ophoff, Roel, Slof-Op't Landt, Margarita C. T., Middeldorp, Christel M., Boomsma, Dorret I., van Furth, Eric F., Slagboom, P. Eline and Adan, Roger A. H. (2013). The Val66Met polymorphism of the BDNF gene in anorexia nervosa: new data and a meta-analysis. World Journal of Biological Psychiatry, 14 (6), 441-451. doi: 10.3109/15622975.2011.605470
de Geus, Eco J. C. and Middeldorp, Christel M. (2013). Serotonin transporter gene: will epigenetics prove less depressing than genetics?. Psychosomatic Medicine, 75 (6), 520-522. doi: 10.1097/PSY.0b013e318298708f
Cousminer D.L., Berry D.J., Timpson N.J., Ang W., Thiering E., Byrne E.M., Rob Taal H., Huikari V., Bradfield J.P., Kerkhof M., Groen-Blokhuis M.M., Kreiner-Moller E., Marinelli M., Holst C., Leinonen J.T., Perry J.R.B., Surakka I., Pietilainen O., Kettunen J., Anttila V., Kaakinen M., Sovio U., Pouta A., Das S., Lagou V., Power C., Prokopenko I., Evans D.M., Kemp J.P. ... Middeldorp, Christel (2013). Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity. Human Molecular Genetics, 22 (13), 2735-2747. doi: 10.1093/hmg/ddt104
Groen-Blokhuis, Maria M., Franic, S., van Beijsterveldt, Catharina E. M., de Geus, Eco, Bartels, Meike, Davies, Gareth E., Ehli, Erik A., Xiao, Xiangjun, Scheet, Paul A., Althoff, Robert, Hudziak, James J., Middeldorp, Christel M. and Boomsma, Dorret I. (2013). A prospective study of the effects of breastfeeding and FADS2 polymorphisms on cognition and hyperactivity/attention problems. American Journal of Medical Genetics Part B-Neuropsychiatric Genetics, 162 (5), 457-465. doi: 10.1002/ajmg.b.32175
Groen-Blokhuis, Maria M., Middeldorp, Christel M., Van Beijsterveldt, Catharina E. M. and Boomsma, Dorret I. (2013). Erratum: Crying without a cause and being easily upset in two-year-olds: Heritability and predictive power of behavioral problems (Twin Research and Human Genetics (2011) 14 (393-400) doi:10.1375/twin.14.5.393). Twin Research and Human Genetics, 16 (2), 650-650. doi: 10.1017/thg.2012.52
Major Depressive Disorder Working Group of the Psychiatric GWAS Consortium, Wray, Naomi, Byrne, Enda M., Martin, Nicholas G., Gordon, Scott D., Henders, Anjali K., Montgomery, Grant M., Nyholt, Dale R. and Middeldorp, Christel M. (2013). A mega-analysis of genome-wide association studies for major depressive disorder. Molecular Psychiatry, 18 (4), 497-511. doi: 10.1038/mp.2012.21
Smoller, Jordan W., Craddock, Nicholas, Kendler, Kenneth, Lee, Phil Hyoun, Neale, Benjamin M., Nurnberger, John I., Ripke, Stephan, Santangelo, Susan, Sullivan, Patrick F., Cross-Disorder Group of the Psychiatric Genomics Consortium and Middeldorp, Christel (2013). Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis. The Lancet, 381 (9875), 1371-1379. doi: 10.1016/S0140-6736(12)62129-1
Peyrot, Wouter J., Middeldorp, Christel M., Jansen, Rick, Smit, Johannes H., de Geus, Eco J. C., Hottenga, Jouke-Jan, Willemsen, Gonneke, Vink, Jacqueline M., Virding, Susanne, Barragan, Isabel, Ingelman-Sundberg, Magnus, Sim, Sarah C., Boomsma, Dorret I. and Penninx, Brenda W. J. H. (2013). Strong effects of environmental factors on prevalence and course of major depressive disorder are not moderated by 5-HTTLPR polymorphisms in a large Dutch sample. Journal of Affective Disorders, 146 (1), 91-99. doi: 10.1016/j.jad.2012.08.044
van Beijsterveldt, Catharina E. M., Groen-Blokhuis, Maria, Hottenga, Jouke Jan, Franic, Sanja, Hudziak, James J., Lamb, Diane, Huppertz, Charlotte, de Zeeuw, Eveline, Nivard, Michel, Schutte, Nienke, Swagerman, Suzanne, Glasner, Tina, van Fulpen, Michelle, Brouwer, Cyrina, Stroet, Therese, Nowotny, Dustin, Ehli, Erik A., Davies, Gareth E., Scheet, Paul, Orlebeke, Jacob F., Kan, Kees-Jan, Smit, Dirk, Dolan, Conor V., Middeldorp, Christel M., de Geus, Eco J. C., Bartels, Meike and Boomsma, Dorret I. (2013). The young Netherlands twin register (YNTR): Longitudinal twin and family studies in over 70,000 children. Twin Research and Human Genetics, 16 (1), 252-267. doi: 10.1017/thg.2012.118
Kan, Kees-Jan, Dolan, Conor V., Nivard, Michel G., Middeldorp, Christel M., van Beijsterveldt, Catharina E. M., Willemsen, Gonneke and Boomsma, Dorret I. (2013). Genetic and environmental stability in attention problems across the lifespan: evidence from The Netherlands twin register. Journal of the American Academy of Child and Adolescent Psychiatry, 52 (1), 12-25. doi: 10.1016/j.jaac.2012.10.009
