Honorary Professor Luregn Schlapbach
Professor, Honorary
Child Health Research Centre
Journal Articles
He, Jingni, Ganesamoorthy, Devika, Chang, Jessie J.-Y., Zhang, Jianshu, Trevor, Sharon L., Gibbons, Kristen S., McPherson, Stephen J., Kling, Jessica C., Schlapbach, Luregn J., Blumenthal, Antje, Coin, Lachlan J. M., RAPIDS Study Group and Irwin, Adam (2025). Utilizing Nanopore direct RNA sequencing of blood from patients with sepsis for discovery of co- and post-transcriptional disease biomarkers. BMC Infectious Diseases, 25 (1) 692, 1-19. doi: 10.1186/s12879-025-11078-z
Tu, Quyen, Won, Hayoung, Sime, Fekade Bruck, Raman, Sainath, Cotta, Menino Osbert, Wallis, Steven C., Marjanovic, Dusan, Stacey, Sonya, Schlapbach, Luregn and Roberts, Jason A. (2025). The FUSION Study: compatibility of antibiotics with commonly used medication infusions in a paediatric intensive care unit. European Journal of Hospital Pharmacy ejhpharm-2024-004450, ejhpharm-2024. doi: 10.1136/ejhpharm-2024-004450
Irwin, Adam D., Graham, Nicolette, Gartrell, Kyana, Fletchett, Emily, Cross, Jack, Doyle, Kayla, Owen, Kieran, Seaton, Robert, Rice, Michael, Lane, Paul, Ergetu, Endrias, Gilholm, Patricia, Gibbons, Kristen S., Raman, Sainath, Harley, Amanda, Lister, Paula, Grimwood, Keith, Schlapbach, Luregn J., on behalf of the Queensland Statewide Sepsis Collaborative, Redpath, Lyndell, Mason, Donna, Kalke, Vikrant, Mehta, Naitik, Taylor, Scott and Bell, Anna (2025). Impact of a statewide sepsis pathway on quality of antibiotic use in children in the Emergency Department. Intensive Care Medicine – Paediatric and Neonatal, 3 (1) 11, 1-10. doi: 10.1007/s44253-025-00060-x
Kennedy, Uchenna K., Moulin, Juliette, Buhrer, Lea, Nian, Joanne Lim Fang, Halter, Leyla, Bohni, Luzius, Guzelgun, Melisa, Menon, Kusum, Lee, Jan Hau, Schlapbach, Luregn J. and Held, Ulrike (2025). Sex Differences in Pediatric Sepsis Mortality: A Systematic Review and Meta-Analysis. Critical Care Explorations, 7 (4) e1226, e1226. doi: 10.1097/CCE.0000000000001226
Gilholm, Patricia, Raman, Sainath, Irwin, Adam, Lister, Paula, Harley, Amanda, Schlapbach, Luregn J. and Gibbons, Kristen S. (2025). Identification of distinct clinical profiles of sepsis risk in paediatric emergency department patients using Bayesian profile regression. BMJ Paediatrics Open, 9 (1) e003100, e003100-1. doi: 10.1136/bmjpo-2024-003100
George, Shane, Williams, Tara, Humphreys, Susan, Atkins, Tiffany, Tingay, David, Gelbart, Ben, Pham, Trang, Craig, Simon, Erickson, Simon, Chavan, Arjun, Rasmussen, Katie, Ganeshalingham, Anusha, Oberender, Felix, Ganu, Subodh, Singhal, Nitesh, Gibbons, Kristen, Le Marsney, Renate, Burren, Juerg, Schlapbach, Luregn J., Gannon, Brenda, Jones, Mark, Dalziel, Stuart R and Schibler, Andreas (2025). Effectiveness of nasal high-flow oxygen during apnoea on hypoxaemia and intubation success in paediatric emergency and ICU settings: a randomised, controlled, open-label trial. The Lancet Respiratory Medicine. doi: 10.1016/s2213-2600(25)00074-8
Taneri, Petek Eylul, Biesty, Linda, Kirkham, Jamie J., Molloy, Eleanor J., Polin, Richard A., Branagan, Aoife, Kawaza, Kondwani, Daly, Mandy, Wynn, James L., Nagy Bonnard, Lívia, Quirke, Fiona A., Kissoon, Niranjan, Ohaja, Magdalena, Bazilio, Kateregga, Giannoni, Eric, Schlapbach, Luregn J., Suguitani, Denise, Strunk, Tobias, Stoll, Barbara J. and Devane, Declan (2025). Proposed Core Outcomes After Neonatal Sepsis : A Consensus Statement. JAMA Network Open, 8 (2) e2461554, e2461554. doi: 10.1001/jamanetworkopen.2024.61554
Viz-Lasheras, Sandra, Gómez-Carballa, Alberto, Pardo-Seco, Jacobo, Bello, Xabier, Rivero-Calle, Irene, Dacosta, Ana Isabel, Kaforou, Myrsini, Habgood-Coote, Dominic, Cunnington, Aubrey J., Emonts, Marieke, Herberg, Jethro A., Wright, Victoria J., Carrol, Enitan D., Paulus, Stephane C., Zenz, Werner, Kohlfürst, Daniela S., Van der Flier, Michiel, de Groot, Ronald, Schlapbach, Luregn J., Agyeman, Philipp, Pollard, Andrew J., Fink, Colin, Kuijpers, Taco T., Anderson, Suzanne, Calvo, Cristina, Martínez-Padilla, María del Carmen, Pérez-Aragón, Ana, Gómez-Sánchez, Esteban, Valencia-Ramos, Juan ... Salas, Antonio (2025). A 5-transcript signature for discriminating viral and bacterial etiology in pediatric pneumonia. iScience, 28 (2) 111747, 111747-2. doi: 10.1016/j.isci.2025.111747
Bottari, Gabriella, Buccione, Emanuele, Bayrakci, Benan, Briassoulis, George, Carter, Michael J., Demirkol, Demet, Ilia, Stavroula, Morin, Luc, Reiter, Karl, Santiago, Maria-Jose, Schlapbach, Luregn J., Slocker-Barrio, Maria, Tissieres, Pierre, Zaoral, Tomás, Bianzina, Stefania and Deep, Akash (2025). Extracorporeal Blood Purification in European Pediatric Intensive Care Units : A Consensus Statement. JAMA Network Open, 8 (2) e2457657, e2457657-2. doi: 10.1001/jamanetworkopen.2024.57657
Asperen, Roelie M Wösten-van, Hines, Melissa R, Schlapbach, Luregn J and Agulnik, Asya (2025). Tailoring organ dysfunction criteria for critically ill children with cancer. The Lancet Child & Adolescent Health, 9 (4), 217-219. doi: 10.1016/s2352-4642(24)00305-5
Wösten-van Asperen, Roelie M., la Roi-Teeuw, Hannah M., Tissing, Wim J.E., Jordan, Iolanda, Dohna-Schwake, Christian, Bottari, Gabriella, Pappachan, John, Crazzolara, Roman, Amigoni, Angela, Mizia-Malarz, Agnieszka, Moscatelli, Andrea, Sánchez-Martín, María, Willems, Jef, Schlapbach, Luregn J. and on behalf of PICU Oncology Kids in Europe Research (POKER) group research consortium of European Society for Paediatric and Neonatal Intensive Care (ESPNIC) (2025). The Phoenix Sepsis Score in Pediatric Oncology Patients With Sepsis at PICU Admission: Test of Performance in a European Multicenter Cohort, 2018–2020. Pediatric Critical Care Medicine, 26 (2), e177-e185. doi: 10.1097/pcc.0000000000003683
Watson, R. Scott, Argent, Andrew C., Sorce, Lauren R., Randolph, Adrienne G., Sanchez-Pinto, L. Nelson, Bennett, Tellen D., Kissoon, Niranjan, Schlapbach, Luregn J. and on behalf of the Society of Critical Care Medicine Pediatric Sepsis Definition Taskforce (2025). The 2024 Phoenix Sepsis Score Criteria: Part 1, the Evolution in Definition of Sepsis and Septic Shock. Pediatric Critical Care Medicine, 26 (2), e246-e251. doi: 10.1097/pcc.0000000000003664
Gilholm, Patricia, Lister, Paula, Irwin, Adam, Harley, Amanda, Raman, Sainath, Schlapbach, Luregn J. and Gibbons, Kristen S. (2025). Comparison of Random Forest and Stepwise Regression for Variable Selection Using Low Prevalence Predictors: A case Study in Paediatric Sepsis. Maternal and Child Health Journal, 29 (5), 1-10. doi: 10.1007/s10995-025-04038-1
Viz-Lasheras, Sandra, Gómez-Carballa, Alberto, Bello, Xabier, Rivero-Calle, Irene, Dacosta, Ana Isabel, Kaforou, Myrsini, Habgood-Coote, Dominic, Cunnington, Aubrey J., Emonts, Marieke, Herberg, Jethro A., Wright, Victoria J., Carrol, Enitan D., Paulus, Stephane C., Zenz, Werner, Kohlfürst, Daniela S., Schweintzger, Nina, Van der Flier, Michiel, de Groot, Ronald, Schlapbach, Luregn J., Agyeman, Philipp, Pollard, Andrew J., Fink, Colin, Kuijpers, Taco T., Anderson, Suzanne, Von Both, Ulrich, Pokorn, Marko, Zavadska, Dace, Tsolia, María, Moll, Henriëtte A ... Salas, Antonio (2025). A diagnostic host-specific transcriptome response for Mycoplasma pneumoniae pneumonia to guide pediatric patient treatment. Nature communications, 16 (1) 673, 1. doi: 10.1038/s41467-025-55932-9
Mozun, Rebeca, Chopard, Daphné, Zapf, Florian, Baumann, Philipp, Brotschi, Barbara, Adam, Anika, Jaeggi, Vera, Bangerter, Beat, Gibbons, Kristen S., Burren, Juerg and Schlapbach, Luregn J. (2025). Comparison of carbon dioxide control during pressure controlled versus pressure-regulated volume controlled ventilation in children (CoCO2): protocol for a pilot digital randomised controlled trial in a quaternary paediatric intensive care unit. BMJ Open, 15 (1) e087043, 1-9. doi: 10.1136/bmjopen-2024-087043
Gibbons, Kristen S., Beca, John, Delzoppo, Carmel, Erickson, Simon, Festa, Marino, Gelbart, Ben, Long, Debbie, Masterson, Kate, Millar, Johnny, Raman, Sainath, Schlapbach, Luregn J., Butt, Warwick and on behalf of the Australian and New Zealand Intensive Care Society Paediatric Study Group (ANZICS PSG) (2025). The Australian and New Zealand Intensive Care Society Paediatric Study Group (ANZICS PSG): 20 years of collaborative research. Pediatric Critical Care Medicine, 26 (1), e122-e130. doi: 10.1097/pcc.0000000000003653
Raman, Sainath, Gibbons, Kristen S., Jayashree, Muralidharan, Lalitha, AV, Bellomo, Rinaldo, Blythe, Robin, Buckley, David, Butt, Warwick, Cho, Hwa Jin, Cree, Michele, de Souza, Daniela C., Erickson, Simon, Festa, Marino, Ganu, Subodh, George, Shane, James, Ebor Jacob, Johnson, Kerry, Le Marsney, Renate, Lister, Paula, Pham, Trang M. T., Singh, Puneet, Venkatesh, Balasubramanian, Wall, Renee, Long, Debbie A., Schlapbach, Luregn J. and on behalf of the Resuscitation in Paediatric Septic Shock using Vitamin C and Hydrocortisone (RESPOND) Study Group and the Australian and New Zealand Intensive Care Society Paediatric Study Group (ANZICS PSG) (2024). Resuscitation in Paediatric Septic Shock Using Vitamin C and Hydrocortisone (RESPOND): the RESPOND Randomized Controlled Trial Protocol. Pediatric Critical Care Medicine, 26 (3), 1-12. doi: 10.1097/pcc.0000000000003674
Schöbi, Nina, Sanchez, Carlos, Atkinson, Andrew, Andre, Maya C., Blanchard-Rohner, Geraldine, Perez, Maria-Helena, Trück, Johannes, Welzel, Tatjana, Schlapbach, Luregn J., Bielicki, Julia and Grazioli, Serge (2024). Mental health in children admitted with paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS): a follow-up study at 6 months of the Swissped-RECOVERY trial. Intensive Care Medicine – Paediatric and Neonatal, 2 (1) 34, 1-9. doi: 10.1007/s44253-024-00057-y
Schlapbach, Luregn J, Ramnarayan, Padmanabhan, Gibbons, Kristen S, Morrow, Brenda M, Napolitano, Natalie, Tume, Lyvonne N, Argent, Andrew C, Deep, Akash, Lee, Jan Hau, Peters, Mark J, Agus, Michael S D, Appiah, John Adabie, Armstrong, Jennifer, Bacha, Tigist, Butt, Warwick, de Souza, Daniela Carla, Fernández-Sarmiento, Jaime, Flori, Heidi R, Fontela, Patricia, Gelbart, Ben, González-Dambrauskas, Sebastián, Ikeyama, Takanari, Jabornisky, Roberto, Jayashree, Muralidharan, Kazzaz, Yasser M, Kneyber, Martin C J, Long, Debbie, Njirimmadzi, Jenala, Samransamruajkit, Rujipat ... Menon, Kusum (2024). Building global collaborative research networks in paediatric critical care: a roadmap. The Lancet Child & Adolescent Health, 9 (2), 138-150. doi: 10.1016/s2352-4642(24)00303-1
Muff, Rafael, Gotta, Verena, Jaeggi, Vera, Schlapbach, Luregn J. and Baumann, Philipp (2024). Serum sodium concentration during arginine vasopressin infusion in critically ill children. Children, 11 (11) 1359, 1-10. doi: 10.3390/children11111359
Cree, Michele L., Abdul-Aziz, Mohd Hafiz, Schlapbach, Luregn J., Roberts, Jason A. and Parker, Suzanne (2024). The impact of extracorporeal support on antimicrobial pharmacokinetics in critically ill neonatal and paediatric patients: a systematic review. International Journal of Antimicrobial Agents, 64 (4) 107311, 1-16. doi: 10.1016/j.ijantimicag.2024.107311
Wen, Sophie C. H., Harris, Patrick N. A., Forde, Brian, Permana, Budi, Chatfield, Mark D., Lau, Colleen L., Spurling, Geoffrey, Bauer, Michelle J., Balch, Ross, Chambers, Henry, Schlapbach, Luregn J., Clark, Julia E., Dougherty, Sonia, Blyth, Christopher C., Britton, Philip N., Clifford, Vanessa, Haeusler, Gabrielle M., McMullan, Brendan, Wadia, Ushma, Paterson, David L., Irwin, Adam D., on behalf of the PAEDS network, Carr, Jeremy, Vasilunas, Nan, Francis, Joshua R., Macartney, Kristine, Crawford, Nigel W., Wood, Nicholas, Buttery, Jim ... Glover, Catherine (2024). Characterization of gram-negative bloodstream infections in hospitalised Australian children and their clinical outcomes. Clinical Infectious Diseases, 79 (3), 734-743. doi: 10.1093/cid/ciae341
Raman, Sainath, Gibbons, Kristen, LeMarsney, Renate and Schlapbach, Luregn J. (2024). The authors reply:. Pediatric Critical Care Medicine, 25 (9), e398-e399. doi: 10.1097/pcc.0000000000003578
de Souza, Daniela C., Paul, Raina, Mozun, Rebeca, Sankar, Jhuma, Jabornisky, Roberto, Lim, Emma, Harley, Amanda, Al Amri, Samirah, Aljuaid, Maha, Qian, Suyun, Schlapbach, Luregn J., Argent, Andrew and Kissoon, Niranjan (2024). Quality improvement programmes in paediatric sepsis from a global perspective. The Lancet Child and Adolescent Health, 8 (9), 695-706. doi: 10.1016/S2352-4642(24)00142-1
Watson, R. Scott, Carrol, Enitan D., Carter, Michael J., Kissoon, Niranjan, Ranjit, Suchitra and Schlapbach, Luregn J. (2024). The burden and contemporary epidemiology of sepsis in children. The Lancet Child and Adolescent Health, 8 (9), 670-681. doi: 10.1016/S2352-4642(24)00140-8
Carter, Michael J., Carrol, Enitan D., Ranjit, Suchitra, Mozun, Rebeca, Kissoon, Niranjan, Watson, R. Scott and Schlapbach, Luregn J. (2024). Susceptibility to childhood sepsis, contemporary management, and future directions. The Lancet Child and Adolescent Health, 8 (9), 682-694. doi: 10.1016/S2352-4642(24)00141-X
Sanchez-Pinto, L. Nelson, del Pilar Arias López, María, Scott, Halden, Gibbons, Kristen, Moor, Michael, Watson, R. Scott, Wiens, Matthew O., Schlapbach, Luregn J. and Bennett, Tellen D. (2024). Digital solutions in paediatric sepsis: current state, challenges, and opportunities to improve care around the world. The Lancet Digital Health, 6 (9), e651-e661. doi: 10.1016/s2589-7500(24)00141-9
Kennedy, Uchenna, Moulin, Juliette, Schlapbach, Luregn J., Menon, Kusum, Lee, Jan Hau and Held, Ulrike (2024). Sex differences in pediatric sepsis—a systematic review protocol. Systematic Reviews, 13 (1) 214, 1-5. doi: 10.1186/s13643-024-02631-z
Giannoni, Eric, Sanchez Sanchez, Guillem, Verdebout, Isoline, Papadopoulou, Maria, Rezwani, Moosa, Ahmed, Raya, Ladell, Kristin, Miners, Kelly L., McLaren, James E., Fraser, Donald J., Price, David A., Eberl, Matthias, Agyeman, Philipp K. A., Schlapbach, Luregn J and Vermijlen, David (2024). Sepsis shapes the human γδ TCR repertoire in an age- and pathogen-dependent manner. European Journal of Immunology, 54 (10) 2451190. doi: 10.1002/eji.202451190
Fenner, Anica, Huber, Melanie, Gotta, Verena, Jaeggi, Vera, Schlapbach, Luregn J. and Baumann, Philipp (2024). Antibiotic exposure of critically ill children at a tertiary care paediatric intensive care unit in Switzerland. Children, 11 (6) 731. doi: 10.3390/children11060731
Luethi, Nora, Schlapbach, Luregn J. and Baumann, Philipp (2024). The quest for evidence on time to antibiotics in children with sepsis—finding the sweet spot. JAMA Network Open, 7 (6) e2413926. doi: 10.1001/jamanetworkopen.2024.13926
Watson, R. Scott, Schlapbach, Luregn J., Sorce, Lauren R. and for the Society of Critical Care Medicine Pediatric Sepsis Definitions Task Force (2024). Pediatric Phoenix Sepsis Score validation challenges in low-resource settings and in the ED—Reply. JAMA, 331 (24), E1-E1. doi: 10.1001/jama.2024.8447
Schlapbach, Luregn J., Ganesamoorthy, Devika, Wilson, Clare, Raman, Sainath, George, Shane, Snelling, Peter J., Phillips, Natalie, Irwin, Adam, Sharp, Natalie, Le Marsney, Renate, Chavan, Arjun, Hempenstall, Allison, Bialasiewicz, Seweryn, MacDonald, Anna D., Grimwood, Keith, Cling, Jessica C., McPherson, Stephen J., Blumenthal, Antje, Kaforou, Myrsini, Levin, Michael, Herberg, Jethro A., Gibbons, Kristen S., Coin, Lachlan J. M., EUCLIDS consortium and RAPIDS Study Group (2024). Host gene expression signatures to identify infection type and organ dysfunction in children evaluated for sepsis: a multicentre cohort study. The Lancet Child and Adolescent Health, 8 (5), 325-338. doi: 10.1016/S2352-4642(24)00017-8
Yeoh, Sophya, Estrada-Rivadeneyra, Diego, Jackson, Heather, Keren, Ilana, Galassini, Rachel, Cooray, Samantha, Shah, Priyen, Agyeman, Philipp, Basmaci, Romain, Carrol, Enitan, Emonts, Marieke, Fink, Colin, Kuijpers, Taco, Martinon-Torres, Federico, Mommert-Tripon, Marine, Paulus, Stephane, Pokorn, Marko, Rojo, Pablo, Romani, Lorenza, Schlapbach, Luregn, Schweintzger, Nina, Shen, Ching-Fen, Tsolia, Maria, Usuf, Effua, van der Flier, Michiel, Vermont, Clementien, von Both, Ulrich, Yeung, Shunmay, Zavadska, Dace ... DIAMONDS and UK KD Genetic Consortia (2024). Plasma protein biomarkers distinguish multisystem inflammatory syndrome in children from other pediatric infectious and inflammatory diseases. Pediatric Infectious Disease Journal, 43 (5), 444-53. doi: 10.1097/inf.0000000000004267
Schöbi, Nina, Sanchez, Carlos, Welzel, Tatjana, Bamford, Alasdair, Webb, Kate, Rojo, Pablo, Tremoulet, Adriana, Atkinson, Andrew, Schlapbach, Luregn J. and Bielicki, Julia Anna (2024). Swissped-RECOVERY: masked independent adjudication for the interpretation of non-randomised treatment in a two-arm open-label randomised controlled trial (methylprednisolone vs immunoglobulins) in Paediatric Inflammatory Multisystem Syndrome Temporally Associated with SARS-CoV-2 (PIMS-TS) involving 10 secondary and tertiary paediatric hospitals in Switzerland. BMJ Open, 14 (4) e078137, 1-8. doi: 10.1136/bmjopen-2023-078137
