Dr Trish Gilholm

Data Scientist

Child Health Research Centre

p.gilholm@uq.edu.au

Researcher biography

Dr Trish Gilholm is a dedicated data scientist, statistician and early-career researcher within the Children's Intensive Care Research Program, Child Health Research Centre. Her research focuses on the application of advanced statistical methods and machine learning techniques to paediatric critical care. With a PhD in Statistics from Queensland University of Technology, her research focuses on personalised predictive modelling to improve outcomes for critically ill children. Dr Gilholm has made significant contributions through her work on projects that include the evaluation of sepsis screening tools, the use of adaptive designs in paediatric critical care clinical trials, and machine learning models to predict long-term educational and developmental outcomes for PICU survivors.

Dr. Gilholm's work has been recognised with numerous awards, including the Executive Dean Commendation for Outstanding Doctoral Thesis Award and Best Oral Presentation at the 2022 and 2021 Children's Health Research Symposiums. She has published her work in leading journals including Intensive Care Medicine and Pediatric Critical Care Medicine. She is actively involved in mentoring, teaching, and supervision of research students.

Publications

Journal Articles (13)

Conference Paper (1)

Journal Articles

Gilholm, Patricia, Wu, Ken, Le Marsney, Renate and Gibbons, Kristen (2024). Barriers and facilitators to implementing adaptive trial designs in paediatric critical care: an international mixed-methods study. Intensive Care Medicine - Paediatric and Neonatal, 2 (1) 31. doi: 10.1007/s44253-024-00054-1

Le Marsney, Renate, Johnson, Kerry, Chumbes Flores, Jenipher, Coetzer, Shelley, Darvas, Jennifer, Delzoppo, Carmel, Jolly, Arielle, Masterson, Kate, Sherring, Claire, Thomson, Hannah, Ergetu, Endrias, Gilholm, Patricia and Gibbons, Kristen S (2024). Assessing the impact of risk-based data monitoring on outcomes for a paediatric multicentre randomised controlled trial. Clinical Trials, 21 (4), 17407745231222019-469. doi: 10.1177/17407745231222019

Long, Debbie A., Gilholm, Patricia, Le Brocque, Robyne, Kenardy, Justin, Gibbons, Kristen and Dow, Belinda L. (2024). Post-traumatic stress and health-related quality of life after admission to paediatric intensive care: Longitudinal associations in mother–child dyads. Australian Critical Care, 37 (1), 98-105. doi: 10.1016/j.aucc.2023.10.004

Gilholm, Patricia, Ergetu, Endrias, Gelbart, Ben, Raman, Sainath, Festa, Marino, Schlapbach, Luregn J., Long, Debbie, Gibbons, Kristen S. and on behalf of the Australian and New Zealand Intensive Care Society Paediatric Study Group (2023). Adaptive clinical trials in pediatric critical care: a systematic review. Pediatric Critical Care Medicine, 24 (9), 738-749. doi: 10.1097/pcc.0000000000003273

Gilholm, Patricia, Gibbons, Kristen, Brüningk, Sarah, Klatt, Juliane, Vaithianathan, Rhema, Long, Debbie, Millar, Johnny, Tomaszewski, Wojtek, Schlapbach, Luregn J., Ganeshalingam, Anusha, Sherring, Claire, Erickson, Simon, Barr, Samantha, Raman, Sainath, Long, Debbie, Schlapbach, Luregn, Gibbons, Kristen, George, Shane, Singh, Puneet, Smith, Vicky, Butt, Warwick, Delzoppo, Carmel, Millar, Johnny, Gelbart, Ben, Oberender, Felix, Ganu, Subodh, Letton, Georgia, Festa, Marino, Harper, Gail and the Australian and New Zealand Intensive Care Society (ANZICS) Centre for Outcomes & Resource Evaluation (CORE) and ANZICS Paediatric Study Group (ANZICS PSG) (2023). Machine learning to predict poor school performance in paediatric survivors of intensive care: a population-based cohort study. Intensive Care Medicine, 49 (7), 785-795. doi: 10.1007/s00134-023-07137-1