Slof-Op't Landt, Margarita C. T., Bartels, Meike, Middeldorp, Christel M., van Beijsterveldt, Catherina E. M., Slagboom, P. Eline, Boomsma, Dorret I., van Furth, Eric F. and Meulenbelt, Ingrid (2013). Genetic variation at the TPH2 gene influences impulsivity in addition to eating disorders. Behavior Genetics, 43 (1), 24-33. doi: 10.1007/s10519-012-9569-3
Geels, Lot M., Groen-Blokhuis, Maria M., van Beijsterveldt, Catharina E. M., Vink, Jacqueline M., Middeldorp, Christel M., Bartels, Meike, Nelson, Kelly A., Huizenga, Patricia E., Davies, Gareth E. and Boomsma, Dorret I. (2012). Maternal Prenatal Smoking and Offspring Emotional Problems: No Moderating Effect of Maternal or Child 5-HTTLPR Genotype. American Journal of Medical Genetics Part B-Neuropsychiatric Genetics, 159B (8), 1009-1012. doi: 10.1002/ajmg.b.32110
Vink, Jacqueline M., Bartels, Meike, van Beijsterveldt, Toos C. E. M., van Dongen, Jenny, van Beek, Jenny H. D. A., Distel, Marijn A., de Moor, Marleen H. M., Smit, Dirk J. A., Minica, Camelia C., Ligthart, Lannie, Geels, Lot M., Abdellaoui, Abdel, Middeldorp, Christel M., Hottenga, Jouke Jan, Willemsen, Gonneke, de Geus, Eco J. C. and Boomsma, Dorret I. (2012). Sex differences in genetic architecture of complex phenotypes?. PLoS One, 7 (12) e47371, e47371.1-e47371.8. doi: 10.1371/journal.pone.0047371
Lubke, Gitta H., Hottenga, Jouke Jan, Walters, Raymond, Laurin, Charles, de Geus, Eco J. C., Willemsen, Gonneke, Smit, Jan H., Middeldorp, Christel M., Penninx, Brenda W. J. H., Vink, Jacqueline M. and Boomsma, Dorret I. (2012). Estimating the genetic variance of major depressive disorder due to all single nucleotide polymorphisms. Biological Psychiatry, 72 (8), 707-709. doi: 10.1016/j.biopsych.2012.03.011
Luciano, Michelle, Huffman, Jennifer E., Arias-Vasquez, Alejandro, Vinkhuyzen, Anna A. E., Middeldorp, Christel M., Giegling, Ina, Payton, Antony, Davies, Gail, Zgaga, Lina, Janzing, Joost, Ke, Xiayi, Galesloot, Tessel, Hartmann, Annette M., Ollier, William, Tenesa, Albert, Hayward, Caroline, Verhagen, Maaike, Montgomery, Grant W., Hottenga, Jouke-Jan, Konte, Bettina, Starr, John M., Vitart, Veronique, Vos, Pieter E., Madden, Pamela A. F., Willemsen, Gonneke, Konnerth, Heike, Horan, Michael A., Porteous, David J., Campbell, Harry ... Deary, Ian J. (2012). Genome-wide association uncovers shared genetic effects among personality traits and mood states. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 159B (6), 684-695. doi: 10.1002/ajmg.b.32072
Lamb, Diane J., Middeldorp, Christel M., Van Beijsterveldt, Catarina E. M. and Boomsma, Dorret I. (2012). Gene-environment interaction in teacher-rated internalizing and externalizing problem behavior in 7- to 12-year-old twins. Journal of Child Psychology and Psychiatry, 53 (8), 818-825. doi: 10.1111/j.1469-7610.2011.02497.x
Brandys, Marek K., Landt, Margarita C. T. Slof-Op't, van Elburg, Annemarie A., Ophoff, Roel, Verduijn, Willem, Meulenbelt, Ingrid, Middeldorp, Christel M., Boomsma, Dorret I., van Furth, Eric F., Slagboom, Eline, Kas, Martien J. H. and Adan, Roger A. H. (2012). Anorexia nervosa and the Val158Met polymorphism of the COMT gene: Meta-analysis and new data. Psychiatric Genetics, 22 (3), 130-136. doi: 10.1097/YPG.0b013e328351859e
Taal, H. Rob, St Pourcain, Beate, Thiering, Elisabeth, Das, Shikta, Mook-Kanamori, Dennis O., Warrington, Nicole M., Kaakinen, Marika, Kreiner-Møller, Eskil, Bradfield, Jonathan P., Freathy, Rachel M., Geller, Frank, Guxens, Mònica, Cousminer, Diana L., Kerkhof, Marjan, Timpson, Nicholas J., Ikram, M. Arfan, Beilin, Lawrence J., Bønnelykke, Klaus, Buxton, Jessica L., Charoen, Pimphen, Chawes, Bo Lund Krogsgaard, Eriksson, Johan, Evans, David M., Hofman, Albert, Kemp, John P., Kim, Cecilia E., Klopp, Norman, Lahti, Jari, Lye, Stephen J. ... Middeldorp, Christel (2012). Common variants at 12q15 and 12q24 are associated with infant head circumference. Nature Genetics, 44 (5), 532-538. doi: 10.1038/ng.2238
Webb, Bradley T., Guo, An-Yuan, Maher, Brion S., Zhao, Zhongming, van den Oord, Edwin J., Kendler, Kenneth S., Riley, Brien P., Gillespie, Nathan A., Prescott, Carol A., Middeldorp, Christel M., Willemsen, Gonneke, de Geus, Eco J. C., Hottenga, Jouke-Jan, Boomsma, Dorret I., Slagboom, Eline P., Wray, Naomi R., Montgomery, Grant W., Martin, Nicholas G., Wright, Margie J., Heath, Andrew C., Madden, Pamela A., Gelernter, Joel, Knowles, James A., Hamilton, Steven P., Weissman, Myrna M., Fyer, Abby J., Huezo-Diaz, Patricia, McGuffin, Peter, Farmer, Anne ... Hettema, John M. (2012). Meta-analyses of genome-wide linkage scans of anxiety-related phenotypes. European Journal of Human Genetics, 20 (10), 1078-1084. doi: 10.1038/ejhg.2012.47