Khan, Nemat, Kumar, Vinod, Li, Pengcheng, RAPIDS Study Group, Raman, Sainath (RSG member), Sharp, Natalie (RSG member), Irwin, Adam (RSG member), Phillips, Natalie (RSG member), George, Shane (RSG member), Grimwood, Keith (RSG member), Snelling, Peter (RSG member), Chavan, Arjun (RSG member), Hempenstall, Allison (RSG member), Gibbons, Kristen (RSG member), Le Marsney, Renate (RSG member), Blumenthal, Antje (RSG member), Ganesamoorthy, Devika (RSG member), Coin, Lachlan (RSG member), Schlapbach, Luregn J., Boyd, Andrew W., Coulthard, Mark G. and Woodruff, Trent M. (2024). Inhibiting Eph/ephrin signaling reduces vascular leak and endothelial cell dysfunction in mice with sepsis. Science Translational Medicine, 16 (744) eadg5768, 1-15. doi: 10.1126/scitranslmed.adg5768
Aramburo, Angela, Raman, Sainath, Silversides, Jonathan A., Schlapbach, Luregn J., Gibbons, Kristen S., Ramnarayan, Padmanabhan, on behalf of the Australian, New Zealand Intensive Care Society Paediatric Study Group (ANZICS PSG), the United Kingdom Paediatric Critical Care Society Study Group (PCCS-SG), Pellegrini, Breanna, George, Shane, Balit, Corrine, Oberender, Felix, Erickson, Simon, Flores, Jenipher Chumbes, Charles, Karina, Waak, Michaela, Long, Debbie, Butt, Warwick, Delzoppo, Carmel, Gelbart, Ben, Masterson, Kate, Millar, Johnny, Ganeshalingam, Anusha, Sherring, Claire, Singh, Puneet, Smith, Vicky, Schults, Jessica, Darvas, Jennifer and Festa, Marino (2024). Fluid management and active fluid removal practices: a global survey of paediatric critical care physicians. Intensive Care Medicine – Paediatric and Neonatal, 2 (1) 16, 1-16. doi: 10.1007/s44253-024-00038-1
Mozun, Rebeca and Schlapbach, Luregn J. (2024). A Critique of the “Conservative Versus Liberal Oxygenation Targets in Critically Ill Children” Multicenter, Randomized Clinical Trial Published in the Lancet 2024—More on “Less Is More?”. Pediatric Critical Care Medicine, 25 (7), e338-e342. doi: 10.1097/pcc.0000000000003519
Chai, Ming G., Tu, Quyen, Cotta, Menino O., Bauer, Michelle J., Balch, Ross, Okafor, Charles, Comans, Tracy, Kruger, Peter, Meyer, Jason, Shekar, Kiran, Brady, Kara, Fourie, Cheryl, Sharp, Natalie, Vlad, Luminita, Whiley, David, Ungerer, Jacobus P. J., Mcwhinney, Brett C., Farkas, Andras, Paterson, David L., Clark, Julia E., Hajkowicz, Krispin, Raman, Sainath, Bialasiewicz, Seweryn, Lipman, Jeffrey, Forde, Brian M., Harris, Patrick N. A., Schlapbach, Luregn J., Coin, Lachlan, Roberts, Jason A. and Irwin, Adam D. (2024). Correction: achievement of therapeutic antibiotic exposures using Bayesian dosing software in critically unwell children and adults with sepsis. Intensive Care Medicine, 50 (5), 810-810. doi: 10.1007/s00134-024-07393-9
van Loon, Kim, Koomen, Erik, Hiensch, Senna, van Belle- van Haaren, Nicole J. C. W., Koelhuis-Faber, Mizja, Charlier, Jean-Luc, Lammers, Jan, Imhof, Oscar, Nijman, Joppe, van Wijk, Abraham, Breur, Johannes M. P. J., Gibbons, Kristen, Butt, Warwick, Schlapbach, Luregn J., Horton, Stephen, Korporaal, Suzanne and the NITRIC Study Group (2024). Platelet reactivity in young children undergoing congenital heart disease surgery: a NITRIC randomized clinical trial substudy. Intensive Care Medicine – Paediatric and Neonatal, 2 (1) 13. doi: 10.1007/s44253-024-00037-2
Kolberg, Laura, Khanijau, Aakash, van der Velden, Fabian J S, Herberg, Jethro, De, Tisham, Galassini, Rachel, Cunnington, Aubrey J, Wright, Victoria, Shah, Priyen, Kaforou, Myrsini, Wilson, Clare, Kuijpers, Taco, Martinón-Torres, Federico, Rivero-Calle, Irene, Moll, Henriette, Vermont, Clementien, Pokorn, Marko, Kolnik, Mojca, Pollard, Andrew J, Agyeman, Philipp K A, Schlapbach, Luregn J, Tsolia, Maria N, Yeung, Shunmay, Zavadska, Dace, Zenz, Werner, Schweintzger, Nina A, van der Flier, Michiel, de Groot, Ronald, Usuf, Effua ... The PERFORM Consortium (2024). Raising AWaRe-ness of antimicrobial stewardship challenges in pediatric emergency care: results from the PERFORM study assessing consistency and appropriateness of antibiotic prescribing across Europe. Clinical Infectious Diseases, 78 (3), 526-534. doi: 10.1093/cid/ciad615
Chai, Gene G., Tu, Quyen, Cotta, Menino O., Bauer, Michelle J., Balch, Ross, Okafor, Charles, Comans, Tracy, Kruger, Peter, Meyer, Jason, Shekar, Kiran, Brady, Kara, Fourie, Cheryl, Sharp, Natalie, Vlad, Luminita, Whiley, David, Ungerer, Jacobus P. J., McWhinney, Brett C., Farkas, Andras, Paterson, David L., Clark, Julia E., Hajkowicz, Krispin, Raman, Sainath, Bialasiewicz, Seweryn, Lipman, Jeffrey, Forde, Brian M., Harris, Patrick N. A., Schlapbach, Luregn J., Coin, Lachlan, Roberts, Jason A. and Irwin, Adam D. (2024). Achievement of therapeutic antibiotic exposures using Bayesian dosing software in critically unwell children and adults with sepsis. Intensive Care Medicine, 50 (4), 539-547. doi: 10.1007/s00134-024-07353-3
Brossier, David W., Goyer, Isabelle, Verbruggen, Sascha C. A. T., Jotterand Chaparro, Corinne, Rooze, Shancy, Marino, Luise V., Schlapbach, Luregn J., Tume, Lyvonne N. and Valla, Frederic V. (2024). Intravenous maintenance fluid therapy in acutely and critically ill children: state of the evidence. The Lancet Child and Adolescent Health, 8 (3), 236-244. doi: 10.1016/s2352-4642(23)00288-2
Schlapbach, Luregn J., Watson, R. Scott, Sorce, Lauren R., Argent, Andrew C., Menon, Kusum, Hall, Mark W., Akech, Samuel, Albers, David J., Alpern, Elizabeth R., Balamuth, Fran, Bembea, Melania, Biban, Paolo, Carrol, Enitan D., Chiotos, Kathleen, Chisti, Mohammod Jobayer, Dewitt, Peter E., Evans, Idris, Flauzino De Oliveira, Cláudio, Horvat, Christopher M., Inwald, David, Ishimine, Paul, Jaramillo-Bustamante, Juan Camilo, Levin, Michael, Lodha, Rakesh, Martin, Blake, Nadel, Simon, Nakagawa, Satoshi, Peters, Mark J., Randolph, Adrienne G. ... Bennett, Tellen D. (2024). International consensus criteria for pediatric sepsis and septic shock. JAMA, 331 (8), 665-674. doi: 10.1001/jama.2024.0179
Schlapbach, Luregn J., Raman, Sainath, Buckley, David, George, Shane, King, Megan, Ridolfi, Roberta, Harley, Amanda, Cree, Michele, Long, Debbie, Erickson, Simon, Singh, Puneet, Festa, Marino, Gibbons, Kristen, Bellomo, Rinaldo and on behalf of Resuscitation in Paediatric Sepsis Randomized Controlled Pilot Platform in the Paediatric Intensive Care Unit (RESPOND PICU) Study Investigators and the Australian and New Zealand Intensive Care Society Paediatric Study Group (2024). Resuscitation with vitamin C, hydrocortisone, and thiamin in children with septic shock: a multicenter randomized pilot study. Pediatric Critical Care Medicine, 25 (2), 159-170. doi: 10.1097/PCC.0000000000003346
Harley, Amanda, George, Shane, Phillips, Natalie, King, Megan, Long, Debbie, Keijzers, Gerben, Lister, Paula, Raman, Sainath, Bellomo, Rinaldo, Gibbons, Kristen, Schlapbach, Luregn J. and on behalf of Resuscitation in Paediatric Sepsis Randomized Controlled Pilot Platform Study in the Emergency Department (RESPOND ED) Study Group (2024). Resuscitation with early adrenaline infusion for children with septic shock: a randomized pilot trial. Pediatric Critical Care Medicine, 25 (2), 106-117. doi: 10.1097/PCC.0000000000003351
McWhinney, Brett, Ungerer, Jacobus, LeMarsey, Renate, Phillips, Natalie, Raman, Sainath, Gibbons, Kristen, Schlapbach, Luregn J., on behalf of Rapid Acute Paediatric Infection Diagnosis in Suspected Sepsis (RAPIDS) Study Investigators, Irwin, Adam (RAPIDS member) and Bialasiewicz, Seweryn (RAPIDS member) (2024). Serum levels of vitamin C and thiamin in children with suspected sepsis: a prospective observational cohort study. Pediatric Critical Care Medicine, 25 (2), 171-176. doi: 10.1097/PCC.0000000000003349
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Ranjit, Suchitra, Kissoon, Niranjan, Argent, Andrew, Inwald, David, Ventura, Andréa Maria Cordeiro, Jaborinsky, Roberto, Sankar, Jhuma, Carla de Souza, Daniela, Natraj, Rajeswari, Flauzino De Oliveira, Claudio, Samransamruajkit, Rujipat, Jayashree, Muralidharan and Schlapbach, Luregn J (2023). Avoid re-interpreting fluid bolus recommendations for low-income settings – Authors’ reply. The Lancet Child and Adolescent Health, 7 (11), e19-E19. doi: 10.1016/S2352-4642(23)00258-4
Raman, Sainath, Rahiman, Sarfaraz, Kennedy, Melanie, Mattke, Adrian, Venugopal, Prem, McBride, Craig, Tu, Quyen, Zapf, Florian, Kuhlwein, Eva, Woodgate, Jemma, Singh, Puneet, Schlapbach, Luregn J. and Gibbons, Kristen S. (2023). REstrictive versus StandarD FlUid Management in Mechanically Ventilated ChildrEn Admitted to PICU: study protocol for a pilot randomised controlled trial (REDUCE-1). BMJ Open, 13 (11) e076460, 1-8. doi: 10.1136/bmjopen-2023-076460
Wösten-van Asperen, Roelie M., la Roi-Teeuw, Hannah M., van Amstel, Rombout BE., Bos, Lieuwe DJ., Tissing, Wim JE., Jordan, Iolanda, Dohna-Schwake, Christian, Bottari, Gabriella, Pappachan, John, Crazzolara, Roman, Comoretto, Rosanna I., Mizia-Malarz, Agniezka, Moscatelli, Andrea, Sánchez-Martín, María, Willems, Jef, Rogerson, Colin M., Bennett, Tellen D., Luo, Yuan, Atreya, Mihir R., Faustino, E.Vincent S., Geva, Alon, Weiss, Scott L., Schlapbach, Luregn J., Sanchez-Pinto, L Nelson, Caballero, Marina, Margarit, Adriana, Campos, Roi, Möller, Paula, Serpe, Carmela ... Stroup, Emily (2023). Distinct clinical phenotypes in paediatric cancer patients with sepsis are associated with different outcomes—an international multicentre retrospective study. eClinicalMedicine, 65 102252, 102252. doi: 10.1016/j.eclinm.2023.102252
Jackson, Heather R., Zandstra, Judith, Menikou, Stephanie, Hamilton, Melissa Shea, McArdle, Andrew J., Fischer, Roman, Thorne, Adam M., Huang, Honglei, Tanck, Michael W., Jansen, Machiel H., De, Tisham, Agyeman, Philipp K A, Von Both, Ulrich, Carrol, Enitan D., Emonts, Marieke, Eleftheriou, Irini, Van der Flier, Michiel, Fink, Colin, Gloerich, Jolein, De Groot, Ronald, Moll, Henriette A., Pokorn, Marko, Pollard, Andrew J., Schlapbach, Luregn J. (PERFORM consortium), Tsolia, Maria N., Usuf, Effua, Wright, Victoria J., Yeung, Shunmay, Zavadska, Dace ... Kaforou, Myrsini (2023). A multi-platform approach to identify a blood-based host protein signature for distinguishing between bacterial and viral infections in febrile children (PERFORM): a multi-cohort machine learning study. The Lancet. Digital health, 5 (11), e774-e785. doi: 10.1016/S2589-7500(23)00149-8
Jimenez-Zambrano, Andrea, Ritger, Carly, Rebull, Margaret, Wiens, Matthew O., Kabajaasi, Olive, Jaramillo-Bustamante, Juan Camilo, Argent, Andrew C., Kissoon, Niranjan, Schlapbach, Luregn J., Sorce, Lauren R., Watson, R Scott, Dorsey Holliman, Brooke, Sanchez-Pinto, Lazaro N. and Bennett, Tellen D. (2023). Clinical decision support tools for paediatric sepsis in resource-poor settings: an international qualitative study. BMJ open, 13 (10) e074458, 1-9. doi: 10.1136/bmjopen-2023-074458
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Gilholm, Patricia, Ergetu, Endrias, Gelbart, Ben, Raman, Sainath, Festa, Marino, Schlapbach, Luregn J., Long, Debbie, Gibbons, Kristen S. and on behalf of the Australian and New Zealand Intensive Care Society Paediatric Study Group (2023). Adaptive clinical trials in pediatric critical care: a systematic review. Pediatric Critical Care Medicine, 24 (9), 738-749. doi: 10.1097/pcc.0000000000003273
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Schlapbach, Luregn J., Gibbons, Kristen S., Butt, Warwick, Kannankeril, Prince J., Li, Jennifer S., Hill, Kevin D. and for the Nitric Oxide During Cardiopulmonary Bypass to Improve Recovery in Infants With Congenital Heart Defects Follow-Up (NITRIC) Study Group and the Steroids to Reduce Systemic Inflammation after Infant Heart Surgery (STRESS) Network Investigators (2023). Improving outcomes for infants after cardiopulmonary bypass surgery for congenital heart disease: a commentary on recent randomized controlled trials. Pediatric Critical Care Medicine, 24 (11), 961-965. doi: 10.1097/pcc.0000000000003344
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Clark, John A., Conway Morris, Andrew, Kanaris, Constantinos, Inwald, David, Butt, Warwick, Osowicki, Joshua, Schlapbach, Luregn J., Curran, Martin D., White, Deborah, Daubney, Esther, Agrawal, Shruti, Navapurkar, Vilas, Török, M. Estée, Baker, Stephen and Pathan, Nazima (2023). A qualitative investigation of paediatric intensive care staff attitudes towards the diagnosis of lower respiratory tract infection in the molecular diagnostics era. Intensive Care Medicine – Paediatric and Neonatal, 1 (1) 10, 1-12. doi: 10.1007/s44253-023-00008-z
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Cook, Aislinn, Atkinson, Andrew, Kronenberg, Andreas, Agyeman, Philipp K. A., Schlapbach, Luregn J., Berger, Christoph, Bielicki, Julia Anna and Swiss Pediatric Sepsis Study Group (2023). Estimating antibiotic coverage from linked microbiological and clinical data from the Swiss Paediatric Sepsis Study to support empiric antibiotic regimen selection. Frontiers in Pediatrics, 11 1124165, 1-10. doi: 10.3389/fped.2023.1124165
Minogue, Jessicah, Keogh, Samantha, Schlapbach, Luregn J. and Long, Debbie (2023). Long-term outcomes after paediatric sepsis: A narrative review. Australian Critical Care, 37 (3), 499-507. doi: 10.1016/j.aucc.2023.04.002
Carrol, Enitan D., Ranjit, Suchitra, Menon, Kusum, Bennett, Tellen D., Sanchez-Pinto, L. Nelson, Zimmerman, Jerry J., Souza, Daniela C., Sorce, Lauren R., Randolph, Adrienne G., Ishimine, Paul, Flauzino de Oliveira, Claudio, Lodha, Rakesh, Harmon, Lori, Watson, R. Scott, Schlapbach, Luregn J., Kissoon, Niranjan, Argent, Andrew C. and on behalf of the Society of Critical Care Medicine’s Pediatric Sepsis Definition Taskforce (2023). Operationalizing appropriate sepsis definitions in children worldwide: considerations for the pediatric sepsis definition taskforce. Pediatric Critical Care Medicine, 24 (6), e263-e271. doi: 10.1097/pcc.0000000000003263
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Schlapbach, Luregn J., Zimmermann, Elisa A., Meylan, Sylvain, Stocker, Martin, Suter, Peter M., Jakob, Stephan M. and Swiss Sepsis National Action Plan Working Group (2023). Swiss Sepsis National Action Plan: a coordinated national action plan to stop sepsis-related preventable deaths and to improve the support of people affected by sepsis in Switzerland. Frontiers in Medicine, 10 1114546, 1-15. doi: 10.3389/fmed.2023.1114546
Welzel, Tatjana, Atkinson, Andrew, Schöbi, Nina, Andre, Maya C, Bailey, Douggl G N, Blanchard-Rohner, Geraldine, Buettcher, Michael, Grazioli, Serge, Koehler, Henrik, Perez, Marie-Helene, Trück, Johannes, Vanoni, Federica, Zimmermann, Petra, Sanchez, Carlos, Bielicki, Julia A, Schlapbach, Luregn J, Bieri, Andreas, Gysi, Spyridoula, Janz, Indra, Donner, Birgit, Hammer, Jürg, Heininger, Ulrich, Kohns Vasconcelos, Malte, Mettauer, Nicole, Meyer, Alexandra, Reppucci, Diana, Schlaeppi, Chloé, Trachsel, Daniel, Vaezipour, Nina ... Faust, Saul N (2023). Methylprednisolone versus intravenous immunoglobulins in children with paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS): an open-label, multicentre, randomised trial. The Lancet Child & Adolescent Health, 7 (4), 238-248. doi: 10.1016/s2352-4642(23)00020-2
Boeddha, Navin P., Atkins, Lucy, de Groot, Ronald, Driessen, Gertjan, Hazelzet, Jan, Zenz, Werner, Carrol, Enitan D., Anderson, Suzanne T., Martinon-Torres, Federico, Agyeman, Philipp K A, Galassini, Rachel, Herberg, Jethro, Levin, Michael, Schlapbach, Luregn J. and Emonts, Marieke (2023). Erratum: Correction to: Group A streptococcal disease in paediatric inpatients: a European perspective (European journal of pediatrics (2023) 182 2 (697-706)). European journal of pediatrics, 182 (2), 707-707. doi: 10.1007/s00431-022-04787-z
van der Velden, Fabian J. S., de Vries, Gabriella, Martin, Alexander, Lim, Emma, von Both, Ulrich, Kolberg, Laura, Carrol, Enitan D., Khanijau, Aakash, Herberg, Jethro A., De, Tisham, Galassini, Rachel, Kuijpers, Taco W., Martinón-Torres, Federico, Rivero-Calle, Irene, Vermont, Clementien L., Hagedoorn, Nienke N., Pokorn, Marko, Pollard, Andrew J., Schlapbach, Luregn J., Tsolia, Maria, Elefhteriou, Irini, Yeung, Shunmay, Zavadska, Dace, Fink, Colin, Voice, Marie, Zenz, Werner, Kohlmaier, Benno, Agyeman, Philipp K. A., Usuf, Effua ... PERFORM consortium (2023). Correction to: Febrile illness in high-risk children: a prospective, international observational study. European Journal of Pediatrics, 182 (2), 555-556. doi: 10.1007/s00431-022-04788-y