Sever, Zoe, Schlapbach, Luregn J., Gilholm, Patricia, Jessup, Melanie, Phillips, Natalie, George, Shane, Gibbons, Kristen and Harley, Amanda (2023). Impact of parental and healthcare professional concern on the diagnosis of pediatric sepsis: a diagnostic accuracy study. Frontiers in Pediatrics, 11 1140121, 1140121. doi: 10.3389/fped.2023.1140121

Gilholm, Patricia, Gibbons, Kristen, Lister, Paula, Harley, Amanda, Irwin, Adam, Raman, Sainath, Rice, Michael, Schlapbach, Luregn J. and Queensland Statewide Sepsis Collaborative (2023). Validation of a paediatric sepsis screening tool to identify children with sepsis in the emergency department: a statewide prospective cohort study in Queensland, Australia. BMJ Open, 13 (1) e061431, 1-25. doi: 10.1136/bmjopen-2022-061431

Morin, Luc, Hall, Mark, de Souza, Daniela, Guoping, Lu, Jabornisky, Roberto, Shime, Nobuaki, Ranjit, Suchitra, Gilholm, Patricia, Nakagawa, Satoshi, Zimmerman, Jerry J., Sorce, Lauren R., Argent, Andrew, Kissoon, Niranjan, Tissières, Pierre, Watson, R. Scott and Schlapbach, Luregn J (2022). The current and future state of pediatric sepsis definitions: an international survey. Pediatrics, 149 (6) ARTN e2021052565. doi: 10.1542/peds.2021-052565

Harley, Amanda, Lister, Paula, Gilholm, Patricia, Rice, Michael, Venkatesh, Bala, Johnston, Amy N.B., Massey, Debbie, Irwin, Adam, Gibbons, Kristen and Schlapbach, Luregn J. (2021). Queensland Pediatric Sepsis Breakthrough Collaborative: Multicenter Observational Study to Evaluate the Implementation of a Pediatric Sepsis Pathway Within the Emergency Department. Critical Care Explorations, 3 (11) e0573, 1-14. doi: 10.1097/cce.0000000000000573

Harley, Amanda, Schlapbach, Luregn J., Lister, Paula, Massey, Debbie, Gilholm, Patricia and Johnston, Amy N. B. (2021). Knowledge translation following the implementation of a state-wide Paediatric Sepsis Pathway in the emergency department- a multi-centre survey study. BMC Health Services Research, 21 (1) 1161, 1161. doi: 10.1186/s12913-021-07128-2

Gilholm, Patricia, Mengersen, Kerrie and Thompson, Helen (2021). Bayesian hierarchical multidimensional item response modeling of small sample, sparse data for personalized developmental surveillance. Educational and Psychological Measurement, 81 (5) ARTN 0013164420987582, 936-956. doi: 10.1177/0013164420987582

Gilholm, Patricia, Mengersen, Kerrie and Thompson, Helen (2020). Identifying latent subgroups of children with developmental delay using Bayesian sequential updating and Dirichlet process mixture modelling. PLoS One, 15 (6) e0233542, 1-17. doi: 10.1371/journal.pone.0233542

Vermande, Marjolijn M., Gilholm, Patricia A., Reijntjes, Albert H. A., Hessen, Dave J., Sterck, Elisabeth H. M. and Overduin-de Vries, Anne M. (2018). Is inspiring group members an effective predictor of social dominance in early adolescence? direct and moderated effects of behavioral strategies, social skills, and gender on resource control and popularity. Journal of Youth and Adolescence, 47 (9), 1813-1829. doi: 10.1007/s10964-018-0830-9

Conference Paper

Gilholm, P., Irwin, A., Lister, P., Harley, A., Raman, S., Schlapbach, L. J. and Gibbons, K. (2022). Identifying clinical symptom profiles for sepsis in children screened for sepsis on admission to the emergency department. 11th Congress of the World Federation of Pediatric Intensive & Critical Care Societies, Online, 12-16 July 2022. Philadelphia, PA United States: Lippincott Williams & Wilkins. doi: 10.1097/01.pcc.0000899876.46317.ec