Lamb, Diane J., Vink, Jacqueline M., Middeldorp, Christel M., van Beijsterveldt, Catharina E. M., Haak, Monique C., Overbeek, Lucy I. H. and Boomsma, Dorret I. (2012). Effects of chorionicity and zygosity on triplet birth weight. Twin Research and Human Genetics, 15 (2), 149-157. doi: 10.1375/twin.15.2.149
Ikram, M. Arfan, Fornage, Myriam, Smith, Albert V., Seshadri, Sudha, Schmidt, Reinhold, Debette, Stephanie, Vrooman, Henri A., Sigurdsson, S., Ropele, Sigurdur, Taal, H. Rob, Mook-Kanamori, Dennis O., Coker, Laura H., Longstreth, W. T., Niessen, Wiro J., Destefano, Anita L., Beiser, Alexa, Zijdenbos, Alex P., Struchalin, Maksim, Jack,Clifford R., Rivadeneira, Fernando, Uitterlinden, Andre G., Knopman, David S., Hartikainen, Anna-Liisa, Pennell, Craig E., Thiering, Elisabeth, Steegers, Eric A. P., Hakonarson, Hakon, Heinrich, Joachim, Palmer, Lyle J. ... . (2012). Common variants at 6q22 and 17q21 are associated with intracranial volume. Nature Genetics, 44 (5), 539-544. doi: 10.1038/ng.2245
Wray, N. R., Pergadia, M. L., Blackwood, D. H. R., Penninx, B. W. J. H., Gordon, S. D., Nyholt, D. R., Ripke, S., MacIntyre, D. J., McGhee, K. A., MacLean, A. W., Smit, J. H., Hottenga, J. J., Willemsen, G., Middeldorp, C. M., De Geus, E. J. C., Lewis, C. M., McGuffin, P., Hickie, I. B., Van Den Oord, E. J. C. G., Liu, J. Z., MacGregor, S., McEvoy, B. P., Byrne, E. M., Medland, S. E., Statham, D. J., Henders, A. K., Heath, A. C., Montgomery, G. W., Martin, N. G. ... Sullivan, P. F. (2012). Genome-wide association study of major depressive disorder: New results, meta-analysis, and lessons learned. Molecular Psychiatry, 17 (1), 36-48. doi: 10.1038/mp.2010.109
Groen-Blokhuis, Maria M., Middeldorp, Christel M., van Beijsterveldt, Catharina E. M. and Boomsma, Dorret I. (2011). Evidence for a causal association of low birth weight and attention problems. Journal of the American Academy of Child and Adolescent Psychiatry, 50 (12), 1247-1254. doi: 10.1016/j.jaac.2011.09.007
Distel, Marijn A., Carlier, Angela, Middeldorp, Christel M., Derom, Catherine A., Lubke, Gitta H. and Boomsma, Dorret I. (2011). Borderline personality traits and adult attention-deficit hyperactivity disorder symptoms: a genetic analysis of comorbidity. American Journal of Medical Genetics Part B - Neuropsychiatric Genetics, 156 (7), 817-825. doi: 10.1002/ajmg.b.31226
Groen-Blokhuis, Maria M., Middeldorp, Christel M., van Beijsterveldt, Catharina E. M. and Boomsma, Dorret I. (2011). Crying without a cause and being easily upset in two-year-olds: Heritability and predictive power of behavioral problems. Twin Research and Human Genetics, 14 (5), 393-400. doi: 10.1375/twin.14.5.393
Distel, M. A., Middeldorp, C. M., Trull, T. J., Derom, C. A., Willemsen, G. and Boomsma, D. I. (2011). Life events and borderline personality features: the influence of gene-environment interaction and gene-environment correlation. Psychological Medicine, 41 (4), 849-860. doi: 10.1017/S0033291710001297
Lamb, Diane J., Middeldorp, Christel M., van Beijsterveldt, Catharina E. M., Vink, Jacqueline M., Haak, Monique C. and Boomsma, Dorret I. (2011). Birth weight in a large series of triplets. BMC Pediatrics, 11 (1) 24, 24.1-24.11. doi: 10.1186/1471-2431-11-24
Slof-Op't Landt, M. C. T. , Meulenbelt, I., Bartels, M., Suchiman, E., Middeldorp, C. M., Houwing-Duistermaat, J. J., van Trier, J., Onkenhout, E. J., Vink, J. M., van Beijsterveldt, C. E. M., Brandys, M. K., Sanders, N., Zipfel, S., Herzog, W., Herpertz-Dahlmann, B., Klampfl, K., Fleischhaker, C., Zeeck, A., de Zwaan, M., Herpertz, S., Ehrlich, S., van Elburg, A. A., Adan, R. A. H., Scherag, S., Hinney, A., Hebebrand, J., Boomsma, D. I., van Furth, E. F. and Slagboom, P. E. (2011). Association study in eating disorders: TPH2 associates with anorexia nervosa and self-induced vomiting. Genes, Brain and Behavior, 10 (2), 236-243. doi: 10.1111/j.1601-183X.2010.00660.x
Bartels, Meike, van de Aa, Niels, van Beijsterveldt, Catherina E. M., Middeldorp, Christel M. and Boomsma, Dorret I. (2011). Adolescent self-report of emotional and behavioral problems: interactions of genetic factors with sex and age. Canadian Academy of Child and Adolescent Psychiatry, 20 (1), 35-52.