Bialasiewicz, Seweryn, May, Meryta, Tozer, Sarah, Day, Rebecca, Bernard, Anne, Zaugg, Julian, Gartrell, Kyana, Alexandersen, Soren, Chamings, Anthony, Wang, Claire Y. T., Clark, Julia, Grimwood, Keith, Heney, Claire, Schlapbach, Luregn, Ware, Robert S., Speers, David, Andrews, Ross M. and Lambert, Stephen (2023). HPeV3 diversity, recombination and clinical impact across 7-years: an Australian story. The Journal of Infectious Diseases, 227 (2), 278-287. doi: 10.1093/infdis/jiac311
Gilholm, Patricia, Gibbons, Kristen, Lister, Paula, Harley, Amanda, Irwin, Adam, Raman, Sainath, Rice, Michael, Schlapbach, Luregn J. and Queensland Statewide Sepsis Collaborative (2023). Validation of a paediatric sepsis screening tool to identify children with sepsis in the emergency department: a statewide prospective cohort study in Queensland, Australia. BMJ Open, 13 (1) e061431, 1-25. doi: 10.1136/bmjopen-2022-061431
Giamarellos-Bourboulis, Evangelos J., Zinkernagel, Annelies S., De Robertis, Edoardo, Azoulay, Élie, De Luca, Daniele, Artigas, Antonio, Schlapbach, Luregn J, Daniels, Ron, Reinhart, Konrad, Reinhart, Konrad, Baño, Jesús Rodríguez, Zacharowski, Kai and Cecconi, Maurizio (2023). Sepsis, a call for inclusion in the work plan of the European Center for Disease Prevention and Control. Intensive Care Medicine, 49 (9), 1138-1142. doi: 10.1007/s00134-023-07127-3
Giamarellos-Bourboulis, Evangelos J., Zinkernagel, Annelies S., De Robertis, Edoardo, Azoulay, Élie, De Luca, Daniele, Artigas, Antonio, Schlapbach, Luregn J, Daniels, Ron, Reinhart, Konrad, Baño, Jesús Rodríguez, Zacharowski, Kai and Cecconi, Maurizio (2023). Correction: Sepsis, a call for inclusion in the work plan of the European Center for Disease Prevention and Control (Intensive Care Medicine, (2023), 10.1007/s00134-023-07127-3). Intensive Care Medicine, 49 (10), 1280-1280. doi: 10.1007/s00134-023-07197-3
Tan, Chantal D., Vermont, Clementien L., Zachariasse, Joany M., von Both, Ulrich, Eleftheriou, Irini, Emonts, Marieke, van der Flier, Michiel, Herberg, Jethro, Kohlmaier, Benno, Levin, Michael, Lim, Emma, Maconochie, Ian K., Martinon-Torres, Federico, Nijman, Ruud G., Pokorn, Marko, Rivero-Calle, Irene, Tsolia, Maria, Zenz, Werner, Zavadska, Dace, Moll, Henriëtte A., Carrol, Enitan D., Levin, Michael, Cunnington, Aubrey, De, Tisham, Herberg, Jethro, Kaforou, Myrsini, Wright, Victoria, Baumard, Lucas, Bellos, Evangelos ... On behalf of PERFORM consortium (Personalised Risk assessment in febrile children to optimize Real-life Management across the European Union) (2023). Emergency medical services utilisation among febrile children attending emergency departments across Europe: an observational multicentre study. European Journal of Pediatrics, 182 (9), 3939-3947. doi: 10.1007/s00431-023-05056-3
Raman, Sainath, Gibbons, Kristen S., Mattke, Adrian, Schibler, Andreas, Trnka, Peter, Kennedy, Melanie, Le Marsney, Renate and Schlapbach, Luregn J. (2022). Effect of Saline vs gluconate/acetate–buffered solution vs lactate-buffered solution on serum chloride among children in the pediatric Intensive Care Unit: the SPLYT-P randomized clinical trial. JAMA Pediatrics, 177 (2), 122-131. doi: 10.1001/jamapediatrics.2022.4912
Boeddha, Navin P., Schlapbach, Luregn J., Visser, Idse H., Jansen, Nicolaas J. G., Bollen, Casper, van Heerde, Marc, van der Heide, Douwe, Klein, Richard, Kneyber, Martin, Kuiper, Jan-Willem, Riedijk, Maaike, Verlaat, Carin and van Waardenburg, Dick (2022). Validation of an adapted Pediatric Sepsis Score in children admitted to PICU with invasive infection and sepsis: a retrospective analysis of a Dutch national cohort. Journal of Intensive Care, 10 (1) 26, 26. doi: 10.1186/s40560-022-00618-3
Hagedoorn, Nienke N., Boeddha, Navin P., Kohlfuerst, Daniela S., Anderson, Suzanne, Carrol, Enitan D., Agapow, Paul, Van Der Flier, Michiel, Hazelzet, Jan, Herberg, Jethro, Kuijpers, Taco, Levin, Michael, Martinon-Torres, Federico, Van Rijswijk, Angelique, Schlapbach, Luregn J., Vermont, Clementien, Zenz, Werner, Dik, Willem A., Driessen, Gertjan and Emonts, Marieke (2022). Hemostasis proteins in invasive meningococcal and nonmeningococcal infections: a prospective multicenter study. Pediatric Critical Care Medicine, 23 (12), E543-E554. doi: 10.1097/PCC.0000000000003056
Nielsen, Jeppe S. A., Agbeko, Rachel, Bate, Jessica, Jordan, Iolanda, Dohna-Schwake, Christian, Potratz, Jenny, Moscatelli, Andrea, Bottari, Gabriella, Pappachan, John, Witt, Volker, Crazzolara, Roman, Amigoni, Angela, Mizia-Malarz, Agniezka, Sánchez Martín, Mariá, Willems, Jef, van den Heuvel-Eibrink, Marry M., Schlapbach, Luregn J., Wösten-van Asperen, Roelie M. and the POKER (PICU Oncology Kids in Europe Research group) research consortium of ESPNIC (European Society of Paediatric & Neonatal Intensive Care) (2022). Organizational characteristics of European pediatric onco-critical care: An international cross-sectional survey. Frontiers in Pediatrics, 10 1024273, 1-10. doi: 10.3389/fped.2022.1024273
Boeddha, Navin P., Atkins, Lucy, de Groot, Ronald, Driessen, Gertjan, Hazelzet, Jan, Zenz, Werner, Carrol, Enitan D., Anderson, Suzanne T., Martinon-Torres, Federico, Agyeman, Philipp K. A., Galassini, Rachel, Herberg, Jethro, Levin, Michael, Schlapbach, Luregn J. and Emonts, Marieke (2022). Group A streptococcal disease in paediatric inpatients: a European perspective. European Journal of Pediatrics, 182 (2), 697-706. doi: 10.1007/s00431-022-04718-y
Brossier, David W., Tume, Lyvonne N., Briant, Anais R., Jotterand Chaparro, Corinne, Moullet, Clemence, Rooze, Shancy, Verbruggen, Sascha C. A. T., Marino, Luise V., Alsohime, Fahad, Beldjilali, Sophie, Chiusolo, Fabrizio, Costa, Leonardo, Didier, Capucine, Ilia, Stavroula, Joram, Nyandat L., Kneyber, Martin C. J., Kuhlwein, Eva, Lopez, Jorge, Lopez-Herce, Jesus, Mayberry, Huw F., Mehmeti, Fortesa, Mierzewska-Schmidt, Magdalena, Minambres Rodriguez, Maria, Morice, Claire, Pappachan, John V., Porcheret, Florence, Reis Boto, Leonor, Schlapbach, Luregn J., Tekguc, Hakan ... Valla, Frederic V. (2022). Correction: ESPNIC clinical practice guidelines: intravenous maintenance fluid therapy in acute and critically ill children-a systematic review and meta-analysis. Intensive Care Medicine, 49 (1), 128-129. doi: 10.1007/s00134-022-06933-5
Schlapbach, Luregn J. and Carrol, Enitan D. (2022). Reducing antibiotic exposure at the beginning of life. JAMA Network Open, 5 (11) e2243705, 1-3. doi: 10.1001/jamanetworkopen.2022.43705
Schlapbach, Luregn J and Peters, Mark J (2022). Pragmatic trials for critical illness in neonates and children. The Lancet Child & Adolescent Health, 7 (2), 78-79. doi: 10.1016/s2352-4642(22)00345-5
Pinto, Neethi P., Maddux, Aline B., Dervan, Leslie A., Woodruff, Alan G., Jarvis, Jessica M., Nett, Sholeen, Killien, Elizabeth Y., Graham, Robert J., Choong, Karen, Luckett, Peter M., Heneghan, Julia A., Biagas, Katherine, Carlton, Erin F., Hartman, Mary E., Yagiela, Lauren, Michelson, Kelly N., Manning, Joseph C., Long, Debbie A., Lee, Jan Hau, Slomine, Beth S., Beers, Sue R., Hall, Trevor, Morrow, Brenda M., Meert, Kathleen, Arias Lopez, Maria Del Pilar, Knoester, Hennie, Houtrow, Amy, Olson, Lenora, Steele, Lisa ... Zuppa, Athena (2022). A core outcome measurement set for pediatric critical care. Pediatric Critical Care Medicine, 23 (11), 893-907. doi: 10.1097/PCC.0000000000003055
Brossier, David W., Tume, Lyvonne N., Briant, Anais R., Jotterand Chaparro, Corinne, Moullet, Clémence, Rooze, Shancy, Verbruggen, Sascha C. A. T., Marino, Luise V., Alsohime, Fahad, Beldjilali, Sophie, Chiusolo, Fabrizio, Costa, Leonardo, Didier, Capucine, Ilia, Stavroula, Joram, Nyandat L., Kneyber, Martin C. J., Kühlwein, Eva, Lopez, Jorge, López-Herce, Jesus, Mayberry, Huw F., Mehmeti, Fortesa, Mierzewska-Schmidt, Magdalena, Miñambres Rodríguez, Maria, Morice, Claire, Pappachan, John V., Porcheret, Florence, Reis Boto, Leonor, Schlapbach, Luregn J., Tekguc, Hakan ... the Metabolism Endocrinology and Nutrition section of the European Society of Pediatric and Neonatal Intensive Care (ESPNIC) (2022). ESPNIC clinical practice guidelines: intravenous maintenance fluid therapy in acute and critically ill children— a systematic review and meta-analysis. Intensive Care Medicine, 48 (12), 1691-1708. doi: 10.1007/s00134-022-06882-z
van der Velden, Fabian J. S., de Vries, Gabriella, Martin, Alexander, Lim, Emma, von Both, Ulrich, Kolberg, Laura, Carrol, Enitan D., Khanijau, Aakash, Herberg, Jethro A., De, Tisham, Galassini, Rachel, Kuijpers, Taco W., Martinón-Torres, Federico, Rivero-Calle, Irene, Vermont, Clementien L., Hagedoorn, Nienke N., Pokorn, Marko, Pollard, Andrew J., Schlapbach, Luregn J., Tsolia, Maria, Elefhteriou, Irini, Yeung, Shunmay, Zavadska, Dace, Fink, Colin, Voice, Marie, Zenz, Werner, Kohlmaier, Benno, Agyeman, Philipp K. A., Usuf, Effua ... Emonts, Marieke (2022). Febrile illness in high-risk children: a prospective, international observational study. European Journal of Pediatrics, 182 (2), 543-554. doi: 10.1007/s00431-022-04642-1
Tan, Chantal D., van der Walle, Eline E. P. L., Vermont, Clementien L., von Both, Ulrich, Carrol, Enitan D., Eleftheriou, Irini, Emonts, Marieke, van der Flier, Michiel, de Groot, Ronald, Herberg, Jethro, Kohlmaier, Benno, Levin, Michael, Lim, Emma, Maconochie, Ian K., Martinon-Torres, Federico, Nijman, Ruud G., Pokorn, Marko, Rivero-Calle, Irene, Tsolia, Maria, Yeung, Shunmay, Zenz, Werner, Zavadska, Dace, Moll, Henriëtte A., Levin, Michael, Cunnington, Aubrey, De, Tisham, Herberg, Jethro, Kaforou, Myrsini, Wright, Victoria ... Geissler, J. (2022). Guideline adherence in febrile children below 3 months visiting European Emergency Departments: an observational multicenter study. European Journal of Pediatrics, 181 (12), 4199-4209. doi: 10.1007/s00431-022-04606-5
Kumar, Vikrant, Pouw, Richard B., Autio, Matias I., Sagmeister, Manfred G., Phua, Zai Yang, Borghini, Lisa, Wright, Victoria J., Hoggart, Clive, Pan, Bangfen, Tan, Antson Kiat Yee, Binder, Alexander, Brouwer, Mieke C., Pinnock, Ellie, De Groot, Ronald, Hazelzet, Jan, Emonts, Marieke, Van Der Flier, Michiel, Reiter, Karl, Nöthen, Markus M., Hoffmann, Per, Schlapbach, Luregn J., Bellos, Evangelos, Anderson, Suzanne, Secka, Fatou, Martinón-Torres, Federico, Salas, Antonio, Fink, Colin, Carrol, Enitan D., Pollard, Andrew J. ... Davila, Sonia (2022). Variation in CFHR3 determines susceptibility to meningococcal disease by controlling factor H concentrations. American Journal of Human Genetics, 109 (9), 1680-1691. doi: 10.1016/j.ajhg.2022.08.001
Morice, Claire, Alsohime, Fahad, Mayberry, Huw, Tume, Lyvonne N., Brossier, David, Valla, Frederic V., Didier, Capucine, Moullet, Clémence, Jotterand Chaparro, Corinne, Kühlwein, Eva, Chiusolo, Fabrizio, Porcheret, Florence, Mehmeti, Fortesa, Tekguc, Hakan, Ilia, Stavroula, Goyer, Isabelle, Lopez-Herce, Jesus, Pappachan, John, Lopez, Jorge, Tziouvas, Konstantinos, Costa, Leonardo, Boto, Leonor Reis, Marino, Luise, Schlapbach, Luregn J, Mierzewska-Schmidt, Magdalena, Minambres, Maria, Kneyber, Martin, Fae, Monica, Joram, Nyandat ... Beldjilali, Sophie (2022). Correction to: Intravenous maintenance fluid therapy practice in the pediatric acute and critical care settings: a European and Middle Eastern survey (European Journal of Pediatrics, (2022), 181, 8, (3163-3172), 10.1007/s00431-022-04467-y). European Journal of Pediatrics, 181 (8), 3173-3173. doi: 10.1007/s00431-022-04513-9
Clos, Maité, Schlapbach, Luregn J., Arata-Bardet, Julie, Javouhey, Etienne and Mortamet, Guillaume (2022). Antimicrobial stewardship programs in European pediatric intensive care units: an international survey of practices. European Journal of Pediatrics, 181 (7), 2873-2877. doi: 10.1007/s00431-022-04481-0
Long, Debbie, Gibbons, Kristen, Dow, Belinda, Best, James, Webb, Kerri-Lyn, Liley, Helen G., Stocker, Christian, Thoms, Debra, Schlapbach, Luregn J., Wharton, Carolyn, Lister, Paula, Matuschka, Lori, Castillo, Maria Isabel, Tyack, Zephanie and Bora, Samudragupta (2022). Effectiveness–implementation hybrid-2 randomised trial of a collaborative Shared Care Model for Detecting Neurodevelopmental Impairments after Critical Illness in Young Children (DAISY): pilot study protocol. BMJ Open, 12 (7) e060714, 1-11. doi: 10.1136/bmjopen-2021-060714
Fan, Bowen, Klatt, Juliane, Moor, Michael M., Daniels, Latasha A., Sanchez-Pinto, Lazaro N., Agyeman, Philipp K. A., Schlapbach, Luregn J. and Borgwardt, Karsten M. (2022). Prediction of recovery from multiple organ dysfunction syndrome in pediatric sepsis patients. Bioinformatics, 38 (Supplement 1), I101-I108. doi: 10.1093/bioinformatics/btac229
Schlapbach, Luregn J. and Kissoon, Niranjan (2022). Resuscitating children with sepsis and impaired perfusion with maintenance fluids: an evolving concept. Pediatric Critical Care Medicine, 23 (7), 563-565. doi: 10.1097/PCC.0000000000002990
Schlapbach, Luregn J., Gibbons, Kristen S., Horton, Stephen B., Johnson, Kerry, Long, Debbie A., Buckley, David H. F., Erickson, Simon, Festa, Marino, D'Udekem, Yves, Alphonso, Nelson, Winlaw, David S., Delzoppo, Carmel, Van Loon, Kim, Jones, Mark, Young, Paul J., Butt, Warwick and Schibler, Andreas (2022). Effect of nitric oxide via cardiopulmonary bypass on ventilator-free days in young children undergoing congenital heart disease surgery: the NITRIC Randomized Clinical Trial. JAMA: Journal of the American Medical Association, 328 (1), 38-47. doi: 10.1001/jama.2022.9376
Blythe, Robin, Lister, Paula, Seaton, Robert, Harley, Amanda, Schlapbach, Luregn J., McPhail, Steven, Venkatesh, Bala, Irwin, Adam, Raman, Sainath, Schlapbach, Luregn, Harley, Amanda, Irwin, Adam, Graham, Nicolette, Thomson, Fiona, Owen, Kieran, Garrish, Kirsten, Sampson, Emma, Long, Debbie, George, Shane, Grimwood, Keith, Bell, Christa, Semple, Bethany, Adams, Claire, Brown, Josea, Maloney, Louise, Lister, Paula, Schofield, Scott, Thomas, Clare, Dejong, Liam ... the Queensland State-wide Sepsis Collaborative (2022). Patient and economic impact of implementing a paediatric sepsis pathway in emergency departments in Queensland, Australia. Scientific Reports, 12 (1) 10113, 10113. doi: 10.1038/s41598-022-14226-6
Morin, Luc, Hall, Mark, de Souza, Daniela, Guoping, Lu, Jabornisky, Roberto, Shime, Nobuaki, Ranjit, Suchitra, Gilholm, Patricia, Nakagawa, Satoshi, Zimmerman, Jerry J., Sorce, Lauren R., Argent, Andrew, Kissoon, Niranjan, Tissières, Pierre, Watson, R. Scott and Schlapbach, Luregn J (2022). The current and future state of pediatric sepsis definitions: an international survey. Pediatrics, 149 (6) e2021052565. doi: 10.1542/peds.2021-052565
Welzel, Tatjana, Schöbi, Nina, André, Maya C., Bailey, Douggl G. N., Blanchard-Rohner, Geraldine, Buettcher, Michael, Grazioli, Serge, Koehler, Henrik, Perez, Marie-Helene, Trück, Johannes, Vanoni, Federica, Zimmermann, Petra, Atkinson, Andrew, Sanchez, Carlos, Whittaker, Elizabeth, Faust, Saul N., Bielicki, Julia A. and Schlapbach, Luregn J. (2022). Multicenter randomized trial of methylprednisolone vs. intravenous immunoglobulins to treat the pediatric inflammatory multisystem syndrome—temporally associated with SARS-CoV-2 (PIMS-TS): protocol of the Swissped RECOVERY Trial. Frontiers in Pediatrics, 10 905046, 1-12. doi: 10.3389/fped.2022.905046
Schlapbach, Luregn J, Hagmann, Cornelia and Giannoni, Eric (2022). Time to tackle early-onset sepsis in low-income and middle-income countries. The Lancet Global Health, 10 (5), e592-e593. doi: 10.1016/S2214-109X(22)00086-9
Equey, Lucile, Agyeman, Philipp K. A., Veraguth, Rosemarie, Rezzi, Serge, Schlapbach, Luregn J. and Giannoni, Eric (2022). Serum ascorbic acid and thiamine concentrations in sepsis: secondary analysis of the Swiss Pediatric Sepsis Study. Pediatric Critical Care Medicine, 23 (5), 390-394. doi: 10.1097/PCC.0000000000002911
Fernández-Sarmiento, Jaime, Schlapbach, Luregn J., Acevedo, Lorena, Santana, Carolina Ramírez, Acosta, Yeny, Diana, Ampudia, Monsalve, M. and Carcillo, Joseph A. (2022). Endothelial damage in sepsis: the importance of systems biology. Frontiers in Pediatrics, 10 828968, 828968. doi: 10.3389/fped.2022.828968
Stocker, Martin, Daunhawer, Imant, Van Herk, Wendy, El Helou, Salhab, Dutta, Sourabh, Schuerman, Frank A. B. A., Van Den Tooren-De Groot, Rita K., Wieringa, Jantien W., Janota, Jan, Van Der Meer-Kappelle, Laura H., Moonen, Rob, Sie, Sintha D., De Vries, Esther, Donker, Albertine E., Zimmerman, Urs, Schlapbach, Luregn J., De Mol, Amerik C., Hoffmann-Haringsma, Angelique, Roy, Madan, Tomaske, Maren, Kornelisse, René F., Van Gijsel, Juliette, Plötz, Frans B., Wellmann, Sven, Achten, Niek B., Lehnick, Dirk, Van Rossum, Annemarie M. C. and Vogt, Julia E. (2022). Machine learning used to compare the diagnostic accuracy of risk factors, clinical signs and biomarkers and to develop a new prediction model for neonatal early-onset sepsis. Pediatric Infectious Disease Journal, 41 (3), 248-254. doi: 10.1097/INF.0000000000003344