van Beijsterveldt, Catherina E. M., Middeldorp, Christel M., Landt, Margarita C. T. Slof-Op't, Bartels, Meike, Hottenga, Jouke-Jan, Suchiman, H. Eka D., Slagboom, P. Eline and Boomsma, Dorret I. (2011). Influence of candidate genes on attention problems in children: a longitudinal study. Behavior Genetics, 41 (1), 155-164. doi: 10.1007/s10519-010-9406-5
Kendler, Kenneth S., Eaves, Lindon J., Loken, Erik K., Pedersen, Nancy L., Middeldorp, Christel M., Reynolds, Chandra, Boomsma, Dorret, Lichtenstein, Paul, Silberg, Judy and Gardner, Charles O. (2011). The impact of environmental experiences on symptoms of anxiety and depression across the life span. Psychological Science, 22 (10), 1343-1352. doi: 10.1177/0956797611417255
Demirkan, A., Phenninx, B. W. J. H., Hek, K., Wray, N. R., Amin, N., Aulchenko, Y. S., van Dyck, R., de Geus, E. J. C., Hofman, A., Uitterlanden, A. G., Hottenga, J.-J., Nolen, W. A., Oostra, B. A., Sullivan, P. F., Willemsen, G., Zitman, F. G., Tiemeier, H., Janssens, A. C. J. W., Boomsma, D. I., van Duijn, C. M. and Middeldorp, C. M. (2011). Genetic risk profiles for depression and anxiety in adult and elderly cohorts. Molecular Psychiatry, 16 (7), 773-783. doi: 10.1038/mp.2010.65
Middeldorp, C. M., de Moor, M. H. M., McGrath, L. M., Gordon, S. D., Blackwood, D. H., Costa, P. T., Terracciano, A., Krueger, R. F., de Geus, E. J. C., Nyholt, D. R., Tanaka, T., Esko, T., Madden, P. A. F., Derringer, J., Amin, N., Willemsen, G., Hottenga, J-J., Distel, M. A., Uda, M., Sanna, S., Spinhoven, P., Hartman, C. A, Ripke, S., Sullivan, P. F., Realo, A., Allik, J., Heath, A. C., Pergadia, M. L., Agrawal, A. ... Boomsma, D. I. (2011). The genetic association between personality and major depression or bipolar disorder. A polygenic score analysis using genome-wide association data. Translational Psychiatry, 1 (10) e50, e50.1-e50.8. doi: 10.1038/tp.2011.45
Perlis, Roy H., Huang, Jie, Purcell, Shaun, Fava, Maurizio, Rush, A. John, Sullivan, Patrick F., Hamilton, Steven P., McMahon, Francis J., Schulze, Thomas, Potash, James B., Zandi, Peter P., Willour, Virginia L., Penninx, Brenda W., Boomsma, Dorret I., Vogelzangs, Nicole, Middeldorp, Christel M., Rietschel, Marcella, Noethen, Markus, Cichon, Sven, Gurling, Hugh, Bass, Nick, McQuillin, Andrew, Hamshere, Marian, Craddock, Nick, Sklar, Pamela and Smoller, Jordan W. (2010). Genome-wide association study of suicide attempts in mood disorder patients. American Journal of Psychiatry, 167 (12), 1499-1507. doi: 10.1176/appi.ajp.2010.10040541
Middeldorp, Christel M., de Geus, Eco J. C., Willemsen, Gonneke, Hottenga, Jouke-Jan, Slagboom, P. Eline and Boomsma, Dorret I. (2010). The serotonin transporter gene length polymorphism (5-HTTLPR) and life events: no evidence for an interaction effect on neuroticism and anxious depressive symptoms. Twin Research and Human Genetics, 13 (6), 544-549. doi: 10.1375/twin.13.6.544
Middeldorp, C. M., Slof-Op 't Landt, M. C. T., Medland, S. E., van Beijsterveldt, C. E. M., Bartels, M., Willemsen, G., Hottenga, J. -J., de Geus, E. J. C., Suchiman, H. E. D., Dolan, C. V., Neale, M. C., Slagboom, P. E. and Boomsma, D. I. (2010). Anxiety and depression in children and adults: influence of serotonergic and neurotrophic genes?. Genes, Brain and Behavior, 9 (7), 808-816. doi: 10.1111/j.1601-183X.2010.00619.x
Lamb, Diane J., Middeldorp, Christel M., van Beijsterveldt, Catarina E. M., Bartels, Meike, van der Aa, Niels, Polderman, Tinca J. C. and Boomsma, Dorret I. (2010). Heritability of Anxious-Depressive and Withdrawn Behavior: Age-Related Changes During Adolescence. Journal of the American Academy of Child and Adolescent Psychiatry, 49 (3), 248-255. doi: 10.1016/j.jaac.2009.11.014
Franic, Sanja, Middeldorp, Christel M., Dolan, Conor V., Ligthart, Lannie and Boomsma, Dorret I. (2010). Childhood and adolescent anxiety and depression: Beyond heritability. Journal of the American Academy of Child and Adolescent Psychiatry, 49 (8), 820-829. doi: 10.1016/j.jaac.2010.05.013
Middeldorp, Christel M., Vink, Jacqueline M., Hettema, John M., de Geus, Eco J. C., Kendler, Kenneth S., Willemsen, Gonneke, Neale, Michael C., Boomsma, Dorret I. and Chen, Xiangning (2010). An association between Epac-1 gene variants and anxiety and depression in two independent samples. American Journal of Medical Genetics Part B-Neuropsychiatric Genetics, 153 (1), 214-219. doi: 10.1002/ajmg.b.30976
Swets, M., Middeldorp, C. M. and Schoevers, R. A. (2009). Heritability and environment in psychiatric disorders Erfelijkheid en omgevingsinvloeden bij psychiatrische stoornissen. Tijdschrift voor Psychiatrie, 51 (9), 651-663.
Middeldorp, C. M. and Boomsma, D. I. (2009). Reaction on 'gene environment interaction: Mechanism of action of early relationshiops?' Reactie op 'de gen-omgevingsinteractie en de psychiatrie: Nieuwe visie op de invloed van de vroege omgeving'. Tijdschrift voor Psychiatrie, 51 (4), 267-268.
Rodger, M. A., Paidas, M., McLintock, C., Middeldorp, C., Kahn, S., Martinelli, I., Hague, W., Montella, K. R. and Greer, I. (2008). Erratum: Inherited thrombophilia and pregnancy complications revisited (Obstetrics & Gynecology (2008) 112 (320-324)). Obstetrics and Gynecology, 112 (6) doi: 10.1097/01.AOG.0000341971.18168.2d
Middeldorp, C. M., Cath, D. C., Beem, A. L., Willemsen, G. and Boomsma, D. I. (2008). Life events, anxious depression and personality: A prospective and genetic study. Psychological Medicine, 38 (11), 1557-1565. doi: 10.1017/S0033291708002985
Middeldorp, CM, Sullivan, PF, Wray, NR, Hottenga, JJ, de Geus, EJC, van den Berg, M, Montgomery, GW, Coventry, WL, Statham, DJ, Andrews, G, Slagboom, PE, Boomsma, DI and Martin, NG (2008). Suggestive linkage on chromosome 2, 8, and 17 for lifetime major depression. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 150B (3), 352-358. doi: 10.1002/ajmg.b.30817
Wray, Naomi R., Middeldorp, Christel M., Birley, Andrew J., Gordon, Scott D., Sullivan, Patrick F., Visscher, Peter M., Nyholt, Dale R, Willemsen, Gonneke, de Geus, Eco J.C., Slagboom, P. Eline, Montgomery, Grant W., Martin, Nicholas G. and Boomsma, Dorret I. (2008). Genome-wide linkage analysis of multiple measures of neuroticism of 2 large cohorts from Australia and the Netherlands. Archives of General Psychiatry, 65 (6), 649-658. doi: 10.1001/archpsyc.65.6.649
Distel, Marijn A., Vink, Jacqueline M., Willemsen, Gonneke, Middeldorp, Christel M., Merckelbach, Harald L. G. J. and Boomsma, Dorret I. (2008). Heritability of self-reported phobic fear. Behavior Genetics, 38 (1), 24-33. doi: 10.1007/s10519-007-9182-z
Shifman, S., Bhomra, A., Smiley, S., Wray, N. R., James, M. R., Martin, N. G., Hettema, J. M., An, S. S., Neale, M. C., van den Oord, E. J., Kendler, K. S., Chen, X., Boomsma, D. I., Middeldorp, C. M., Hottenga, J. J., Slagboom, P. E. and Flint, J. (2008). A whole genome association study of neuroticism using DNA pooling. Molecular Psychiatry, 13 (3), 302-312. doi: 10.1038/sj.mp.4002048
Middeldorp, C. M., Hottenga, J-J, Slagboom, P. E., Sullivan, P. F., de Geus, E. J. C., Posthuma, D., Willemsen, G. and Boomsma, D. I. (2008). Linkage on chromosome 14 in a genome-wide linkage study of a broad anxiety phenotype. Molecular Psychiatry, 13 (1), 84-89. doi: 10.1038/sj.mp.4002061
Middeldorp, Christel M., de Geus, Eco J. C., Beem, A. Leo, Lakenberg, Nico, Hottenga, Jouke-Jan, Slagboom, P. Eline and Boomsma, Dorret I. (2007). Family based association analyses between the serotonin transporter gene polymorphism (5-HTTLPR) and neuroticism, anxiety and depression. Behavior Genetics, 37 (2), 294-301. doi: 10.1007/s10519-006-9139-7
Middeldorp, CM, Cath, DC and Boomsma, DI (2006). A twin-family study of the association between employment, burnout and anxious depression. Journal of Affective Disorders, 90 (2-3), 163-169. doi: 10.1016/j.jad.2005.11.004
Middeldorp, Christel M., Wray, Naomi R., Andrews, Gavin, Martin, Nicholas G. and Boomsma, Dorret I. (2006). Sex Differences in Symptoms of Depression in Unrelated Individuals and Opposite-Sex Twin and Sibling Pairs. Twin Research And Human Genetics, 9 (5), 632-636. doi: 10.1375/183242706778553507
Middledorp, Christel M., Birley, Andrew J., Cath, Danielle C., Gillespie, Nathan A., Willemsen, Gonneke, Statham, Dixie J., de Geus, Eco J. C., Andrews, J. Gavin, van Dyck, Richard, Beem, A. Leo, Sullivan, Patrick F., Martin, Nicholas G. and Boomsma, Dorret I. (2005). Familial clustering of major depression and anxiety disorders in Australian and Dutch twins and siblings. Twin Research and Human Genetics, 8 (6), 609-615. doi: 10.1375/183242705774860123
Middeldorp, CM, Cath, DC, Vink, JM and Boomsma, DI (2005). Twin and genetic effects on life events. Twin Research and Human Genetics, 8 (3), 224-231. doi: 10.1375/1832427054253130
Middeldorp, CM, Cath, DC, Van Dyck, R and Boomsma, DI (2005). The co-morbidity of anxiety and depression in the perspective of genetic epidemiology. A review of twin and family studies. Psychological Medicine, 35 (5), 611-624. doi: 10.1017/S003329170400412X
Middeldorp, CM, Stubbe, JH, Cath, DC and Boomsma, DI (2005). Familial clustering in burnout: A twin-family study. Psychological Medicine, 35 (1), 113-120. doi: 10.1017/S0033291704002983
Vink, JM, Willemsen, G, Stubbe, JH, Middeldorp, CM, Ligthart, RSL, Baas, KD, Dirkzwager, HJC, de Geus, EJC and Boomsma, DI (2004). Estimating non-response bias in family studies: Application to mental health and lifestyle. European Journal of Epidemiology, 19 (7), 623-630. doi: 10.1023/B:EJEP.0000036814.56108.66
Middeldorp, CM, Geerts, AT, Brouwer, TF, Peters, ACB, Stroink, H, van Donselaar, CA and Arts, WFM (2002). Nonsymptomatic generalized epilepsy in children younger than six years: Excellent prognosis, but classification should be reconsidered after follow-up: The Dutch Study of Epilepsy in Childhood. Epilepsia, 43 (7), 734-739. doi: 10.1046/j.1528-1157.2002.72601.x
Conference Papers
Kwong, Alex, Adams, Mark, Wootton, Robyn, Carr, Kevin, Chatiza, Tariro, Middeldorp, Christel and McIntosh, Andrew (2023). Leveraging Genetics to Examine the Causal Role of Adolescent Depression on Later Early Adult Outcomes. World Congress of Psychiatric Genetics (WCPG), Montreal, QC Canada, 10-14 October 2023. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2023.08.133
Thorp, Jackson G., Campos, Adrian I., Grotzinger, Andrew D., Gerring, Zachary, An, Jiyuan, Ong, Jue-Sheng, Wang, Wei, Shringarpure, Suyash, Byrne, Enda M., MacGregor, Stuart, Martin, Nicholas G., Medland, Sarah E., Middeldorp, Christel M. and Derks, Eske M. (2020). Symptom-level genetic modelling identifies novel risk loci and unravels the shared genetic architecture of anxiety and depression. 50th Annual Meeting of the Behavior-Genetics-Association (BGA), Electr Network, Jun 26, 2020. NEW YORK: SPRINGER.