Tomaszewski, Wojtek, Ablaza, Christine, Straney, Lahn, Taylor, Catherine, Millar, Johnny, Schlapbach, Luregn and on behalf of the Australian & New Zealand Intensive Care Society (ANZICS) Centre for Outcomes & Resource Evaluation (CORE) and the Australian & New Zealand Intensive Care Society Paediatric Study Group (ANZICS PSG) (2022). Educational outcomes of childhood survivors of critical illness—A population-based linkage study. Critical Care Medicine, 50 (6), 901-912. doi: 10.1097/CCM.0000000000005461
McBride, Craig Antony, Rahiman, Sarfaraz, Schlapbach, Luregn J., Schults, Jessica A., Kleidon, Tricia M., Kennedy, Melanie, Paterson, Rebecca S., Byrnes, Joshua, Ware, Robert S. and Ullman, Amanda Judith (2022). Comparing ivWatch biosensor to standard care to identify extravasation injuries in the paediatric intensive care: a protocol for a randomised controlled trial. BMJ Open, 12 (2) e047765, e047765. doi: 10.1136/bmjopen-2020-047765
Schlapbach, Luregn J and Coin, Lachlan (2022). Understanding detrimental host response to infection: the promise of transcriptomics. Pediatric critical care medicine, 23 (2), 133-135. doi: 10.1097/PCC.0000000000002870
Menon, Kusum, Schlapbach, Luregn J., Akech, Samuel, Argent, Andrew, Biban, Paolo, Carrol, Enitan D., Chiotos, Kathleen, Chisti, Mohammod Jobayer, Evans, Idris V. R., Inwald, David P., Ishimine, Paul, Kissoon, Niranjan, Lodha, Rakesh, Nadel, Simon, Oliveira, Cláudio Flauzino, Peters, Mark, Sadeghirad, Benham, Scott, Halden F., De Souza, Daniela C., Tissieres, Pierre, Watson, R. Scott, Wiens, Matthew O., Wynn, James L., Zimmerman, Jerry J. and Sorce, Lauren R. (2022). Criteria for pediatric sepsis - a systematic review and meta-analysis by the pediatric sepsis definition taskforce. Critical Care Medicine, 50 (1), 21-36. doi: 10.1097/CCM.0000000000005294
Slooff, Valerie, Hoogendoorn, Rianne, Nielsen, Jeppe Sylvest Angaard, Pappachan, John, Amigoni, Angela, Caramelli, Fabio, Aziz, Omer, Wildschut, Enno, Verbruggen, Sascha, Crazzolara, Roman, Dohna-Schwake, Christian, Potratz, Jenny, Willems, Jef, Llevadias, Judit, Moscatelli, Andrea, Montaguti, Alessia, Bottari, Gabriella, Di Nardo, Matteo, Schlapbach, Luregn, Wösten-van Asperen, Roelie and POKER (PICU Oncology Kids in Europe Research group) research consortium of ESPNIC (European Society of Paediatric Neonatal Intensive Care) (2022). Role of extracorporeal membrane oxygenation in pediatric cancer patients: a systematic review and meta-analysis of observational studies. Annals of Intensive Care, 12 (1) 8, 1-11. doi: 10.1186/s13613-022-00983-0
Doo, Irene, Staub, Lukas P., Mattke, Adrian, Haisz, Emma, Seidler, Anna Lene, Alphonso, Nelson and Schlapbach, Luregn J. (2022). Diagnostic accuracy of infection markers to diagnose infections in neonates and children receiving extracorporeal membrane oxygenation. Frontiers in Pediatrics, 9 824552, 824552. doi: 10.3389/fped.2021.824552
Henry, Cían J., Semova, Gergana, Barnes, Ellen, Cotter, Isabel, Devers, Tara, Rafaee, Aisyah, Slavescu, Andreea, Cathain, Niamh O., McCollum, Danielle, Roche, Edna, Mockler, David, Allen, John, Meehan, Judith, Klingenberg, Claus, Latour, Jos M., van den Hoogen, Agnes, Strunk, Tobias, Giannoni, Eric, Schlapbach, Luregn J., Degtyareva, Marina, Plötz, Frans B., de Boode, Willem P., Naver, Lars, Wynn, James L., Küster, Helmut, Janota, Jan, Keij, Fleur M., Reiss, Irwin K. M., Bliss, Joseph M. ... Molloy, Eleanor J. (2022). Neonatal sepsis: a systematic review of core outcomes from randomised clinical trials. Pediatric Research, 91 (4), 735-742. doi: 10.1038/s41390-021-01883-y
Schlapbach, Luregn J., Weiss, Scott L., Bembea, Melania M., Carcillo, Joseph A., Leclerc, Francis, Leteurtre, Stephane, Tissieres, Pierre, Wynn, James L., Zimmerman, Jerry and Lacroix, Jacques (2022). Scoring systems for organ dysfunction and multiple organ dysfunction: the PODIUM Consensus Conference. Pediatrics, 149 (Supplement 1) e2021052888D, S23-S31. doi: 10.1542/peds.2021-052888D
Weiss, Scott L., Carcillo, Joseph A., Leclerc, Francis, Leteurtre, Stephane, Schlapbach, Luregn J., Tissieres, Pierre, Wynn, James L. and Lacroix, Jacques (2022). Refining the pediatric multiple organ dysfunction syndrome. Pediatrics, 149 (1) e2021052888C, S13-S22. doi: 10.1542/peds.2021-052888C
Bembea, Melania M., Agus, Michael, Akcan-Arikan, Ayse, Alexander, Peta, Basu, Rajit, Bennett, Tellen D., Bohn, Desmond, Brandão, Leonardo R., Brown, Ann-Marie, Carcillo, Joseph A., Checchia, Paul, Cholette, Jill, Cheifetz, Ira M., Cornell, Timothy, Doctor, Allan, Eckerle, Michelle, Erickson, Simon, Farris, Reid W D, Faustino, E Vincent S, Fitzgerald, Julie C., Fuhrman, Dana Y., Giuliano, John S., Guilliams, Kristin, Gaies, Michael, Gorga, Stephen M., Hall, Mark, Hanson, Sheila J., Hartman, Mary, Hassinger, Amanda B. ... Zimmerman, Jerry J. (2022). Pediatric Organ Dysfunction Information Update Mandate (PODIUM) contemporary organ dysfunction criteria: executive summary. Pediatrics, 149 (1) e2021052888B, S1-S12. doi: 10.1542/peds.2021-052888B
Geraerds, A. J.L.M., van Herk, Wendy, Stocker, Martin, el Helou, Salhab, Dutta, Sourabh, Fontana, Matteo S., Schuerman, Frank A. B. A., van den Tooren-de Groot, Rita K., Wieringa, Jantien, Janota, Jan, van der Meer-Kappelle, Laura H., Moonen, Rob, Sie, Sintha D., de Vries, Esther, Donker, Albertine E., Zimmerman, Urs, Schlapbach, Luregn J., de Mol, Amerik C., Hoffman-Haringsma, Angelique, Roy, Madan, Tomaske, Maren, Kornelisse, René F., van Gijsel, Juliette, Visser, Eline G., van Rossum, Annemarie M. C. and Polinder, Suzanne (2021). Cost impact of procalcitonin-guided decision making on duration of antibiotic therapy for suspected early-onset sepsis in neonates. Critical Care, 25 (1) 367, 367. doi: 10.1186/s13054-021-03789-x
Schlapbach, Luregn J., van Rossum, Annemarie and Carrol, Enitan D. (2021). Antibiotics for neonatal sepsis in low-income and middle-income countries—where to go from here?. The Lancet Infectious Diseases, 21 (12), 1617-1618. doi: 10.1016/S1473-3099(21)00199-7
Hayes, Rían, Hartnett, Jack, Semova, Gergana, Murray, Cian, Murphy, Katherine, Carroll, Leah, Plapp, Helena, Hession, Louise, O’Toole, Jonathan, McCollum, Danielle, Roche, Edna, Jenkins, Elinor, Mockler, David, Hurley, Tim, McGovern, Matthew, Allen, John, Meehan, Judith, Plötz, Frans B., Strunk, Tobias, de Boode, Willem P., Polin, Richard, Wynn, James L., Degtyareva, Marina, Küster, Helmut, Janota, Jan, Giannoni, Eric, Schlapbach, Luregn J., Keij, Fleur M., Reiss, Irwin K. M. ... Molloy, Eleanor J. (2021). Neonatal sepsis definitions from randomised clinical trials. Pediatric Research, 93 (5), 1-8. doi: 10.1038/s41390-021-01749-3
Venkatesh, Balasubramanian, Schlapbach, Luregn, Mason, Donna, Wilks, Kathryn, Seaton, Robert, Lister, Paula, Irwin, Adam, Lane, Paul, Redpath, Lyndell, Gibbons, Kristen, Ergetu, Endrias and Rice, Michael (2021). Impact of 1-hour and 3-hour sepsis time bundles on patient outcomes and antimicrobial use: a before and after cohort study. The Lancet Regional Health - Western Pacific, 18 100305, 100305. doi: 10.1016/j.lanwpc.2021.100305
Harley, Amanda, Lister, Paula, Gilholm, Patricia, Rice, Michael, Venkatesh, Bala, Johnston, Amy N.B., Massey, Debbie, Irwin, Adam, Gibbons, Kristen and Schlapbach, Luregn J. (2021). Queensland Pediatric Sepsis Breakthrough Collaborative: Multicenter Observational Study to Evaluate the Implementation of a Pediatric Sepsis Pathway Within the Emergency Department. Critical Care Explorations, 3 (11) e0573, 1-14. doi: 10.1097/cce.0000000000000573
Boeddha, Navin P., Driessen, Gertjan J., Hagedoorn, Nienke N., Kohlfuerst, Daniela S., Hoggart, Clive J., van Rijswijk, Angelique L., Ekinci, Ebru, Priem, Debby, Schlapbach, Luregn J., Herberg, Jethro A., de Groot, Ronald, Anderson, Suzanne T., Fink, Colin G., Carrol, Enitan D., van der Flier, Michiel, Martinón-Torres, Federico, Levin, Michael, Leebeek, Frank W., Zenz, Werner, de Maat, Moniek P. M., Hazelzet, Jan A., Emonts, Marieke and Dik, Willem A. (2021). Detectable A Disintegrin and Metalloproteinase with Thrombospondin Motifs-1 in serum is associated with adverse outcome in pediatric sepsis. Critical Care Explorations, 3 (11) e0569, e0569. doi: 10.1097/CCE.0000000000000569
Harley, Amanda, Schlapbach, Luregn J., Lister, Paula, Massey, Debbie, Gilholm, Patricia and Johnston, Amy N. B. (2021). Knowledge translation following the implementation of a state-wide Paediatric Sepsis Pathway in the emergency department- a multi-centre survey study. BMC Health Services Research, 21 (1) 1161, 1161. doi: 10.1186/s12913-021-07128-2
Simpson, Adam, Long, Deborah, Fleischmann-Struzek, Carolin, Minogue, Jessicah, Venkatesh, Balasubramanian, Hammond, Naomi E., Tian, David H. and Schlapbach, Luregn J. (2021). Long-term functional outcomes after sepsis for adult and pediatric critical care patients—protocol for a systematic review. Frontiers in Pediatrics, 9 734205, 734205. doi: 10.3389/fped.2021.734205
Schlapbach, Luregn J., de Oliveira, Claudio Flauzinho, Raman, Sainath and de Souza, Daniela (2021). Metabolic resuscitation in pediatric sepsis: a narrative review. Translational Pediatrics, 10 (10), 2678-2688. doi: 10.21037/tp-21-1
Schlapbach, Luregn J., Reinhart, Konrad, Kissoon, Niranjan and On behalf of the Pediatric Sepsis Data CoLaboratory (Sepsis CoLab) and the Global Sepsis Alliance (GSA) (2021). A pediatric perspective on World Sepsis Day in 2021: leveraging lessons from the pandemic to reduce the global pediatric sepsis burden?. American Journal of Physiology-Lung Cellular and Molecular Physiology, 321 (3), L608-L613. doi: 10.1152/ajplung.00331.2021
Sever, Zoe, Schlapbach, Luregn J, Jessup, Melanie, George, Shane and Harley, Amanda (2021). Parental and healthcare professional concern in the diagnosis of paediatric sepsis: a protocol for a prospective multicentre observational study. BMJ Open, 11 (9) e045910, e045910. doi: 10.1136/bmjopen-2020-045910
Nijman, Ruud G., Oostenbrink, Rianne, Moll, Henriette A., Casals-Pascual, Climent, von Both, Ulrich, Cunnington, Aubrey, De, Tisham, Eleftheriou, Irini, Emonts, Marieke, Fink, Colin, van der Flier, Michiel, de Groot, Ronald, Kaforou, Myrsini, Kohlmaier, Benno, Kuijpers, Taco W., Lim, Emma, Maconochie, Ian K., Paulus, Stephane, Martinon-Torres, Federico, Pokorn, Marko, Romaine, Sam T., Calle, Irene Rivero, Schlapbach, Luregn J., Smit, Frank J., Tsolia, Maria, Usuf, Effua, Wright, Victoria J., Yeung, Shunmay, Zavadska, Dace ... Carrol, Enitan D. (2021). A novel framework for phenotyping children with suspected or confirmed infection for future biomarker studies. Frontiers in Pediatrics, 9 688272, 1-18. doi: 10.3389/fped.2021.688272
Tu, Quyen, Cotta, Menino, Raman, Sainath, Graham, Nicolette, Schlapbach, Luregn and Roberts, Jason A (2021). Individualized precision dosing approaches to optimize antimicrobial therapy in pediatric populations. Expert Review of Clinical Pharmacology, 14 (11), 1-17. doi: 10.1080/17512433.2021.1961578
Raman, Sainath, Schibler, Andreas, Le Marsney, Renate, Trnka, Peter, Kennedy, Melanie, Mattke, Adrian, Gibbons, Kristen and Schlapbach, Luregn J. (2021). 0.9% Sodium chloride solution versus Plasma-Lyte 148 versus compound sodium lacTate solution in children admitted to PICU—a randomized controlled trial (SPLYT-P): study protocol for an intravenous fluid therapy trial. Trials, 22 (1) 427. doi: 10.1186/s13063-021-05376-5
McArdle, Andrew J., Vito, Ortensia, Patel, Harsita, Seaby, Eleanor G., Shah, Priyen, Wilson, Clare, Broderick, Claire, Nijman, Ruud, Tremoulet, Adriana H., Munblit, Daniel, Ulloa-Gutierrez, Rolando, Carter, Michael J., De, Tisham, Hoggart, Clive, Whittaker, Elizabeth, Herberg, Jethro A., Kaforou, Myrsini, Cunnington, Aubrey J., Levin, Michael, Vazquez, Jorge Agrimbau, Carmona, Rodrigo, Perez, Laura, Rubinos, Mayra, Veliz, Natalia, Yori, Silvana, Haerynck, Filomeen, Hoste, Levi, Leal, Izabel Alves, Da Silva, Andre Ricardo Araujo ... Kandawasvika, Gwendoline (2021). Treatment of Multisystem Inflammatory Syndrome in Children. New England Journal of Medicine, 385 (1) NEJMoa2102968, 11-22. doi: 10.1056/NEJMoa2102968
Irwin, Adam D., Coin, Lachlan J. M., Harris, Patrick N. A., Cotta, Menino Osbert, Bauer, Michelle J., Buckley, Cameron, Balch, Ross, Kruger, Peter, Meyer, Jason, Shekar, Kiran, Brady, Kara, Fourie, Cheryl, Sharp, Natalie, Vlad, Luminita, Whiley, David, Beatson, Scott A., Forde, Brian M., Paterson, David, Clark, Julia, Hajkowicz, Krispin, Raman, Sainath, Bialasiewicz, Seweryn, Lipman, Jeffrey, Schlapbach, Luregn J. and Roberts, Jason A. (2021). Optimising treatment outcomes for children and adults through rapid genome sequencing of sepsis pathogens. A study protocol for a prospective, multi-centre trial (DIRECT). Frontiers in Cellular and Infection Microbiology, 11 667680, 1-8. doi: 10.3389/fcimb.2021.667680
Raman, Sainath, Brown, Georgia, Long, Debbie, Gelbart, Ben, Delzoppo, Carmel, Millar, Johnny, Erickson, Simon, Festa, Marino, Schlapbach, Luregn J., For the Australian and New Zealand Intensive Care Society Paediatric Study Group (ANZICS PSG) and Gibbons, Kristen (2021). Priorities for paediatric critical care research: a modified Delphi study by the Australian and New Zealand Intensive Care Society Paediatric Study Group. Critical Care and Resuscitation, 23 (2), 194-201. doi: 10.51893/2021.2.oa6
Harley, Amanda, George, Shane, King, Megan, Phillips, Natalie, Keijzers, Gerben, Long, Debbie, Gibbons, Kristen, Bellomo, Rinaldo and Schlapbach, Luregn J. (2021). Early resuscitation in paediatric sepsis using inotropes – a randomised controlled pilot study in the emergency department (RESPOND ED): study protocol and analysis plan. Frontiers in Pediatrics, 9 663028, 663028. doi: 10.3389/fped.2021.663028
Schlapbach, Luregn J., Andre, Maya C., Grazioli, Serge, Schöbi, Nina, Ritz, Nicole, Aebi, Christoph, Agyeman, Philipp, Albisetti, Manuela, Bailey, Douggl G. N., Berger, Christoph, Blanchard-Rohner, Géraldine, Bressieux-Degueldre, Sabrina, Hofer, Michael, L'Huillier, Arnaud G., Marston, Mark, Meyer Sauteur, Patrick M., Pachlopnik Schmid, Jana, Perez, Marie-Helene, Rogdo, Bjarte, Trück, Johannes, Woerner, Andreas, Wütz, Daniela, Zimmermann, Petra, Levin, Michael, Whittaker, Elizabeth and Rimensberger, Peter C. (2021). Best practice recommendations for the diagnosis and management of children with pediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS; multisystem inflammatory syndrome in children, MIS-C) in Switzerland. Frontiers in Pediatrics, 9 667507, 667507. doi: 10.3389/fped.2021.667507
Romaine, Sam T., Sefton, Gerri, Lim, Emma, Nijman, Ruud G., Bernatoniene, Jolanta, Clark, Simon, Schlapbach, Luregn J., Pallmann, Philip and Carrol, Enitan D. (2021). Performance of seven different paediatric early warning scores to predict critical care admission in febrile children presenting to the emergency department: a retrospective cohort study. BMJ Open, 11 (5) e044091, e044091. doi: 10.1136/bmjopen-2020-044091
Schlapbach, Luregn J., Gibbons, Kristen, Ridolfi, Roberta, Harley, Amanda, Cree, Michele, Long, Debbie, Buckley, David, Erickson, Simon, Festa, Marino, George, Shane, King, Megan, Singh, Puneet, Raman, Sainath, Bellomo, Rinaldo and The RESPOND PICU study investigators and the Australian New Zealand Intensive Care Society Paediatric Study Group (ANZICS PSG) (2021). Resuscitation in Paediatric Sepsis Using Metabolic Resuscitation–A Randomized Controlled Pilot Study in the Paediatric Intensive Care Unit (RESPOND PICU): Study Protocol and Analysis Plan. Frontiers in Pediatrics, 9 663435, 1-10. doi: 10.3389/fped.2021.663435
Harley, Amanda, Schlapbach, Luregn J., Johnston, Amy N. B. and Massey, Debbie (2021). Challenges in the recognition and management of paediatric sepsis — the journey. Australasian Emergency Care, 25 (1), 23-29. doi: 10.1016/j.auec.2021.03.006
Long, Elliot, Schlapbach, Luregn J. and Babl, Franz E. (2021). The challenge of infrequency. Acta Paediatrica, 110 (3), 1075-1075. doi: 10.1111/apa.15647
Datta, Rachit, Di Tanna, Gian Luca, Youssef, Marina, Harley, Amanda, Schlapbach, Luregn J., Nunnink, Leo and Venkatesh, Balasubramanian (2021). An assessment of knowledge and education about sepsis among medical students: a multi-university survey. Critical Care and Resuscitation, 23 (1), 117-118. doi: 10.51893/2021.1.rl2
Gibbons, Kristen S., Schlapbach, Luregn J., Horton, Stephen B., Long, Debbie A., Beca, John, Erickson, Simon, Festa, Marino, d'Udekem, Yves, Alphonso, Nelson, Winlaw, David, Johnson, Kerry, Delzoppo, Carmel, van Loon, Kim, Gannon, Brenda, Fooken, Jonas, Blumenthal, Antje, Young, Paul J., Butt, Warwick and Schibler, Andreas (2021). Statistical analysis plan for the NITric oxide during cardiopulmonary bypass to improve Recovery in Infants with Congenital heart defects (NITRIC) trial. Critical Care and Resuscitation, 23 (1), 47-58.