Jami, Eshim, Hammerschlag, Anke, Bartels, Meike and Middeldorp, Christel M. (2019). GENOME-WIDE ASSOCIATION META-ANALYSIS OF CHILDHOOD AND ADOLESCENT INTERNALISING PROBLEMS. 27th World Congress of Psychiatric Genetics (WCPG), Los Angeles Ca, Oct 26-31, 2019. AMSTERDAM: ELSEVIER. doi: 10.1016/j.euroneuro.2019.08.044
Middeldorp, Christel M., Sallis, Hannah and Thapar, Anita (2019). POLYGENIC ANALYSES OF CHILDHOOD PSYCHOPATHOLOGY IN LARGE POPULATION BASED SAMPLES PROVIDE INSIGHT INTO PERSISTENCE OF SYMPTOMS AND THE EFFECTS OF THE (EARLY) ENVIRONMENT. 27th World Congress of Psychiatric Genetics (WCPG), Los Angeles Ca, Oct 26-31, 2019. AMSTERDAM: ELSEVIER. doi: 10.1016/j.euroneuro.2019.07.031
Akingbuwa, Wonuola, Nivard, Michel, Hammerschlag, Anke, Bartels, Meike and Middeldorp, Christel M. (2019). GENE EXPRESSION IN BRAIN CELL TYPES AND BIOLOGICAL FUNCTIONS UNDERLYING NEUROPSYCHIATRIC DISORDERS. 27th World Congress of Psychiatric Genetics (WCPG), Los Angeles Ca, Oct 26-31, 2019. AMSTERDAM: ELSEVIER. doi: 10.1016/j.euroneuro.2019.08.164
Akingbuwa, Wonuola, Bartels, Meike and Middeldorp, Christel M. (2019). Genetic overlap between childhood psychopathology and adult traits. 27th World Congress of Psychiatric Genetics (WCPG), Los Angeles, CA, United States, 26-31 October, 2019. Amsterdam, Netherlands: Elsevier BV. doi: 10.1016/j.euroneuro.2019.07.032
Middeldorp, C. M., Scott, J. G., Tunbridge, M., Stathis, S., Guastella, A. J. and Coghill, D. (2019). Factors influencing the course of mental disorders in childhood and beyond. RANZCP 2019 Congress, Cairns Convention Centre, 12-16 May 2019. London, United Kingdom: Sage Publications.
Middeldorp, C. M., Akingbuwa, O., Jarvelin, M. -R., Lichtenstein, P., Lundstrom, S., Munafo, M., Plomin, R., Tiemeier, H., Ystrom, E. and Bartels, M. (2019). Do shared genetic factors explain the prediction of bipolar disorder by childhood psychiatric symptoms?. 21st Annual ISBD Conference on Global Advances in Bipolar Disorder and Depression, Sydney, Australia, 20-23 March, 2019. Hoboken, NJ, United States: Wiley-Blackwell Publishing. doi: 10.1111/bdi.06_12743
Middeldorp, C. M. (2019). The course of childhood psychopathology: the role of genetic factors and the association with parental symptoms. RANZCP 2019 Congress, Cairns Convention Centre, 12-16 May 2019. London, United Kingdom: Sage Publications.