Gibbons, Kristen S., Schlapbach, Luregn J., Johnson, Kerry, Horton, Stephen B., Long, Debbie A., Beca, John, Erickson, Simon, Festa, Marino, d’Udekem, Yves, Alphonso, Nelson, Winlaw, David, Delzoppo, Carmel, van Loon, Kim, Gannon, Brenda, Fooken, Jonas, Blumenthal, Antje, Young, Paul J., Butt, Warwick and Schibler, Andreas (2021). Statistical analysis plan for the NITric oxide during cardiopulmonary bypass to improve Recovery in Infants with Congenital heart defects (NITRIC) trial. Critical Care and Resuscitation, 23 (1), 47-58. doi: 10.51893/2021.1.oa4
Yanase, Fumitaka, Raman, Sainath, Naorungroj, Thummaporn, McCarthy, Avril, Cree, Michele, Schlapbach, Luregn J and Bellomo, Rinaldo (2021). Efficacy and safety of parenteral high-dose vitamin C therapy in pediatric patients: a scoping review. Pediatric critical care medicine: a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 22 (6), 561-571. doi: 10.1097/PCC.0000000000002686
Born, Sebastian, Dame, Christof, Matthäus-Krämer, Claudia, Schlapbach, Luregn J., Reichert, Felix, Schettler, Anna, Schwarzkopf, Daniel, Thomas-Rüddel, Daniel, Proquitté, Hans, Reinhart, Konrad and Fleischmann-Struzek, Carolin (2021). Epidemiology of sepsis among children and neonates in Germany: Results from an observational study based on nationwide diagnosis-related groups data between 2010 and 2016∗. Critical Care Medicine, 49 (7), 1049-1057. doi: 10.1097/CCM.0000000000004919
Harley, Amanda, Massey, Debbie, Ullman, Amanda J., Reid-Searl, Kerry, Schlapbach, Luregn J., Takashima, Mari, Venkatesh, Bala, Datta, Rachit and Johnston, Amy N.B. (2021). Final year nursing student's exposure to education and knowledge about sepsis: a multi-university study. Nurse Education Today, 97 104703, 104703. doi: 10.1016/j.nedt.2020.104703
Rimensberger, Peter C., Kneyber, Martin C. J., Deep, Akash, Bansal, Mehak, Hoskote, Aparna, Javouhey, Etienne, Jourdain, Gilles, Latten, Lynne, MacLaren, Graeme, Morin, Luc, Pons-Odena, Marti, Ricci, Zaccaria, Singh, Yogen, Schlapbach, Luregn J., Scholefield, Barnaby R., Terheggen, Ulrich, Tissières, Pierre, Tume, Lyvonne N., Verbruggen, Sascha, Brierley, Joe and European Society of Pediatric and Neonatal Intensive Care (ESPNIC) Scientific Sections’ Collaborative Group (2021). Caring for Critically Ill Children With Suspected or Proven Coronavirus Disease 2019 Infection: Recommendations by the Scientific Sections' Collaborative of the European Society of Pediatric and Neonatal Intensive Care. Pediatric Critical Care Medicine, 22 (1), 56-67. doi: 10.1097/PCC.0000000000002599
Tai, Chian Wern, Gibbons, Kristen, Schibler, Andreas, Schlapbach, Luregn J. and Raman, Sainath (2021). Acute kidney injury: epidemiology and course in critically ill children. Journal of Nephrology, 35 (2), 559-565. doi: 10.1007/s40620-021-01071-5
Reinhart, K., Levy, M. M., Finfer, Simon S., Machado, F., Kaplan, L., Kesecioglu, J., Rhodes, A., Daniels, R., Kissoon, N., Nsutebu, E., Gorordo, L. A., Malik, I., Alhawsawi, A., Cecconi, M., Giamarellos, E., Martin, G., Schlapbach, L. and The European Society of Intensive Care Medicine (ESICM), (2021). Reducing the global burden of sepsis: a positive legacy for the COVID-19 pandemic?. Intensive Care Medicine, 47 (7), 733-736. doi: 10.1007/s00134-021-06409-y
Romaine, Sam T., Potter, Jessica, Khanijau, Aakash, McGalliard, Rachel J., Wright, Jemma L., Sefton, Gerri, Leigh, Simon, Edwardson, Karl, Johnston, Philip, Kerr, Anne, Schlapbach, Luregn J., Pallmann, Philip and Carrol, Enitan D. (2020). Accuracy of a modified qSOFA score for predicting critical care admission in febrile children. Pediatrics, 146 (4) e20200782, e20200638. doi: 10.1542/peds.2020-0782
Ramanathan, Kollengode, Yeo, Nicholas, Alexander, Peta, Raman, Lakshmi, Barbaro, Ryan, Tan, Chuen Seng, Schlapbach, Luregn J. and MacLaren, Graeme (2020). Role of extracorporeal membrane oxygenation in children with sepsis: a systematic review and meta-analysis. Critical Care, 24 (1) 684, 684. doi: 10.1186/s13054-020-03418-z
Giannoni, Eric and Schlapbach, Luregn J. (2020). Editorial: Sepsis in Neonates and Children. Frontiers in Pediatrics, 8 621663, 621663. doi: 10.3389/fped.2020.621663
Lunke, Sebastian, Eggers, Stefanie, Wilson, Meredith, Patel, Chirag, Barnett, Christopher P., Pinner, Jason, Sandaradura, Sarah A., Buckley, Michael F., Krzesinski, Emma I., de Silva, Michelle G., Brett, Gemma R., Boggs, Kirsten, Mowat, David, Kirk, Edwin P., Adès, Lesley C., Akesson, Lauren S., Amor, David J., Ayres, Samantha, Baxendale, Anne, Borrie, Sarah, Bray, Alessandra, Brown, Natasha J., Chan, Cheng Yee, Chong, Belinda, Cliffe, Corrina, Delatycki, Martin B., Edwards, Matthew, Elakis, George, Fahey, Michael C. ... Stark, Zornitza (2020). Feasibility of ultra-rapid exome sequencing in critically ill infants and children with suspected monogenic conditions in the australian public health care system. Obstetrical and Gynecological Survey, 75 (11), 662-664. doi: 10.1097/01.ogx.0000722040.32795.04
Weiss, Scott L., Peters, Mark J., Agus, Michael S. D., Alhazzani, Waleed, Choong, Karen, Flori, Heidi R., Inwald, David P., Nadel, Simon, Nunnally, Mark E., Schlapbach, Luregn J., Tasker, Robert C., Tissieres, Pierre and Kissoon, Niranjan (2020). Perspective of the Surviving Sepsis Campaign on the Management of Pediatric Sepsis in the era of coronavirus disease 2019∗. Pediatric Critical Care Medicine, 21 (11), E1031-E1037. doi: 10.1097/PCC.0000000000002553
Molloy, Eleanor J., Wynn, James L., Bliss, Joseph, Koenig, Joyce M., Keij, Fleur M., McGovern, Matt, Kuester, Helmut, Turner, Mark A., Giannoni, Eric, Mazela, Jan, Degtyareva, Marina, Strunk, Tobias, Simons, Sinno H. P., Janota, Jan, Plotz, Franz B., van den Hoogen, Ages, de Boode, Willem, Schlapbach, Luregn J., Reiss, Irwin K. M. and Infection, Inflammation, Immunology and Immunisation (I4) section of the ESPR (2020). Correction: Neonatal sepsis: need for consensus definition, collaboration and core outcomes. Pediatric Research, 90 (1), 232-232. doi: 10.1038/s41390-020-01221-8
Sanchez-Pinto, L Nelson, González-Dambrauskas, Sebastián, Jabornisky, Roberto, Naidoo, Kuban, Schlapbach, Luregn J and Kissoon, Niranjan (2020). Sepsis hysteria? Not for children. The Lancet, 396 (10259), 1332-1333. doi: 10.1016/S0140-6736(20)32148-6
Schlapbach, Luregn J. and Watson, R. Scott (2020). Adapting Pediatric Sepsis Criteria for Benchmarking and Quality Control - The Search for the Holy Grail Continues. Critical Care Medicine, 48 (10), 1549-1551. doi: 10.1097/CCM.0000000000004535
Cruz, Andrea T., Lane, Roni D., Balamuth, Fran, Aronson, Paul L., Ashby, David W., Neuman, Mark I., Souganidis, Ellie S., Alpern, Elizabeth R. and Schlapbach, Luregn J. (2020). Updates on pediatric sepsis. Journal of the American College of Emergency Physicians open, 1 (5), 981-993. doi: 10.1002/emp2.12173
Long, Elliot, Solan, Tom, Stephens, David J., Schlapbach, Luregn J., Williams, Amanda, Tse, Wai Chung and Babl, Franz E. (2020). Febrile children in the Emergency Department: frequency and predictors of poor outcome. Acta Paediatrica, International Journal of Paediatrics, 110 (3) apa.15602, 1046-1055. doi: 10.1111/apa.15602
Stocker, Martin, van Herk, Wendy, El Helou, Salhab, Dutta, Sourabh, Schuerman, Frank A. B. A., van den Tooren-de Groot, Rita K., Wieringa, Jantien W., Janota, Jan, van der Meer-Kappelle, Laura H., Moonen, Rob, Sie, Sintha D., de Vries, Esther, Donker, Albertine E., Zimmerman, Urs, Schlapbach, Luregn J., de Mol, Amerik C., Hoffman-Haringsma, Angelique, Roy, Madan, Tomaske, Maren, F Kornelisse, René, van Gijsel, Juliette, Visser, Eline G., Plötz, Frans B., Heath, Paul, Achten, Niek B., Lehnick, Dirk and van Rossum, Annemarie M. C. (2020). C-Reactive Protein, Procalcitonin, and White Blood Count to Rule Out Neonatal Early-onset Sepsis Within 36 Hours: A Secondary Analysis of the Neonatal Procalcitonin Intervention Study. Clinical Infectious Diseases, 73 (2), e383-e390. doi: 10.1093/cid/ciaa876
Gc, Vijay S., Franklin, Donna, Whitty, Jennifer A., Dalziel, Stuart R., Babl, Franz E., Schalpbach, Luregn J., Fraser, John F., Craig, Simon, Neutze, Jocelyn, Oakley, Ed and Schibler, Andreas (2020). First-line oxygen therapy with high-flow in bronchiolitis is not cost saving for the health service. Archives of Disease in Childhood, 105 (10), 975-980. doi: 10.1136/archdischild-2019-318427
Schlapbach, Luregn J., Kissoon, Niranjan, Alhawsawi, Abdulelah, Aljuaid, Maha H., Daniels, Ron, Gorordo-Delsol, Luis A., Machado, Flavia, Malik, Imrana, Nsutebu, Emmanuel Fru, Finfer, Simon and Reinhart, Konrad (2020). World Sepsis Day: a global agenda to target a leading cause of morbidity and mortality. American Journal of Physiology-Lung Cellular and Molecular Physiology, 319 (3), L518-L522. doi: 10.1152/ajplung.00369.2020
Raman, Sainath, Tai, Chian Wern, Le Marsney, Renate, Schibler, Andreas, Gibbons, Kristen and Schlapbach, Luregn J. (2020). Prediction of Acute Kidney Injury on Admission to Pediatric Intensive Care. Pediatric Critical Care Medicine, 21 (9), 811-819. doi: 10.1097/pcc.0000000000002411
Balamuth, Fran and Schlapbach, Luregn J. (2020). Paediatric patient stratification in the emergency department. The Lancet Child and Adolescent Health, 4 (8), 557-558. doi: 10.1016/S2352-4642(20)30208-X
Schlapbach, Luregn J., Chatfield, Mark D., Rycus, Peter and MacLaren, Graeme (2020). Extracorporeal membrane oxygenation for group B streptococcal sepsis in neonates: a retrospective study of the extracorporeal life support organization registry. Pediatric Critical Care Medicine, 21 (8), e505-e512. doi: 10.1097/PCC.0000000000002320
Namachivayam, Siva P., Carlin, John B., Millar, Johnny, Alexander, Janet, Edmunds, Sarah, Ganeshalingham, Anusha, Lew, Jamie, Erickson, Simon, Butt, Warwick, Schlapbach, Luregn J., Ganu, Subodh, Festa, Marino, Egan, Jonathan R., Williams, Gary and Young, Janelle (2020). Gestational age and risk of mortality in term-born critically ill neonates admitted to PICUs in Australia and New Zealand*. Critical Care Medicine, 48 (8), E648-E656. doi: 10.1097/CCM.0000000000004409
Zandstra, Judith, van de Geer, Annemarie, Tanck, Michael W. T., van Stijn-Bringas Dimitriades, Diana, Aarts, Cathelijn E. M., Dietz, Sanne M., van Bruggen, Robin, Schweintzger, Nina A., Zenz, Werner, Emonts, Marieke, Zavadska, Dace, Pokorn, Marko, Usuf, Effua, Moll, Henriette A., Schlapbach, Luregn J., Carrol, Enitan D., Paulus, Stephane, Tsolia, Maria, Fink, Colin, Yeung, Shunmay, Shimizu, Chisato, Tremoulet, Adriana, Galassini, Rachel, Wright, Victoria J., Martinón-Torres, Federico, Herberg, Jethro, Burns, Jane, Levin, Michael and Kuijpers, Taco W. (2020). Biomarkers for the discrimination of acute Kawasaki disease from infections in childhood. Frontiers in Pediatrics, 8 355, 355. doi: 10.3389/fped.2020.00355
Schlapbach, Luregn J., Trück, Johannes and Roger, Thierry (2020). Editorial: The immunology of sepsis—understanding host susceptibility, pathogenesis of disease, and avenues for future treatment. Frontiers in Immunology, 11 1263, 1263. doi: 10.3389/fimmu.2020.01263
Lunke, Sebastian, Eggers, Stefanie, Wilson, Meredith, Patel, Chirag, Barnett, Christopher P., Pinner, Jason, Sandaradura, Sarah A., Buckley, Michael F., Krzesinski, Emma I., De Silva, Michelle G., Brett, Gemma R., Boggs, Kirsten, Mowat, David, Kirk, Edwin P., Adès, Lesley C., Akesson, Lauren S., Amor, David J., Ayres, Samantha, Baxendale, Anne, Borrie, Sarah, Bray, Alessandra, Brown, Natasha J., Chan, Cheng Yee, Chong, Belinda, Cliffe, Corrina, Delatycki, Martin B., Edwards, Matthew, Elakis, George, Fahey, Michael C. ... Stark, Zornitza (2020). Feasibility of ultra-rapid exome sequencing in critically ill infants and children with suspected monogenic conditions in the Australian public health care system. JAMA - Journal of the American Medical Association, 323 (24), 2503-2511. doi: 10.1001/jama.2020.7671
Babl, Franz E., Franklin, Donna, Schlapbach, Luregn J., Oakley, Ed, Dalziel, Stuart, Whitty, Jennifer A., Neutze, Jocelyn, Furyk, Jeremy, Craig, Simon, Fraser, John F., Jones, Mark and Schibler, Andreas (2020). Enteral hydration in high-flow therapy for infants with bronchiolitis: secondary analysis of a randomised trial. Journal of Paediatrics and Child Health, 56 (6) jpc.14799, 950-955. doi: 10.1111/jpc.14799
Menon, Kusum, Schlapbach, Luregn J., Akech, Samuel, Argent, Andrew, Chiotos, Kathleen, Chisti, Mohammod Jobayer, Hamid, Jemila, Ishimine, Paul, Kissoon, Niranjan, Lodha, Rakesh, Oliveira, Cláudio Flauzino, Peters, Mark, Tissieres, Pierre, Watson, R. Scott, Wiens, Matthew O., Wynn, James L., Sorce, Lauren R. and for the Pediatric Sepsis Definition Taskforce of the Society of Critical Care Medicine (2020). Pediatric Sepsis Definition-A Systematic Review Protocol by the Pediatric Sepsis Definition Taskforce. Critical Care Explorations, 2 (6), e0123. doi: 10.1097/CCE.0000000000000123
Mashbat, Bayarchimeg, Bellos, Evangelos, Hodeib, Stephanie, Bidmos, Fadil, Thwaites, Ryan S., Lu, Yaxuan, Wright, Victoria J., Herberg, Jethro A., Klobassa, Daniela S., Zenz, Werner, Hansel, Trevor T., Nadel, Simon, Langford, Paul R., Schlapbach, Luregn J., Li, Ming-Shi, Redinbo, Matthew R., Di, Y Peter, Levin, Michael and Sancho-Shimizu, Vanessa (2020). A rare mutation in SPLUNC1 affects bacterial adherence and invasion in meningococcal disease. Clinical Infectious Diseases, 70 (10), 2045-2053. doi: 10.1093/cid/ciz600
Molloy, Eleanor J., Wynn, James L., Bliss, Joseph, Koenig, Joyce M., Keij, Fleur M., McGovern, Matt, Kuester, Helmut, Turner, Mark A., Giannoni, Eric, Mazela, Jan, Degtyaeva, Marina, Strunk, Tobias, Simons, Sinno H. P., Janota, Jan, Plotz, Franz B., van den Hoogen, Ages, de Boode, Willem, Schlapbach, Luregn J. and Reiss, Irwin K. M. (2020). Neonatal sepsis: need for consensus definition, collaboration and core outcomes. Pediatric Research, 88 (1), 2-4. doi: 10.1038/s41390-020-0850-5
Borghesi, Alessandro, Trück, Johannes, Asgari, Samira, Sancho-Shimizu, Vanessa, Agyeman, Philipp K. A., Bellos, Evangelos, Giannoni, Eric, Stocker, Martin, Posfay-Barbe, Klara M., Heininger, Ulrich, Bernhard-Stirnemann, Sara, Niederer-Loher, Anita, Kahlert, Christian R., Natalucci, Giancardlo, Relly, Christa, Riedel, Thomas, Kuehni, Claudia E., Thorball, Christian W., Chaturvedi, Nimisha, Martinon-Torres, Federico, Kuijpers, Taco W., Coin, Lachlan, Wright, Victoria, Herberg, Jethro, Levin, Michael, Aebi, Christoph, Berger, Christoph, Fellay, Jacques, Schlapbach, Luregn J. and EUCLIDS consortium and the Swiss Paediatric Sepsis Study (2020). Whole-exome sequencing for the identification of rare variants in primary immunodeficiency genes in children with sepsis - a prospective population-based cohort study. Clinical Infectious Diseases, 71 (10), E614-E623. doi: 10.1093/cid/ciaa290
Moynihan, Katie M., McGarvey, Tambra, Barlow, Andrew, Heney, Claire, Gibbons, Kristen, Clark, Julia E., Schlebusch, Sanmarié and Schlapbach, Luregn J. (2020). Testing for Common Respiratory Viruses in Children Admitted to Pediatric Intensive Care: Epidemiology and Outcomes. Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 21 (6), 1-e341. doi: 10.1097/PCC.0000000000002302
MacLaren, Graeme, Schlapbach, Luregn J. and Aiken, Alexander M. (2020). Nosocomial infections during extracorporeal membrane oxygenation in neonatal, pediatric, and adult patients: a comprehensive narrative review. Pediatric Critical Care Medicine, 21 (3), 283-290. doi: 10.1097/PCC.0000000000002190
Weiss, Scott L., Peters, Mark J., Alhazzani, Waleed, Agus, Michael S D, Flori, Heidi R., Inwald, David P., Nadel, Simon, Schlapbach, Luregn J., Tasker, Robert C., Argent, Andrew C., Brierley, Joe, Carcillo, Joseph, Carrol, Enitan D., Carroll, Christopher L., Cheifetz, Ira M., Choong, Karen, Cies, Jeffry J., Cruz, Andrea T., De Luca, Daniele, Deep, Akash, Faust, Saul N., De Oliveira, Claudio Flauzino, Hall, Mark W., Ishimine, Paul, Javouhey, Etienne, Joosten, Koen F. M., Joshi, Poonam, Karam, Oliver, Kneyber, Martin C. J. ... Tissieres, Pierre (2020). Surviving Sepsis Campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in children. Pediatric Critical Care Medicine, 21 (2), e52-e106. doi: 10.1097/PCC.0000000000002198
Weiss, Scott L., Peters, Mark J., Alhazzani, Waleed, Agus, Michael S D, Flori, Heidi R., Inwald, David P., Nadel, Simon, Schlapbach, Luregn J., Tasker, Robert C., Argent, Andrew C., Brierley, Joe, Carcillo, Joseph, Carrol, Enitan D., Carroll, Christopher L., Cheifetz, Ira M., Choong, Karen, Cies, Jeffry J., Cruz, Andrea T., De Luca, Daniele, Deep, Akash, Faust, Saul N., De Oliveira, Claudio Flauzino, Hall, Mark W., Ishimine, Paul, Javouhey, Etienne, Joosten, Koen F M, Joshi, Poonam, Karam, Oliver, Kneyber, Martin C J ... Tissieres, Pierre (2020). Executive summary: Surviving Sepsis Campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in children. Pediatric Critical Care Medicine, 21 (2), 186-195. doi: 10.1097/PCC.0000000000002197
Weiss, Scott L., Peters, Mark J., Alhazzani, Waleed, Agus, Michael S. D., Flori, Heidi R., Inwald, David P., Nadel, Simon, Schlapbach, Luregn J., Tasker, Robert C., Argent, Andrew C., Brierley, Joe, Carcillo, Joseph, Carrol, Enitan D., Carroll, Christopher L., Cheifetz, Ira M., Choong, Karen, Cies, Jeffry J., Cruz, Andrea T., De Luca, Daniele, Deep, Akash, Faust, Saul N., De Oliveira, Claudio Flauzino, Hall, Mark W., Ishimine, Paul, Javouhey, Etienne, Joosten, Koen F. M., Joshi, Poonam, Karam, Oliver, Kneyber, Martin C. J. ... Tissieres, Pierre (2020). Surviving sepsis campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in children. Intensive Care Medicine, 46 (S1), 10-67. doi: 10.1007/s00134-019-05878-6
Weiss, Scott L., Peters, Mark J., Alhazzani, Waleed, Agus, Michael S D, Flori, Heidi R., Inwald, David P., Nadel, Simon, Schlapbach, Luregn J., Tasker, Robert C., Argent, Andrew C., Brierley, Joe, Carcillo, Joseph, Carrol, Enitan D., Carroll, Christopher L., Cheifetz, Ira M., Choong, Karen, Cies, Jeffry J., Cruz, Andrea T., De Luca, Daniele, Deep, Akash, Faust, Saul N., De Oliveira, Claudio Flauzino, Hall, Mark W., Ishimine, Paul, Javouhey, Etienne, Joosten, Koen F M, Joshi, Poonam, Karam, Oliver, Kneyber, Martin C J ... Tissieres, Pierre (2020). Executive summary: surviving sepsis campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in children. Intensive Care Medicine, 46 (S1), 1-9. doi: 10.1007/s00134-019-05877-7
Obonyo, Nchafatso Gikenyi, Schlapbach, Luregn Jan and Fraser, John Francis (2020). Corrigendum: Sepsis: changing definitions, unchanging treatment (vol 6, 425, 2019). Frontiers in Pediatrics, 7 538, 538. doi: 10.3389/fped.2019.00538
Franklin, Donna, Shellshear, Deborah, Babl, Franz E., Schlapbach, Luregn J., Oakley, Ed, Borland, Meredith L., Hoeppner, Tobias, George, Shane, Craig, Simon, Neutze, Jocelyn, Williams, Amanda, Acworth, Jason, McCay, Hamish, Wallace, Alex, Mattes, Joerg, Gangathimn, Vinay, Wildman, Mark, Fraser, John F, Moloney, Susan, Gavranich, John, Waugh, John, Hobbins, Sue, Fahy, Rose, Grew, Simon, Gannon, Brenda, Gibbons, Kristen, Dalziel, Stuart and Schibler, Andreas (2019). Multicentre, randomised trial to investigate early nasal high—flow therapy in paediatric acute hypoxaemic respiratory failure: a protocol for a randomised controlled trial—a Paediatric Acute respiratory Intervention Study (PARIS 2). BMJ Open, 9 (12) e030516, e030516. doi: 10.1136/bmjopen-2019-030516
Morin, Luc, Kneyber, Martin, Jansen, Nicolaas J. G., Peters, Mark J., Javouhey, Etienne, Nadel, Simon, Maclaren, Graeme, Schlapbach, Luregn Jan and Tissieres, Pierre (2019). Translational gap in pediatric septic shock management: an ESPNIC perspective. Annals of Intensive Care, 9 (1) 73, 73. doi: 10.1186/s13613-019-0545-4
Schlapbach, Luregn J., Chiletti, Roberto, Straney, Lahn, Festa, Marino, Alexander, Daniel, Butt, Warwick and MacLaren, Graeme (2019). Defining benefit threshold for extracorporeal membrane oxygenation in children with sepsis—a binational multicenter cohort study. Critical Care, 23 (1) 429, 429. doi: 10.1186/s13054-019-2685-1
Wang, Xinzhu, Nijman, Ruud, Camuzeaux, Stephane, Sands, Caroline, Jackson, Heather, Kaforou, Myrsini, Emonts, Marieke, Herberg, Jethro A., Maconochie, Ian, Carrol, Enitan D., Paulus, Stephane C., Zenz, Werner, Van der Flier, Michiel, de Groot, Ronald, Martinon-Torres, Federico, Schlapbach, Luregn J., Pollard, Andrew J., Fink, Colin, Kuijpers, Taco T., Anderson, Suzanne, Lewis, Matthew R., Levin, Michael, McClure, Myra and & EUCLIDS consortium (2019). Plasma lipid profiles discriminate bacterial from viral infection in febrile children. Scientific Reports, 9 (1) 17714, 17714. doi: 10.1038/s41598-019-53721-1
Asner, Sandra A., Agyeman, Philipp K. A., Gradoux, Eugénie, Posfay-Barbe, Klara M., Heininger, Ulrich, Giannoni, Eric, Crisinel, Pierre A., Stocker, Martin, Bernhard-Stirnemann, Sara, Niederer-Loher, Anita, Kahlert, Christian R., Hasters, Paul, Relly, Christa, Baer, Walter, Aebi, Christoph, Schlapbach, Luregn J. and Berger, Christoph (2019). Burden of Streptococcus pneumoniae sepsis in children after introduction of pneumococcal conjugate vaccines: a prospective population-based cohort study. Clinical Infectious Diseases, 69 (9), 1574-1580. doi: 10.1093/cid/ciy1139
Schlapbach, Luregn J, Thompson, Kelly and Finfer, Simon R (2019). The WHO resolution on sepsis: what action is needed in Australia?. Medical Journal of Australia, 211 (9), 395-397.e1. doi: 10.5694/mja2.50279
May, M. L. A., Tozer, S., Day, R., Doyle, R., Bernard, A., Schlapbach, L. J., Heney, C., Clark, J. E. and Bialasiewicz, S. (2019). Polymerase chain reaction for human parechovirus on blood samples improves detection of clinical infections in infants. Molecular Biology Reports, 47 (1), 715-720. doi: 10.1007/s11033-019-05151-5
Franklin, Donna, Babl, Franz E., Gibbons, Kristen, Pham, Trang M. T., Hasan, Nadia, Schlapbach, Luregn J., Oakley, Ed, Craig, Simon, Furyk, Jeremy, Neutze, Jocelyn, Moloney, Susan, Gavranich, John, Shirkhedkar, Prasanna, Kapoor, Vishal, Grew, Simon, Fraser, John F., Dalziel, Stuart, Schibler, Andreas and and PARIS and PREDICT (2019). Nasal high flow in room air for hypoxemic bronchiolitis infants. Frontiers in Pediatrics, 7 426, 426. doi: 10.3389/fped.2019.00426
Schlapbach, Luregn J. (2019). Paediatric sepsis. Current Opinion in Infectious Diseases, 32 (5), 497-504. doi: 10.1097/QCO.0000000000000583
Achten, Niek B., Klingenberg, Claus, Benitz, William E., Stocker, Martin, Schlapbach, Luregn J., Giannoni, Eric, Bokelaar, Robin, Driessen, Gertjan J. A., Brodin, Petter, Uthaya, Sabita, Van Rossum, Annemarie M. C. and Plötz, Frans B. (2019). Association of use of the neonatal early-onset sepsis calculator with reduction in antibiotic therapy and safety: A systematic review and meta-analysis. JAMA Pediatrics, 173 (11), 1032-1040. doi: 10.1001/jamapediatrics.2019.2825
Moynihan, Katie M., Alexander, Peta M. A., Schlapbach, Luregn J., Millar, Johnny, Jacobe, Stephen, Ravindranathan, Hari, Croston, Elizabeth J., Staffa, Steven J., Burns, Jeffrey P. and Gelbart, Ben (2019). Epidemiology of childhood death in Australian and New Zealand intensive care units. Intensive Care Medicine, 45 (9), 1262-1271. doi: 10.1007/s00134-019-05675-1
Secka, F., Herberg, J. A., Sarr, I., Darboe, S., Sey, G., Saidykhan, M., Wathuo, M., Kaforou, M., Antonio, M., Roca, A., Zaman, S. M.A., Cebey-López, M., Boeddha, N. P., Paulus, S., Kohlfürst, D. S., Emonts, M., Zenz, W., Carrol, E. D., De Groot, R., Schlapbach, L., Martinon-Torres, F., Bojang, K., Levin, M., Van Der Flier, M. and Anderson, S. T. (2019). Bacteremia in childhood life-threatening infections in Urban Gambia: EUCLIDS in West Africa. Open Forum Infectious Diseases, 6 (9) ofz332, ofz332. doi: 10.1093/ofid/ofz332
Schlapbach, Luregn J., Horton, Stephen Brian, Long, Debbie Amanda, Beca, John, Erickson, Simon, Festa, Marino, d’Udekem, Yves, Alphonso, Nelson, Winlaw, David, Johnson, Kerry, Delzoppo, Carmel, van Loon, Kim, Gannon, B., Fooken, Jonas, Blumenthal, Antje, Young, Paul, Jones, Mark, Butt, Warwick and Schibler, Andreas (2019). Study protocol: NITric oxide during cardiopulmonary bypass to improve Recovery in Infants with Congenital heart defects (NITRIC trial): a randomised controlled trial. BMJ Open, 9 (8) e026664, e026664. doi: 10.1136/bmjopen-2018-026664
Farrell, Deborah, MacLaren, Graeme and Schlapbach, Luregn J. (2019). Infections on extracorporeal life support in adults and children-a survey of international practice on prevention, diagnosis, and treatment. Pediatric Critical Care Medicine, 20 (7), 667-671. doi: 10.1097/PCC.0000000000001941
Schults, Jessica A., Long, Debbie, Pearson, Kylie, Takashima, Mari, Baveas, Thimitra, Schlapbach, Luregn J., Macfarlane, Fiona and Ullman, Amanda J. (2019). Insertion, management, and complications associated with arterial catheters in paediatric intensive care: a clinical audit. Australian Critical Care, 33 (4), 326-332. doi: 10.1016/j.aucc.2019.05.003
Borghini, Lisa, Png, Eileen, Binder, Alexander, Wright, Victoria J., Pinnock, Ellie, de Groot, Ronald, Hazelzet, Jan, Emonts, Marieke, Van der Flier, Michiel, Schlapbach, Luregn J., Anderson, Suzanne, Secka, Fatou, Salas, Antonio, Fink, Colin, Carrol, Enitan D., Pollard, Andrew J., Coin, Lachlan J., Kuijpers, Taco W., Martinon-Torres, Federico, Zenz, Werner, Levin, Michael, Hibberd, Martin L., Davila, Sonia and EUCLIDS consortium (2019). Identification of regulatory variants associated with genetic susceptibility to meningococcal disease. Scientific Reports, 9 (1) 6966, 6966. doi: 10.1038/s41598-019-43292-6
Harley, Amanda, Latour, Jos and Schlapbach, Luregn J. (2019). The role of parental concerns in the recognition of sepsis in children: A literature review. Frontiers in Pediatrics, 7 (APR) 161, 161. doi: 10.3389/fped.2019.00161
MacLaren, Graeme, Cho, Hwa Jin and Schlapbach, Luregn J. (2019). Transforming data into a crystal ball-predicting outcomes after extracorporeal membrane oxygenation. Pediatric Critical Care Medicine, 20 (5), 490-491. doi: 10.1097/PCC.0000000000001910
Schlapbach, Luregn J., Gelbart, Ben, Gelbart, Ben, Festa, Marino, The Australian & New Zealand Intensive Care Society Paediatric Study Group (ANZICS PSG), Kanthimathinathan, Hari Krishnan, Peters, M. J. and Long, Debbie (2019). Global paediatric critical care research: mind the gaps. Intensive Care Medicine, 45 (5), 753-754. doi: 10.1007/s00134-019-05571-8
Schlapbach, Luregn J., Weiss, Scott L. and Wolf, Joshua (2019). Reducing collateral damage from mandates for time to antibiotics in pediatric sepsis - primum non nocere. JAMA Pediatrics, 173 (5), E1-E2. doi: 10.1001/jamapediatrics.2019.0174
Schlapbach, Luregn J. and Argent, Andrew (2019). Applying Sepsis-3 criteria for septic shock to children-not as shocking as at first sight?*. Pediatric Critical Care Medicine, 20 (3), 299-300. doi: 10.1097/PCC.0000000000001884
George, Shane, Humphreys, Susan, Williams, Tara, Gelbart, Ben, Chavan, Arjun, Rasmussen, Katie, Ganeshalingham, Anusha, Erickson, Simon, Ganu, Subodh Suhas, Singhal, Nitesh, Foster, Kelly, Gannon, Brenda, Gibbons, Kristen, Schlapbach, Luregn J, Festa, Marino, Dalziel, Stuart and Schibler, Andreas (2019). Transnasal humidified rapid insufflation ventilatory exchange in children requiring emergent intubation (Kids THRIVE): a protocol for a randomised controlled trial. BMJ Open, 9 (2) e025997, e025997. doi: 10.1136/bmjopen-2018-025997
McKenna, Ronan, Joseph, Lindsay, Sargent, Philip, May, Meryta, Tozer, Sarah, Bialasiewicz, Seweryn, Heney, Claire, Schlapbach, Luregn J. and Clark, Julia E. (2019). Paediatric intensive care admissions during the 2015-2016 Queensland human parechovirus outbreak: parechovirus intensive care admissions. Journal of Paediatrics and Child Health, 55 (8), 968-974. doi: 10.1111/jpc.14336
Obonyo, Nchafatso Gikenyi, Schlapbach, Luregn Jan and Fraser, John Francis (2019). Sepsis: changing definitions, unchanging treatment. Frontiers in Pediatrics, 6 (JAN) 425, 425. doi: 10.3389/fped.2018.00425
Stark, Zornitza, Nisselle, Amy, McClaren, Belinda, Lynch, Fiona, Best, Stephanie, Long, Janet C., Martyn, Melissa, Patel, Chirag, Schlapbach, Luregn J., Barnett, Christopher, Theda, Christiane, Pinner, Jason, Dinger, Marcel E., Lunke, Sebastian and Gaff, Clara L. (2019). Attitudes of Australian health professionals towards rapid genomic testing in neonatal and paediatric intensive care. European Journal of Human Genetics, 27 (10), 1493-1501. doi: 10.1038/s41431-019-0429-y
Moynihan, Katie M., Barlow, Andrew, Heney, Claire, Clark, Julia E., Schlebusch, Sanmarie and Schlapbach, Luregn J. (2019). Viral respiratory infections diagnosed after PICU admission. Pediatric Critical Care Medicine, 20 (1), E46-E50. doi: 10.1097/PCC.0000000000001757
Moynihan, Katie M., Barlow, Andrew, Nourse, Clare, Heney, Claire, Schlebusch, Sanmarié and Schlapbach, Luregn J. (2018). Severe Mycoplasma Pneumoniae Infection in Children Admitted to Pediatric Intensive Care. The Pediatric infectious disease journal, 37 (12), e336-e338. doi: 10.1097/INF.0000000000002029
Pandya, Nischal R., Alphonso, Nelson, Tu, Quyen, Venugopal, Prem and Schlapbach, Luregn J. (2018). Prolonged postoperative vasoplegia in pediatric patients on chronic angiotensin II blocker treatment. Frontiers in Cardiovascular Medicine, 5 121, 121. doi: 10.3389/fcvm.2018.00121
Dierig, Alexa, Berger, Christoph, Agyeman, Philipp K. A., Bernhard-Stirnemann, Sara, Giannoni, Eric, Stocker, Martin, Posfay-Barbe, Klara M., Niederer-Loher, Anita, Kahlert, Christian R., Donas, Alex, Hasters, Paul, Relly, Christa, Riedel, Thomas, Aebi, Christoph, Schlapbach, Luregn J. and Heininger, Ulrich (2018). Time-to-positivity of blood cultures in children with sepsis. Frontiers in Pediatrics, 6 222, 222. doi: 10.3389/fped.2018.00222
Giannoni, Eric, Agyeman, Philipp K. A., Stocker, Martin, Posfay-Barbe, Klara M., Heininger, Ulrich, Spycher, Ben D., Bernhard-Stirnemann, Sara, Niederer-Loher, Anita, Kahlert, Christian R., Donas, Alex, Leone, Antonio, Hasters, Paul, Relly, Christa, Riedel, Thomas, Kuehni, Claudia, Aebi, Christoph, Berger, Christoph, Schlapbach, Luregn J. and Swiss Pediatric Sepsis Study (2018). Neonatal sepsis of early onset, and hospital-acquired and community-acquired late onset: a prospective population-based cohort study. The Journal of Pediatrics, 201, 106-114.e4. doi: 10.1016/j.jpeds.2018.05.048
Perumal, Gopinath, Marathe, Supreet P., Schlapbach, Luregn J., Morwood, Jim, Venugopal, Prem and Alphonso, Nelson (2018). Postoperative catecholamine resistance following fetal methamphetamine exposure. Asian Cardiovascular & Thoracic Annals, 27 (1), 218492318784740-32. doi: 10.1177/0218492318784740
Schlapbach, Luregn J., Berger, Christoph, Aebi, Christoph and Agyeman, Philipp K.A. (2018). SIRS in the time of sepsis-3: what about the children?. Chest, 153 (6), 1512-1512. doi: 10.1016/j.chest.2018.02.037
Kawasaki, Tatsuya, Shime, Nobuaki, Straney, Lahn, Bellomo, Rinaldo, MacLaren, Graeme, Pilcher, David and Schlapbach, Luregn J. (2018). Paediatric sequential organ failure assessment score (pSOFA): a plea for the world-wide collaboration for consensus. Intensive Care Medicine, 44 (6), 995-997. doi: 10.1007/s00134-018-5188-7
Gelbart, Ben, Schlapbach, Luregn, Ganeshalingham, Anusha, Ganu, Subodh, Erickson, Simon, Oberender, Felix, Hoq, Monsurul, Williams, Gary, George, Shane, Festa, Marino, Paediatric Study Group of the Australian and New Zealand Intensive Care Society and Long, Debbie (2018). Fluid bolus therapy in critically ill children: a survey of practice among paediatric intensive care doctors in Australia and New Zealand. Critical Care and Resuscitation, 20 (2), 131-138.