Shahid, Eshim, Eilertsen, Espen, Hammerschlag, Anke, Sallis, Hannah, Qiao, Zhen, Evans, David, Ystrom, Eivind, Bartels, Meike and Middeldorp, Christel M. (2019). Maternal and paternal effects on offspring internalising problems: findings from family data and extended GCTA analyses. 27th World Congress of Psychiatric Genetics (WCPG), Los Angeles, CA, United States, 26-31 October, 2019. Amsterdam, Netherlands: Elsevier BV. doi: 10.1016/j.euroneuro.2019.07.034
Hammerschlag, Anke, Byrne, Enda, Bartels, Meike, Wray, Naomi and Middeldorp, Christel M. (2019). Integrative analysis of genome-wide association study results of attention-deficit/hyperactivity disorder (ADHD) and human fetal brain methylation data reveals novel genes associated with ADHD. 26th World Congress of Psychiatric Genetics (WCPG), Glasgow, Scotland, 11-15 October 2018. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2018.08.063
Ensink, Judith, Keding, Taylor J., Henneman, Peter, Zantvoord, Jasper, Middeldorp, Christel M., Mannens, Marcel M. A. M., Herringa, Ryan J. and Lindauer, Ramon J. L. (2019). Genome-wide DNA methylation differences and their relationship with neural abnormalities in youth with and without posttraumatic stress disorder. 26th World Congress of Psychiatric Genetics (WCPG), Glasgow, Scotland, 11-15 October 2018. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2018.08.180
Grasby, Katrina, Colodro-Conde, Lucia, Morosoli, Jose J., Middeldorp, Christel, van Beijsterveldt, Toos, Boomsma, Dorret, Martin, Nicholas, Bartels, Meike and Medland, Sarah (2019). A cross-country, cross-reporter twin study of oppositional defiant disorder. 49th Annual Meeting of the Behavior Genetics Association (BGA), Stockholm, Sweden, 26-29 June, 2019. New York, NY, United States: Springer New York LLC. doi: 10.1007/s10519-019-09973-8
Middeldorp, Christel M., Akingbuwa, Omowonuola, Jarvelin, Marjo-Riitta, Lichtenstein, Paul, Lundstrom, Sebastian, Kuja-Halkola, Ralf, Munafo, Marcus, Plomin, Robert, Rimfeld, Kaili, Sallis, Hannah, Tiemeier, Henning, Ystrom, Eivind and Bartels, Meike (2019). The value of polygenic risk scores in predicting the transition from childhood and adolescent psychiatric symptoms into chronic adult psychopathology. 26th World Congress of Psychiatric Genetics (WCPG), Glasgow, Scotland, 11-15 October 2018. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2018.08.455
Coghill, D. and Middeldorp, C. (2019). Clinical update: recent advances in attention-deficit hyperactivity disorder. RANZCP 2019 Congress, Cairns Convention Centre, 12-16 May 2019. London, United Kingdom: Sage Publications.
Middeldorp, Christel M., Drevets, Wayne, Jarvelin, Marjo-Riitta, Lichtenstein, Paul, Lundstrom, Sebastian, Munafo, Marcus, Plomin, Robert, Tiemeier, Henning, van den Berg, Stephanie M., Fanos, Vassilios and Bartels, Meike (2019). M73 - Capice: childhood and adolescence psychopathology: unravelling the complex etiology by a large interdisciplinary collaboration in Europe. 25th World Congress of Psychiatric Genetics (WCPG), Orlando, FL, United States, 13-17 October 2017. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2017.08.380
Wesseldijk, Laura, Fedko, Iryna, Bartels, Meike, Nivard, Michel, Hottenga, Jouke-Jan, van Beijsterveldt, Catherina, Boomsma, Dorret and Middeldorp, Christel (2016). Differences in maternal and paternal ratings of psychopathology and the genetic epidemiology in 12,000 7-year old twin pairs. 46th Annual Meeting of the Behavior-Genetics-Association, Brisbane, Australia, Jun 20-23, 2016. NEW YORK: SPRINGER.
Conde, Lucia Colodro, Martin, Nicholas, Hatemi, Peter, Boomsma, Dorret, Middeldorp, Christel, van Beijsterveldt, Toos, Bartels, Meike and Medland, Sarah (2016). Heritability of different aggression phenotypes in an Australian and a Dutch cohort. 46th Annual Meeting of the Behavior-Genetics-Association, Brisbane, Australia, Jun 20-23, 2016. NEW YORK: SPRINGER.
Porsch, Robert, Middeldorp, Christel, Cherny, Stacey, Krapohl, Eva, van Beijsterveldt, Catherina, Loukola, Anu, Korhonen, Tellervo, Pulkkinen, Lea, Corley, Robin, Rhee, Soo, Kaprio, Jaakko, Rose, Richard, Hewitt, John, Sham, Pak, Plomin, Robert, Boomsma, Dorret and Bartels, Meike (2016). A cross-cultural comparison of the longitudinal heritability of childhood aggression. 46th Annual Meeting of the Behavior-Genetics-Association, Brisbane, Australia, Jun 20-23, 2016. NEW YORK: SPRINGER.
Bot, M., Middeldorp, C., de Geus, E., Lau, H. M., Sinke, M., van Nieuwenhuizen, B., Smit, J., Boomsma, D. and Penninx, B. (2016). Self-reported online assessment of lifetime major depressive disorder: a validation study. 18th Annual Conference of the International-Society-for-Bipolar-Disorders / 8th Biennial Conference of the International-Society-for-Affective-Disorders, Amsterdam, Netherlands, Jul 13-16, 2016. HOBOKEN: WILEY-BLACKWELL.
Walters, Raymond, Mattheisen, Manuel, Demontis, Ditte, Daly, Mark, Borglum, Anders, Faraone, Stephen, Middeldorp, Christel, Boomsma, Dorret and Neale, Benjamin (2016). Integrating GWAS of ADHD and continuous ADHD-related traits. 46th Annual Meeting of the Behavior-Genetics-Association, Brisbane, Australia, Jun 20-23, 2016. NEW YORK: SPRINGER.
Nivard, Michel, Middeldorp, Christel, Hottenga, Jouke-Jan, Fedko, Iryna, Ehli, Erik, Davies, Gareth, van Beijsterveldt, Catherina, Bartels, Meike and Boomsma, Dorret (2016). Multivariate and repeated measure GWAS of aggression phenotypes. 46th Annual Meeting of the Behavior-Genetics-Association, Brisbane, Australia, Jun 20-23, 2016. NEW YORK: SPRINGER.
Miller, Patrick, Verhulst, Brad, Bartels, Meike, van Beijsterveldt, Toos, Willemsen, Gonneke, Boomsma, Dorret, Middeldorp, Christel and Lubke, Gitta (2015). Choosing a powerful depression phenotype: trajectories of anxiety and depression between age 7 and age 18 and the influence of genetic factors in Dutch twins. 45th Annual Meeting of the Behavior-Genetics-Association, San Diego Ca, Jun 20, 2015. NEW YORK: SPRINGER.