Martinón-Torres, Federico, Salas, Antonio, Rivero-Calle, Irene, Cebey-López, Miriam, Pardo-Seco, Jacobo, Herberg, Jethro A, Boeddha, Navin P, Klobassa, Daniela S, Secka, Fatou, Paulus, Stephane, de Groot, Ronald, Schlapbach, Luregn J, Driessen, Gertjan J, Anderson, Suzanne T, Emonts, Marieke, Zenz, Werner, Carrol, Enitan D, Van der Flier, Michiel, Levin, Michael, Levin, Michael, Coin, Lachlan, Gormley, Stuart, Hamilton, Shea, Herberg, Jethro, Hourmat, Bernardo, Hoggart, Clive, Kaforou, Myrsini, Sancho-Shimizu, Vanessa, Wright, Victoria ... EUCLIDS Consortium (2018). Life-threatening infections in children in Europe (the EUCLIDS Project): a prospective cohort study. The Lancet Child and Adolescent Health, 2 (6), 404-414. doi: 10.1016/S2352-4642(18)30113-5
Boeddha, Navin P., Schlapbach, Luregn J., Driessen, Gertjan J., Herberg, Jethro A., Rivero-Calle, Irene, Cebey-López, Miriam, Klobassa, Daniela S., Philipsen, Ria, de Groot, Ronald, Inwald, David P., Nadel, Simon, Paulus, Stéphane, Pinnock, Eleanor, Secka, Fatou, Anderson, Suzanne T., Agbeko, Rachel S., Berger, Christoph, Fink, Colin G., Carrol, Enitan D., Zenz, Werner, Levin, Michael, van der Flier, Michiel, Martinón-Torres, Federico, Hazelzet, Jan A., Emonts, Marieke and EUCLIDS consortium (2018). Mortality and morbidity in community-acquired sepsis in European pediatric intensive care units: a prospective cohort study from the European Childhood Life-threatening Infectious Disease Study (EUCLIDS). Critical Care, 22 (1) 143, 143. doi: 10.1186/s13054-018-2052-7
Jansen, Melanie A., Schlapbach, Luregn J. and Irving, Helen (2018). Evaluation of a paediatric clinical ethics service. Journal of Paediatrics and Child Health, 54 (11), 1199-1205. doi: 10.1111/jpc.13933
Leclerc, Francis, Duhamel, Alain, Leteurtre, Stéphane, Straney, Lahn, Bellomo, Rinaldo, MacLaren, Graeme, Pilcher, David and Schlapbach, Luregn J. (2018). Which organ dysfunction scores to use in children with infection?. Intensive Care Medicine, 44 (5), 697-698. doi: 10.1007/s00134-018-5123-y
Franklin, Donna, Babl, Franz E, Schlapbach, Luregn J, Oakley, Ed, Craig, Simon, Neutze, Jocelyn, Furyk, Jeremy, Fraser, John F, Jones, Mark, Whitty, Jennifer A, Dalziel, Stuart R. and Schibler, Andreas (2018). A randomized trial of high-flow oxygen therapy in infants with bronchiolitis. New England Journal of Medicine, 378 (12), 1121-1131. doi: 10.1056/NEJMoa1714855
Fleischmann-Struzek, Carolin, Goldfarb, David M., Schlattmann, Peter, Schlapbach, Luregn J., Reinhart, Konrad and Kissoon, Niranjan (2018). The global burden of paediatric and neonatal sepsis: a systematic review. The Lancet Respiratory Medicine, 6 (3), 223-230. doi: 10.1016/S2213-2600(18)30063-8
Domico, Michele, Ridout, Deborah, MacLaren, Graeme, Barbaro, Ryan, Annich, Gail, Schlapbach, Luregn J. and Brown, Katherine L. (2018). Extracorporeal membrane oxygenation for pertussis: predictors of outcome including pulmonary hypertension and leukodepletion. Pediatric Critical Care Medicine, 19 (3), 254-261. doi: 10.1097/PCC.0000000000001454
Schlapbach, Luregn J. and Kissoon, Niranjan (2018). Defining pediatric sepsis. JAMA Pediatrics, 172 (4), 312-314. doi: 10.1001/jamapediatrics.2017.5208
Buettcher, M., Schlapbach, L. J. and Stocker, M. (2018). Sepsis in children—completely different? Sepsis bei Kindern – alles anders?. Notfall und Rettungsmedizin, 22 (3), 219-225. doi: 10.1007/s10049-018-0506-8
Schlapbach, Luregn J., Straney, Lahn, Bellomo, Rinaldo, MacLaren, Graeme and Pilcher, David (2017). Prognostic accuracy of age-adapted SOFA, SIRS, PELOD-2, and qSOFA for in-hospital mortality among children with suspected infection admitted to the intensive care unit. Intensive Care Medicine, 44 (2), 179-188. doi: 10.1007/s00134-017-5021-8
Maul, Clark P., Franklin, Donna, Williams, Tara, Schlapbach, Luregn and Schibler, Andreas (2017). Nasal high-flow therapy in children: a survey of current practice in Australia. Journal of Paediatrics and Child Health, 53 (10), 1031-1032. doi: 10.1111/jpc.13695
Agyeman, Philipp, Schlapbach, Luregn J., Giannoni, Eric, Stocker, Martin, Posfay-Barbe, Klara M., Heininger, Ulrich, Schindler, Matthias, Korten, Insa, Konetzny, Gabriel, Niederer-Loher, Anita, Kahlert, Christian R., Donas, Alex, Leone, Antonio, Hasters, Paul, Relly, Christa, Baer, Walter, Kuehni, Claudia E., Aebi, Christoph and Berger, Christoph (2017). Epidemiology of blood culture-proven bacterial sepsis in children in Switzerland: a prospective population-based cohort study. The Lancet Child and Adolescent Health, 1 (2), 124-133. doi: 10.1016/S2352-4642(17)30010-X
Stocker, Martin, van Herk, Wendy, el Helou, Salhab, Dutta, Sourabh, Fontana, Matteo S., Schuerman, Frank A. B. A., van den Tooren-de Groot, Rita K., Wieringa, Jantien W., Janota, Jan, van der Meer-Kappelle, Laura H., Moonen, Rob, Sie, Sintha D., de Vries, Esther, Donker, Albertine E., Zimmerman, Urs, Schlapbach, Luregn J., de Mol, Amerik C., Hoffman-Haringsma, Angelique, Roy, Madan, Tomaske, Maren, Kornelisse, Rene F., van Gijsel, Juliette, Visser, Eline G., Willemsen, Sten P. and van Rossum, Annemarie M. C. (2017). Procalcitonin-guided decision making for duration of antibiotic therapy in neonates with suspected early-onset sepsis: a multicentre, randomised controlled trial (NeoPIns). Lancet, 390 (10097), 871-881. doi: 10.1016/S0140-6736(17)31444-7
Kessler, Ulf, Schlapbach, Luregn J., Klimek, Peter and Jakob, Stephan M. (2017). Low L-Ficolin associated with disease severity during sepsis in adult ICU patients. Liver International, 37 (9), 1409-1409. doi: 10.1111/liv.13448
Schlapbach, Luregn J. (2017). Time for sepsis-3 in children?. Pediatric Critical Care Medicine, 18 (8), 805-806. doi: 10.1097/PCC.0000000000001203
Asgari, Samira, Schlapbach, Luregn J., Anchisi, Stéphanie, Hammer, Christian, Bartha, Istvan, Junier, Thomas, Mottet-Osman, Geneviève, Posfay-Barbe, Klara M., Longchamp, David, Stocker, Martin, Cordey, Samuel, Kaiser, Laurent, Riedel, Thomas, Kenna, Tony, Long, Deborah, Schibler, Andreas, Telenti, Amalio, Tapparel, Caroline, McLaren, Paul J., Garcin, Dominique and Fellay, Jacques (2017). Severe viral respiratory infections in children with IFIH1 loss-of-function mutations. Proceedings of the National Academy of Sciences, 114 (31), 8342-8347. doi: 10.1073/pnas.1704259114
Schlapbach, Luregn J., MacLaren, Graeme and Straney, Lahn (2017). Venous vs arterial lactate and 30-day mortality in pediatric sepsis. JAMA Pediatrics, 171 (8), 813-813. doi: 10.1001/jamapediatrics.2017.1598
Schlapbach, Luregn J., Ostrowski, Justyna A. and MacLaren, Graeme (2017). The excess burden of severe sepsis in Indigenous Australian children: can anything be done?. Medical Journal of Australia, 207 (1), 45-46. doi: 10.5694/mja17.00464
Schlapbach, Luregn J., Straney, Lahn, Gelbart, Ben, Alexander, Janet, Franklin, Donna, Beca, John, Whitty, Jennifer A., Ganu, Subodh, Wilkins, Barry, Slater, Anthony, Croston, Elizabeth, Erickson, Simon and Schibler, Andreas (2017). Burden of disease and change in practice in critically ill infants with bronchiolitis. European Respiratory Journal, 49 (6) 1601648, 1601648. doi: 10.1183/13993003.01648-2016
Schlapbach, Luregn J., Javouhey, Etienne and Jansen, Nicolaas J. G. (2017). Paediatric sepsis: old wine in new bottles?. Intensive Care Medicine, 43 (11), 1-4. doi: 10.1007/s00134-017-4800-6
Schlapbach, Luregn J. and MacLaren, Graeme (2017). Targeting Staphylococcus aureus in pediatric surviving sepsis bundles. JAMA Pediatrics, 171 (3), 301-301. doi: 10.1001/jamapediatrics.2016.4675
Moynihan, Katie, Barlow, Andrew, Alphonso, Nelson, Anderson, Ben, Johnson, Janelle, Nourse, Clare, Schlebusch, Sanmarié, Karl, Tom R. and Schlapbach, Luregn J. (2017). Impact of viral respiratory pathogens on outcomes after pediatric cardiac surgery. Pediatric Critical Care Medicine, 18 (3), 219-227. doi: 10.1097/PCC.0000000000001083
Schlapbach, Luregn J., MacLaren, Graeme, Festa, Marino, Alexander, Janet, Erickson, Simon, Beca, John, Slater, Anthony, Schibler, Andreas, Pilcher, David, Millar, Johnny and Straney, Lahn (2017). Prediction of pediatric sepsis mortality within 1 h of intensive care admission. Intensive Care Medicine, 43 (8), 1085-1096. doi: 10.1007/s00134-017-4701-8
Ostrowski, Justyna A., Maclaren, Graeme, Alexander, Janet, Stewart, Penny, Gune, Sheena, Francis, Joshua R., Ganu, Subodh, Festa, Marino, Erickson, Simon J., Straney, Lahn and Schlapbach, Luregn J. (2017). The burden of invasive infections in critically ill indigenous children in Australia. Medical Journal of Australia, 206 (2), 78-84. doi: 10.5694/mja16.00595
Roger, Thierry, Schlapbach, Luregn J., Schneider, Anina, Weier, Manuela, Wellmann, Sven, Marquis, Patrick, Vermijlen, David, Sweep, Fred C. G. J., Leng, Lin, Bucala, Richard, Calandra, Thierry and Giannoni, Eric (2017). Plasma levels of macrophage migration inhibitory factor and d-dopachrome tautomerase show a highly specific profile in early life. Frontiers in Immunology, 8 (JAN) 26, 26. doi: 10.3389/fimmu.2017.00026
Mattke, Adrian C., Prabhu, Sudesh, Clark, Julia, Labrom, Robert, Burns, Hanna and Schlapbach, Luregn J. (2017). Lemierre's syndrome, necrotizing pneumonia and staphylococcal septic shock treated with extracorporeal life support. Sage Open Medical Case Reports, 5, 1-5. doi: 10.1177/2050313X17722726
Morin, Luc, Ray, Samiran, Wilson, Clare, Remy, Solenn, Benissa, Mohamed Rida, Jansen, Nicolaas J. G., Javouhey, Etienne, Peters, Mark J., Kneybar, Martin, De Luca, Daniele, Nadel, Simon, Schlapback, Luregn Jan, Maclaren, Graeme and Tissieres, Pierre (2016). Refractory septic shock in children: a European Society of Paediatric and Neonatal Intensive Care definition. Intensive Care Medicine, 42 (12), 1-10. doi: 10.1007/s00134-016-4574-2
Asgari, Samira, McLaren, Paul J., Peake, Jane, Wong, Melanie, Wong, Richard, Bartha, Istvan, Francis, Joshua R., Abarca, Katia, Gelderman, Kyra A., Agyeman, Philipp, Aebi, Christoph, Berger, Christoph, Fellay, Jacques, Schlapbach, Lurgen J. and Swiss Pediatric Sepsis Study (2016). Corrigendum: exome sequencing reveals primary immunodeficiencies in children with community-acquired Pseudomonas aeruginosa sepsis. Frontiers in immunology, 7 (OCT) 447, 447. doi: 10.3389/fimmu.2016.00447
Asgari, Samari, McLaren, Paul J., Peake, Jane, Wong, Melanie, Wong, Richard, Bartha, Istvan, Francis, Joshua R., Abarca, Katia, Gelderman, Krya A., Agyeman, Philipp, Aebi, Christoph, Berger, Christoph, Fellay, Jacques, Schlapbach, Luregn, J., Posfay-Barbe, Klara, Giannoni, Eric, Wagner, Benedicht P., Heininger, Ulrich, Konetzny, Gabriel, Donas, Alex, Stocker, Martin, Leone, Antonio, Hasters, Paul, Niederer-Loher, Anita, Kahlert, Christian, Baer, Walter and Relly, Christa (2016). Exome sequencing reveals primary immunodeficiencies in children with community-acquired Pseudomonas aeruginosa sepsis. Frontiers in Immunology, 7 (SEP) 357, 357. doi: 10.3389/fimmu.2016.00357
Straney, Lahn, Schibler, Andreas, Ganeshalingham, Anusha, Alexander, Janet, Festa, Marino, Slater, Anthony, Maclaren, Graeme and Schlapbach, Luregn J. (2016). Burden and outcomes of severe pertussis infection in critically ill infants. Pediatric Critical Care Medicine, 17 (8), 735-742. doi: 10.1097/PCC.0000000000000851
Zant, Robert, Stocker, Christian, Schlapbach, Luregn Jan, Mayfield, Sara, Karl, Tom and Schibler, Andreas (2016). Procalcitonin in the early course post pediatric cardiac surgery. Pediatric Critical Care Medicine, 17 (7), 624-629. doi: 10.1097/PCC.0000000000000751
van Herk, Wendy, el Helou, Salhab, Janota, Jan, Hagmann, Cornelia, Klingenberg, Claus, Staub, Eveline, Giannoni, Eric, Tissieres, Pierre, Schlapbach, Luregn J., van Rossum, Annemarie M. C., Pilgrim, Sina B. and Stocker, Martin (2016). Variation in current management of term and late-preterm neonates at risk for early-onset sepsis: an international survey and review of guidelines. Pediatric Infectious Disease Journal, 35 (5), 494-500. doi: 10.1097/INF.0000000000001063
Giannoni, Eric, Berger, Christoph, Stocker, Martin, Agyeman, Philipp, Posfay-Barbe, Klara M., Heininger, Ulrich, Konetzny, Gabriel, Niederer-Loher, Anita, Kahlert, Christian, Donas, Alex, Leone, Antonio, Hasters, Paul, Relly, Christa, Baer, Walter, Aebi, Christoph, Schlapbach, Luregn J. and for the Swiss Pediatric Sepsis Study Group (2016). Incidence and outcome of Group B streptococcal sepsis in infants in Switzerland. Pediatric Infectious Disease Journal, 35 (2), 222-224. doi: 10.1097/INF.0000000000000974
Schlapbach, Luregn J., Giannoni, Eric, Wellmann, Sven, Stocker, Martin, Ammann, Roland A. and Graf, Rolf (2015). Normal values for pancreatic stone protein in different age groups. BMC Anesthesiology, 15 (1) 168, 1-6. doi: 10.1186/s12871-015-0149-y
Franklin, Donna, Dalziel, Stuart, Schlapbach, Luregn J., Babl, Franz E., Oakley, Ed, Craig, Simon S., Furyk, Jeremy S., Neutze, Jocelyn, Sinn, Kam, Whitty, Jennifer A., Gibbons, Kristen, Fraser, John and Schibler, Andreas (2015). Early high flow nasal cannula therapy in bronchiolitis, a prospective randomised control trial (protocol): A Paediatric Acute Respiratory Intervention Study (PARIS). BMC Pediatrics, 15 (1) 183, 183.1-183.8. doi: 10.1186/s12887-015-0501-x
Straney, Lahn D., Schlapbach, Luregn J., Yong, Glenn, Bray, Janet E., Millar, Johnny, Slater, Anthony, Alexander, Janet, Finn, Judith and for the Australian and New Zealand Intensive Care Society Paediatric Study Group (2015). Trends in PICU admission and survival rates in children in Australia and New Zealand following cardiac arrest. Pediatric Critical Care Medicine, 16 (7), 613-620. doi: 10.1097/PCC.0000000000000425
Namachivayam, Siva P., Alexander, Janet, Slater, Anthony, Millar, Johnny, Erickson, Simon, Tibballs, James, Festa, Marino, Ganu, Subodh, Segedin, Liz, Schlapbach, Luregn J., Williams, Gary, Shann, Frank and Butt, Warwick (2015). Five-year survival of children with chronic critical illness in Australia and New Zealand. Critical care medicine, 43 (9), 1978-1985. doi: 10.1097/CCM.0000000000001076
Schlapbach, Luregn J., Straney, Lahn, Alexander, Janet, MacLaren, Graeme, Festa, Marino, Schibler, Andreas and Slater, Anthony (2015). Mortality related to invasive infections, sepsis, and septic shock in critically ill children in Australia and New Zealand, 2002-13: a multicentre retrospective cohort study. The Lancet Infectious Diseases, 15 (1), 46-54. doi: 10.1016/S1473-3099(14)71003-5
Schlapbach, Luregn J., Thiel, Steffen, Aebi, Christoph, Hirt, Andreas, Leibundgut, Kurt, Jensenius, Jens C. and Ammann, Roland A. (2014). Corrigendum to "M-ficolin in children with cancer" [Immunobiology 216, (2011), 633-638] DOI: 10.1016/j.imbio.2010.09.013. Immunobiology, 219 (12), 990-991. doi: 10.1016/j.imbio.2014.10.024
Keizer, M. P., Wouters, D., Schlapbach, L. J. and Kuijpers, T. W. (2014). Restoration of MBL-deficiency: redefining the safety, efficacy and viability of MBL-substitution therapy. Molecular Immunology, 61 (2), 174-184. doi: 10.1016/j.molimm.2014.06.005
Larcombe, P. J., Kapur, N., Fraser, C. J., Coulthard, M. G. and Schlapbach, L. J. (2014). Intrabronchial Administration of Activated Recombinant Factor VII in a Young Child With Diffuse Alveolar Hemorrhage. Pediatric Blood & Cancer, 61 (3), 570-571. doi: 10.1002/pbc.24841
Schlapbach, Luregn J., Schaefer, Jonas, Brady, Ann-Maree, Mayfield, Sara and Schibler, Andreas (2014). High-flow nasal cannula (HFNC) support in interhospital transport of critically ill children. Intensive Care Medicine, 40 (4), 592-599. doi: 10.1007/s00134-014-3226-7
Schlapbach, Luregn J., Ersch, Joerg, Balmer, Christian, Pretre, Rene, Tomaske, Maren, Caduff, Rosmarie, Morwood, Jim, Provenzano, Sylvio and Stocker, Christian (2013). Enteroviral myocarditis in neonates. Journal of Paediatrics and Child Health, 49 (9), E451-E454. doi: 10.1111/jpc.12248
Amman, Roland A., Bodmer, Nicole, Simon, Arne, Agyeman, Philipp, Leibundgut, Kurt, Schlapbach, Luregn J. and Niggli, Felix K. (2013). Serum concentrations of mannan-binding lectin (MBL) and MBL-associated serine protease-2 and the risk of adverse events in pediatric patients with cancer and fever in neutropenia. Journal of the Pediatric Infectious Diseases Society, 2 (2) pit005, 155-161. doi: 10.1093/jpids/pit005
Schlapbach, Luregn J., Graf, Rolf, Woerner, Andreas, Fontana, Matteo, Zimmermann-Baer, Urs, Glauser, David, Giannoni, Eric, Roger, Thierry, Muller, Christoph, Nelle, Mathias and Stocker, Martin (2013). Pancreatic stone protein as a novel marker for neonatal sepsis. Intensive Care Medicine, 39 (4), 754-763. doi: 10.1007/s00134-012-2798-3
Schlapbach, Luregn J., Woerner, Andreas, Thiel, Steffen, Ammann, Roland A., Aebi, Christoph, Nelle, Mathias and Jensenius, Jens C. (2013). Good agreement between capillary and venous sampling for lectin pathway proteins. Immunobiology, 218 (4), 465-469. doi: 10.1016/j.imbio.2012.06.001
Cestari, Igor, Evans-Osses, Ingrid, Schlapbach, Luregn J., de Messias-Reason, Iara and Ramirez, Marcel I. (2013). Mechanisms of complement lectin pathway activation and resistance by trypanosomatid parasites. Molecular Immunology, 53 (4), 328-334. doi: 10.1016/j.molimm.2012.08.015
Schlapbach, Luregn J., Adams, Mark, Proietti, Elena, Aebischer, Maude, Grunt, Sebastian, Borradori-Tolsa, Cristina, Bickle-Graz, Myriam, Bucher, Hans Ulrich, Latal, Beatrice and Natalucci, Giancarlo (2012). Outcome at two years of age in a Swiss national cohort of extremely preterm infants born between 2000 and 2008. Bmc Pediatrics, 12 (1) 198, 198.1-198.12. doi: 10.1186/1471-2431-12-198
Schlapbach, Luregn J., Grips, Martin, Justo, Rob and Karl, Tom (2012). Extracorporeal membrane oxygenation as a bridge to diagnosis in a 20-month old girl with pulmonary hypertension and right ventricular failure. Interactive Cardiovascular and Thoracic Surgery, 15 (6), 1088-1089. doi: 10.1093/icvts/ivs401
Schlapbach, Luregn J., Schibler, Andreas and Jensenius, Jens C. (2012). C1-esterase inhibitor treatment in sepsis-Can we target the right patients?. Critical Care Medicine, 40 (9), 2735-2736. doi: 10.1097/CCM.0b013e318258eb7a
Schlapbach, Luregn J., Kjaer, Troels R., Thiel, Steffen, Mattmann, Maika, Nelle, Mathias, Wagner, Bendicht P., Ammann, Roland A., Aebi, Christoph and Jensenius, Jens C. (2012). M-ficolin concentrations in cord blood are related to circulating phagocytes and to early-onset sepsis. Pediatric Research, 71 (4), 368-374. doi: 10.1038/pr.2011.71
Schlapbach, Luregn J., Thiel, Steffen, Kessler, Ulf, Ammann, Roland A., Aebi, Christoph and Jensenius, Jens C. (2011). Congenital H-ficolin deficiency in premature infants with severe necrotising enterocolitis. Gut, 60 (10), 1438-1439. doi: 10.1136/gut.2010.226027
Schlapbach, L. J., Frey, S., Roger, T., Calandra, T., Nelle, M., Aebi, C. and Giannoni, E. (2011). Umbilical venous concentrations of estradiol in infants with early-onset sepsis and chorioamnionitis. Journal of Neonatal-Perinatal Medicine, 4 (2), 147-154. doi: 10.3233/NPM-2011-2739
Schlapbach, Luregn J., Frey, Stefanie, Bigler, Susanna, Manh-Nhi, Chiem, Aebi, Christoph, Nelle, Mathias and Nuoffer, Jean-Marc (2011). Copeptin concentration in cord blood in infants with early-onset sepsis, chorioamnionitis and perinatal asphyxia. BMC Pediatrics, 11 (1) 38, 38.1-38.8. doi: 10.1186/1471-2431-11-38
Pramana, I. A., Latzin, P., Schlapbach, L. J., Hafen, G., Kuehni, C. E., Nelle, M., Riedel, T. and Frey, U. (2011). Respiratory symptoms in preterm infants: burden of disease in the first year of life. European Journal of Medical Research, 16 (5), 223-230. doi: 10.1186/2047-783X-16-5-223
Schlapbach, Luregn J., Thiel, Steffen, Aebi, Christoph, Hirt, Andreas, Leibundgut, Kurt, Jensenius, Jens C. and Ammann, Roland A. (2011). M-ficolin in children with cancer. Immunobiology, 216 (5), 633-638. doi: 10.1016/j.imbio.2010.09.013
Fischa, Urs P., Zehndera, Aina, Hirta, Andreas, Nigglib, Felix K., Simonc, Arne, Ozsahind, Hulya, Schlapbacha, Luregn J. and Ammanna, Roland A. (2011). Mannan-binding lectin (MBL) and MBL-associated serine protease-2 in children with cancer. Swiss Medical Weekly, 141 (APRIL), w13191. doi: 10.4414/smw.2011.13191
Schlapbach, Luregn Jan, Agyeman, Philipp, Hutter, Damian, Aebi, Christoph, Wagner, Bendicht Peter and Riedel, Thomas (2011). Human metapneumovirus infection as an emerging pathogen causing acute respiratory distress syndrome. Journal of Infectious Diseases, 203 (2), 294-295. doi: 10.1093/infdis/jiq045
Schlapbach, Luregn J., Aebischer, Maude, Adams, Mark, Natalucci, Giancarlo, Bonhoeffer, Jan, Latzin, Philipp, Nelle, Mathias, Bucher, Hans Ulrich, Latal, Beatrice, Swiss Neonatal Network and Follow-Up Group, Zeilinger, G., Capone, A., Glanzmann, R., Weber, P., Steinlin, M., Grunt, S., Bar, W., Keller, E., Killer, Ch., Tolsa, J.-F., Bickle-Graz, M., Pfister, R.E., Huppi, P. S., Borradori-Tolsa, C., Berger, T. M., Schmitt-Mechelke, T., Malzacher, A., Micallef, J. P., Steiner, F. and Arlettaz Mieth, R. (2011). Impact of sepsis on neurodevelopmental outcome in a swiss national cohort of extremely premature infants. Pediatrics, 128 (2), E348-E357. doi: 10.1542/peds.2010-3338
Sallenbach, Seraina, Thiel, Steffen, Aebi, Christoph, Otth, Margrith, Bigler, Susanna, Jensenius, Jens C., Schlapbach, Luregn J. and Ammann, Roland A. (2011). Serum Concentrations Of Lectin-Pathway Components In Healthy Neonates, Children And Adults: Mannan-binding lectin (MBL), M-, L-, and H-ficolin, and MBL-associated serine protease-2 (MASP-2). Pediatric Allergy and Immunology, 22 (4), 424-430. doi: 10.1111/j.1399-3038.2010.01104.x
Schlapbach, Luregn J., Mattmann, Maika, Thiel, Steffen, Boillat, Colette, Otth, Margrith, Nelle, Mathias, Wagner, Bendicht, Jensenius, Jens C. and Aebi, Christoph (2010). Differential role of the lectin pathway of complement activation in susceptibility to neonatal sepsis. Clinical Infectious Diseases, 51 (2), 153-162. doi: 10.1086/653531
Kessler, Ulf, Zacchariou, Zaccharious, Schlapbach, Luregn J. and Berger, Steffen (2010). Author reply. World Journal of Pediatrics, 6 (2), 185-186. doi: 10.1007/s12519-010-0035-0
Schlapbach, Luregn Jan, Riedel, Thomas, Genitsch, Vera, Nelle, Mathias and McDougall, Felicity Jane (2010). Fatal pulmonary embolism in a premature neonate after twin-to-twin transfusion syndrome. Pediatrics, 126 (2), E483-E487. doi: 10.1542/peds.2009-3490
Schlapbach, Luregn J., Ersch, Jörg, Adams, Mark, Bernet, Vera, Bucher, Hans Ulrich and Latal, Beatrice (2010). Impact of chorioamnionitis and preeclampsia on neurodevelopmental outcome in preterm infants below 32 weeks gestational age. Acta Paediatrica, International Journal of Paediatrics, 99 (10), 1504-1509. doi: 10.1111/j.1651-2227.2010.01861.x
Zehnder, Aina, Fisch, Urs, Hirt, Andreas, Niggli, Felix K., Simon, Arne, Ozsahin, Hulya, Schlapbach, Luregn J. and Ammann, Roland A. (2009). Prognosis in pediatric hematologic malignancies is associated with serum concentration of mannose-binding lectin-associated serine protease-2 (MASP-2). Pediatric Blood and Cancer, 53 (1), 53-57. doi: 10.1002/pbc.22028
Schlapbach, Luregn Jan, Pfammatter, Jean-Pierre, Nelle, Mathias and McDougall, Felicity Jane (2009). Cardiomegaly in a premature neonate after venous umbilical catheterization. European Journal of Pediatrics, 168 (1), 107-109. doi: 10.1007/s00431-008-0704-3
Schlapbach, L. J., Aebi, C., Hansen, A. G., Hirt, A., Jensenius, J. C. and Ammann, R. A. (2009). H-ficolin serum concentration and susceptibility to fever and neutropenia in paediatric cancer patients. Clinical and Experimental Immunology, 157 (1), 83-89. doi: 10.1111/j.1365-2249.2009.03957.x
Schlapbach, Luregn J., Kessler, Ulf, Thiel, Steffen, Hansen, Annette G., Nelle, Mathias, Ammann, Roland A., Aebi, Christoph and Jensenius, Jens C. (2009). M-ficolin in the neonatal period: associations with need for mechanical ventilation and mortality in premature infants with necrotising enterocolitis. Molecular Immunology, 46 (13), 2597-2603. doi: 10.1016/j.molimm.2009.05.003
Schlapbach, Luregn Jan, Latzin, Philipp, Regamey, Nicolas, Kuehni, Claudia E., Zwahlen, Marcel, Casaulta, Carmen, Aebi, Christoph and Frey, Urs (2009). Mannose-binding lectin cord blood levels and respiratory symptoms during infancy: A prospective birth cohort study. Pediatric Allergy and Immunology, 20 (3), 219-226. doi: 10.1111/j.1399-3038.2008.00782.x
Schlapbach, Luregn J., Aebi, Christoph, Fisch, Urs, Ammann, Roland A., Otth, Margrith, Bigler, Susanne, Nelle, Mathias, Berger, Steffen and Kessler, Ulf (2008). Higher cord blood levels of mannose-binding lectin-associated serine protease-2 in infants with necrotising enterocolitis. Pediatric Research, 64 (5), 562-566. doi: 10.1203/PDR.0b013e3181841335
Schlapbach L.J., Schutz B., Nuoffer J.-M., Brekenfeld C., Muller G. and Fluri S. (2007). Floppy infant with macrocytic anemia and vegan mother. Praxis, 96 (35), 1309-1314. doi: 10.1024/1661-8157.96.35.1309
Schlapbach, L. J., Aebi, C., Otth, M., Luethy, A. Ridolfi, Leibundgut K., Hirt A. and Ammann R.A. (2007). Serum levels of mannose-binding lectin and the risk of fever in neutropenic pediatric cancer patients. Pediatric Blood and Cancer, 49 (1), 11-16. doi: 10.1002/pbc.21097
Schlapbach L.J., Aebi C., Otth M., Leibundgut K., Hirt A. and Ammann R.A. (2007). Deficiency of mannose-binding lectin-associated serine protease-2 associated with increased risk of fever and neutropenia in pediatric cancer patients. Pediatric Infectious Disease Journal, 26 (11), 989-994. doi: 10.1097/INF.0b013e31811ffe6a
Schlapbach L., Liniger B., Schibli S. and Cholewa D. (2006). A small child with acute abdomen and iron deficiency anemia. Praxis, 95 (22), 913-916. doi: 10.1024/0369-8394.95.22.913
Schlapbach L.J., Sozzo A., Ramelli G. and Bianchetti M.G. (2006). Severe normotensive metabolic alkalosis in a 2-month-old boy with hyperekplexia. Journal of Inherited Metabolic Disease, 29 (1), 238-239. doi: 10.1007/s10545-006-0082-9
Hess C., Klimkait T., Schlapbach L., Del Zenero V., Sadallah S., Horakova E., Balestra G., Werder V., Schaefer C., Battegay M. and Schifferli J.-A. (2002). Association of a pool of HIV-1 with erythrocytes in vivo: A cohort study. Lancet, 359 (9325), 2230-2234. doi: 10.1016/S0140-6736(02)09291-7
Conference Papers
Zimmerman, Jerry, Schlapbach, Luregn, Gibbons, Kristen, Cermelli, Silvia, Coin, Lachlan, Davis, Roy, Irwin, Adam, George, Shane, Navalkar, Krupa, Raman, Sainath, Yager, Thomas and Brandon, Richard (2025). Diagnosing pediatric sepsis with septicyte rapid host gene expression. 2025 Critical Care Congress, Orlando, FL United States, 23-25 February 2025. Philadelphia, PA United States: Lippincott Williams and Wilkins. doi: 10.1097/01.ccm.0001104996.00108.d9
Long, Debbie, Gibbons, K., Dow, B., Best, J., Webb, K.-L., Liley, H., Stocker, C., Thoms, D., Schlapbach, L., Lister, P., Anthony, L., Tyack, Z. and Bora, S. (2024). Collaborative Shared Care Intervention To Improve Pics-p Following Critical Illness In Young Children: A Pilot Randomised Controlled Trial. 12th World Congress on Pediatric Intensive and Critical Care, Cancun, Mexico, 1-5 June 2024. Philadelphia, PA United States: Lippincott Williams & Wilkins. doi: 10.1097/01.pcc.0001086144.20231.09
Cree, Michele, Wallis, S., Schlapbach, L., Roberts, J. and Parker, S. (2024). Does renal replacement therapy (RRT) circuitry remove common antibiotics? An ex-vivo study simulating pediatric treatment. 12th World Congress on Pediatric Intensive and Critical Care, Cancun, Mexico, 1-5 June 2024. Philadelphia, PA United States: Lippincott Williams & Wilkins. doi: 10.1097/01.pcc.0001085192.44125.4e
Cree, Michele, Haisz, E., Wallis, S., Schlapbach, L., Roberts, J. and Parker, S. (2024). Sequestration of common antibiotics onto a pediatric extracorporeal membrane oxygenation (ECMO) circuit? An ex-vivo study. 12th World Congress on Pediatric Intensive and Critical Care, Cancun, Mexico, 1-5 June 2024. Philadelphia, PA United States: Lippincott Williams & Wilkins. doi: 10.1097/01.pcc.0001085588.32445.76
Long, Debbie, Gibbons, K., Horton, S., Johnson, K., Buckley, D., Erickson, S., Festa, M., D’Udekem, Y., Alphonso, N., Lemarsney, R., Winlaw, D., Masterson, K., Van Loon, K., Young, P., Schibler, A., Schlapbach, L. and Butt, W. (2024). Neurodevelopment And Quality Of Life In Infants One Year After Open Heart Surgery For Congenital Heart Defect: A Rct Of Nitric Oxide Via Cardiopulmonary Bypass. 12th World Congress on Pediatric Intensive and Critical Care, Cancun, Mexico, 1-5 June 2024. Philadelphia, PA United States: Lippincott Williams & Wilkins. doi: 10.1097/01.pcc.0001084496.00849.0a
Anthony, Lori, Slater, Anthony, Stocker, Christian, Croston, Elizabeth, Erickson, Simon, Delzoppo, Carmel, Gibbons, Kristen, Masterson, Kate, Namachivayam, Siva, Festa, Marino, Lister, Paula, Egan, Jonathan, Millar, Johnny, Schlapbach, Luregn, Sherring, Claire, Butt, Warwick, Gilchrist, Michelle, Quadir, Ashfaque, Waak, Michaela, Ferguson, Alexandra, Dow, Belinda and Long, Deb (2024). Current perspectives, knowledge, and practices of long-term follow-up care after PICU discharge in Australia and New Zealand. Australian and New Zealand Intensive Care Society/Australian College of Critical Care Nursing Intensive Care Annual Scientific meeting, Brisbane, QLD Australia, 10-12 April 2024. Philadelphia, PA United States: Elsevier. doi: 10.1016/j.aucc.2024.07.057
Tu, Quyen, Won, Hayoung Helen, Sime, Fekade, Wallis, Steven, Raman, Sainath, Stacey, Sonya, Cotta, Menino, Schlapbach, Luregn and Roberts, Jason (2024). The fusion study – Compatibility of antibiotics with commonly used medication infusions in a paediatric intensive care unit. Australian and New Zealand Intensive Care Society/Australian College of Critical Care Nursing Intensive Care Annual Scientific meeting, Brisbane, QLD Australia, 10-12 April 2024. Philadelphia, PA United States: Elsevier. doi: 10.1016/j.aucc.2024.07.037
Cree, Michele, Schlapbach, Luregn, Sumi, Chandra, Wallis, Steve, Roberts, Jason and Parker, Suzanne (2023). Does renal replacement therapy impact the clearance of meropenem, piperacillin, tazobactam and vancomycin in a critically ill child? An ex vivo study. ANZICS/ACCCN Intensive Care Annual Scientific Meeting, Adelaide, SA Australia, 29-31 March 2023. Philadelphia, PA United States: Elsevier. doi: 10.1016/j.aucc.2023.07.020
Cree, Michele, Haisz, Emma, Sumi, Chandra, Wallis, Steve, Schlapbach, Luregn, Roberts, Jason and Parker, Suzanne (2023). Are meropenem, piperacillin, tazobactam and vancomycin sequestered onto a paediatric extracorporeal membrane oxygenation circuit? An ex vivo study. ANZICS/ACCCN Intensive Care Annual Scientific Meeting, Adelaide, SA Australia, 29-31 March 2023. Philadelphia, PA United States: Elsevier. doi: 10.1016/j.aucc.2023.07.023
Gilholm, P., Irwin, A., Lister, P., Harley, A., Raman, S., Schlapbach, L. J. and Gibbons, K. (2022). Identifying clinical symptom profiles for sepsis in children screened for sepsis on admission to the emergency department. 11th Congress of the World Federation of Pediatric Intensive & Critical Care Societies, Online, 12-16 July 2022. Philadelphia, PA United States: Lippincott Williams & Wilkins. doi: 10.1097/01.pcc.0000899876.46317.ec
Schlapbach, L. J., Tomaszewski, W., Ablaza, C., Straney, L., Taylor, C. and Millar, J. (2022). Educational Outcomes Of Childhood Survivors Of Critical Illness – A Population-based Linkage Study. 11th World Congress On Pediatric Intensive And Critical Care, Online, 12-16 July 2022. Philadelphia, PA United States: Lippincott Williams & Wilkins. doi: 10.1097/01.pcc.0000899980.76828.0e
Minogue, Jessicah, Keogh, Samantha, Schlapbach, Luregn and Long, Debbie (2022). Long-term outcomes following paediatric sepsis – A narrative review. ANZICS/ACCCN Intensive Care Annual Scientific Meeting, Sydney, NSW Australia, 27-29 April 2022. Philadelphia, PA United States: Elsevier. doi: 10.1016/j.aucc.2022.08.048
Schlapbach, L. (2018). Time for Sepsis-3 in kids? Prognostic accuracy of age-adapted SOFA, SIRS, PELOD-2, and qS0FA in children with infection. NEW YORK: ELSEVIER SCIENCE INC. doi: 10.1016/j.aucc.2017.12.005
Schlapbach, L. (2018). Time for Sepsis-3 in kids? - Prognostic accuracy of age-adapted SOFA, SIRS, PELOD-2, and qS0FA in children with infection. NEW YORK: ELSEVIER SCIENCE INC. doi: 10.1016/j.aucc.2017.12.026
Schlapbach, Luregn, Straney, Lahn, Gelbart, Ben, Alexander, Janet, Franklin, Donna, Beca, John, Whitty, Jennifer, Ganu, Subodh, Wilkins, Barry, Slater, Anthony, Croston, Elizabeth, Erickson, Simon and Schibler, Andreas (2017). Burden of disease and change in practice in critically ill infants with bronchiolitis in Australia and New Zealand 2002 to 2014. 41st Australian and New Zealand Scientific Meeting on Intensive Care, Perth WA, Australia, 20-22 October 2016. Philadelphia, PA United States: Elsevier. doi: 10.1016/j.aucc.2017.02.067
Schlapbach, L. J., Straney, L., Gelbart, B., Alexander, J., Franklin, D., Beca, J., Whitty, J. A., Ganu, S., Wilkins, B., Croston, E., Erickson, S. and Schibler, A. (2016). Burden of Disease and Change in Practice in Critically Ill Infants with Bronchiolitis in Australia and New Zealand 2002 to 2014. NEW YORK: SPRINGER. doi: 10.1016/j.aucc.2017.02.067
Schlapbach, L. J., Agyeman, P., Giannoni, E., Stocker, M., Posfay-Barbe, K., Heiningere, U., Schindler, M., Kuehni, C., Konetzny, G., Niederer-Loher, A., Kahlert, C., Hasters, P., Relly, C., Baer, W., Aebi, C. and Berger, C. (2016). Severe Sepsis with Bacteremia in Children in Switzerland - Results From the Swiss Pediatric Sepsis Study. NEW YORK: SPRINGER.
Schlapbach, L, Graf, R., Woerner, A., Nelle, M., Stocker, M., Fontana, M., Zimmermann-Baer, U., Glauser, D., Giannoni, E., Roger, T. and Mueller, C. (2012). Pancreatic stone protein as a novel marker for neonatal sepsis. Sepsis 2012, Paris, France, 7-9 November 2012. Springer Nature. doi: 10.1186/cc11765
Sallenbach, S., Thiel. S., Aebi, C., Otth, M., Jensenius, J. C., Schlapbach, L. J. and Ammann, R. A. (2011). Age-specific normal ranges of lectin-pathway components in human serum: mannose-binding lectin (MBL), M-, L-, and H-ficolin, and MBL-associated serine protease-2 (MASP-2).. 23rd International National Complement Workshop, New York, New York, USA, 01-05 August 2010. Kidlington, Oxford, United Kingdom: Pergamon Press. doi: 10.1016/j.molimm.2010.05.069
Schlapbach, L. J., Thiel, S., Mattmann, M., Nelle, M., Wagner, B., Ammann, R. A., Aebi, C. and Jensenius, J. C. (2010). M-ficolin serum concentrations are related to early-onset neonatal sepsis and circulating phagocytes. 23rd International National Complement Workshop, New York Ny, Aug 01-05, 2010. PERGAMON-ELSEVIER SCIENCE LTD. doi: 10.1016/j.molimm.2010.05.031
Schlapbach, L. J., Thiel, S., Aebi, C., Hirt, A., Leibundgut, K., Jensenius, J. C. and Ammann, R. A. (2010). Serum M-ficolin in children with cancer. 23rd International National Complement Workshop, New York Ny, Aug 01-05, 2010. PERGAMON-ELSEVIER SCIENCE LTD. doi: 10.1016/j.molimm.2010.05.241
Schlapbach, L. J., Ammann, R. A., Hansen, A. Gudmann, Hirt, A., Jensenius, J. C. and Aebi, C. (2008). Serum concentration of H-ficolin and the risk of fever and neutropenia in pediatric cancer patients. E M H SWISS MEDICAL PUBLISHERS LTD.
Schlapbach, L. J., Aebi, C., Nelle, M., Ammann, R. A., Berger, S. and Kessler, U. (2008). Elevated cord blood levels of mannose-binding lectin-associated serine protease-2 in infants with necrotising enterocolitis - a case-control study. E M H SWISS MEDICAL PUBLISHERS LTD.
Schlapbach, L. J., Latzin, P., Regamey, N., Kuehni, C. E., Zwahlen, M., Casaulta, C., Aebi, C. and Frey, U. (2007). Mannose-binding Lectin cord blood levels are associated with respiratory symptoms during infancy. E M H SWISS MEDICAL PUBLISHERS LTD.
Thesis
Schlapbach Tribolet, Luregn (2020). Severe infections in critically ill children – from epidemiology to outcome prediction. PhD Thesis, Faculty of Medicine, The University of Queensland. doi: 10.14264/uql.2020.190
Seminar Paper
Mohd Ali, Noor Azizah, Jauncey-Cooke, Jacqueline, Bogossian, Fiona, Schlapbach, Luregn and Chang, Ivy (2017). Ventilator-associated pneumonia and ventilator-associated events in PICU, LCCH. Paediatric Intensive Care, Lady Cilento Children's Hospital, The University of Queensland.