Nivard, Michel, Dolan, Conor, Peyrot, Wouter, Abdellaoui, Abdel, Hottenga, Jouke-Jan, Middeldorp, Christel and Boomsma, Dorret (2015). Rapid genetic (co) variance estimation based on measured SNPs applied to item level data. 45th Annual Meeting of the Behavior-Genetics-Association, San Diego Ca, Jun 20, 2015. NEW YORK: SPRINGER.
Boomsma, Dorret, van den Berg, Stephanie, Abdellaoui, Abdel, de Geus, Eco, Willemsen, Gonneke, Hottenga, Jouke-Jan, Middeldorp, Christel, Milaneschi, Yuri, Nivard, Michel, Vink, Jacqueline, Bartels, Meike, Van Grootheest, Gerard, Penninx, Brenda and de Moor, Marleen (2015). Prediction from polygenic scores based on GWA of Neuroticism to psychiatric and lifestyle traits. 45th Annual Meeting of the Behavior-Genetics-Association, San Diego Ca, Jun 20, 2015. NEW YORK: SPRINGER.
Lindauer, R., Brilleslijper-kater, S., Diehle, J., Verlinden, E., Teeuw, A., Middeldorp, C., Tuinebreijer, W., Bosschaart, T., Van Duin, E. and Verhoeff, A. (2015). The Amsterdam sexual abuse case (ASAC)-study in day care centers: longitudinal effects of sexual abuse on infants and very young children and their parents, and the consequences of the persistence of abusive images on the internet. SPRINGER.
Middeldorp, Christel, Groen-Blokhuis, Maria, Hottenga, Jouke Jan, Scheet, Paul, Nivard, Michel, van Beijsterveldt, Toos, Bartels, Meike, Vink, Jacqueline, de Geus, Eco, Willemsen, Gonneke, Hudziak, Jim and Boomsma, Dorret (2012). Are symptoms of anxiety and depression during childhood and adolescence influenced by similar genetic factors as major depression in adulthood?. 42nd Annual Meeting of the Behavior-Genetics-Association, Edinburgh Scotland, Jun 22-25, 2012. SPRINGER.
Lamb, Diane, Middeldorp, Christel, Vink, Jacqueline, van Beijsterveldt, Toos, Lindauer, Ramon and Boomsma, Dorret (2012). Short and long-term effects of nonparental child care on internalizing and externalizing problems: A behavior genetic study in Dutch twins. 42nd Annual Meeting of the Behavior-Genetics-Association, Edinburgh Scotland, Jun 22-25, 2012. SPRINGER.
Groen-Blokhuis, Maria, de Graaff, Jurgen, Bartels, Meike, Duran, Maryse, van Beijsterveldt, Toos, Kalkman, Cor, Middeldorp, Christel and Boomsma, Dorret (2012). The influence of early anesthesia exposure on ADHD. 42nd Annual Meeting of the Behavior-Genetics-Association, Edinburgh Scotland, Jun 22-25, 2012. SPRINGER.
Abdellaoui, Abdel, Bartels, Meike, Boomsma, Dorret, Davies, Gareth, Dolan, Conor, Geels, Lot, Groen-Blokhuis, Maria, Hottenga, Jouke Jan, Kendler, Kenneth, Middeldorp, Christel, Nivard, Michel, Scheet, Paul, Sullivan, Patrick, van Beek, Jenny, van Beijsterveldt, Toos and Willemsen, Gonneke (2012). Stability and change in anxious depression as a function of genes and environment. A longitudinal twin and GWA study from age 3 to 65 years. 42nd Annual Meeting of the Behavior-Genetics-Association, Edinburgh Scotland, Jun 22-25, 2012. SPRINGER.
Breen, Gerome, Alsabban, Shaza, Nivard, Michel and Middeldorp, Christel (2012). What have modern genetic studies told us about depression?. 42nd Annual Meeting of the Behavior-Genetics-Association, Edinburgh Scotland, Jun 22-25, 2012. SPRINGER.
Nivard, Michel, van der Sluis, Sophie, Franic, Sanja, Cramer, Angelique, Visser, Ingmar, Middeldorp, Christel, Lubke, Gitta, Boomsma, Dorret and Borsboom, Denny (2012). Phenotypic complexity as genetic dark matter: A network explanation of missing heritability. 42nd Annual Meeting of the Behavior-Genetics-Association, Edinburgh Scotland, Jun 22-25, 2012. SPRINGER.
Distel, Marijn A., Middeldorp, Christel M., Willemsen, Gonneke, Trull, Timothy J., Derom, Catherine A. and Boomsma, Dorret I. (2009). Life events and borderline personality disorder. 39th Annual Meeting of the Behavior-Genetics-Association, Mineapolis Mn, Jun 17-20, 2009. SPRINGER.
Middeldorp, Christel, Hottenga, Jouke Jan, Slagboom, P. Eline, Sullivan, Patrick F., Beem, A. Leo, Willemsen, Gonneke and Boomsma, Dorret I. (2006). Significant linkage on chromosome 14 for anxiety. 14th World Congress on Psychiatric Genetics, Cagliari Italy, Oct 28-Nov 01, 2006. WILEY-LISS.
Middeldorp, CM, Cath, DC, Beem, AL and Boomsma, DI (2004). Genetic epidemiology of depression in a selected population of Dutch twins and their siblings. 34th Annual Meeting of the Behavior-Genetics-Association, Aix en Provence France, Jun 27-30, 2004. SPRINGER.
Middeldorp, CM, Ruigrok, P, Cath, DC, Van Dyck, R and Boomsma, DI (2002). Candidate genes for mood disorders in humans. A literature review. 10th World Congress of Psychiatric Genetics, Brussels Belgium, Oct 09-13, 2002. WILEY-LISS.