Dr Ayaho Yamamoto

Postdoctoral Research Fellow

Child Health Research Centre

a.ayaho@uq.edu.au

Researcher biography

Dr. Ayaho Yamamoto is the Group Leader of Laboratory Science at the Children's Health and Environmental Program and is a research fellow in the field of Biomedical Science. Her research focuses on understanding the mechanistic links between environmental exposures and adverse respiratory outcomes. In particular, focuses on the cellular responses following air pollution exposure and/or viral infection on human respiratory epithelium, and the age differences in immune defence mechanisms. Investigate on early intervention strategies with dietary antioxidants to improve respiratory health and reduce the risk of long-term chronic diseases.

Dr. Yamamoto has a Bachelor of Science in Environmental Health and Public Health; her research focused on childhood asthma. She has a Master of Science in Biomedical Science and Pharmacology; the research focus was to understand the mechanisms and to test new drugs for osteoporosis and chondrosarcomas metastasis. She has worked in a Uni-based start-up company for drug development.

Publications

Journal Articles (7)

Conference Papers (5)

Thesis (1)

Journal Articles

Yamamoto, Ayaho, Sly, Peter D., Chew, Keng Yih, Khachatryan, Lavrent, Begum, Nelufa, Yeo, Abrey J., Vu, Luan D, Short, Kirsty R., Cormier, Stephania A and Fantino, Emmanuelle (2023). Environmentally persistent free radicals enhance SARS-CoV-2 replication in respiratory epithelium. Experimental Biology and Medicine, 248 (3), 271-279. doi: 10.1177/15353702221142616

Yamamoto, Ayaho, Sly, Peter D., Begum, Nelufa, Yeo, Abrey J. and Fantino, Emmanuelle (2022). Resveratrol and astaxanthin protect primary human nasal epithelial cells cultured at an air-liquid interface from an acute oxidant exposure. Journal of Cellular Signaling, 3 (4), 207-217. doi: 10.33696/Signaling.3.084

Yamamoto, Ayaho, Sly, Peter D., Henningham, Anna, Begum, Nelufa, Yeo, Abrey J. and Fantino, Emmanuelle (2022). Redox homeostasis in well-differentiated primary human nasal epithelial cells. Journal of Cellular Signaling, 3 (4), 193-206. doi: 10.33696/Signaling.3.083

Zhu, Yanshan, Chew, Keng Yih, Wu, Melanie, Karawita, Anjana C., McCallum, Georgina, Steele, Lauren E., Yamamoto, Ayaho, Labzin, Larisa I., Yarlagadda, Tejasri, Khromykh, Alexander A., Wang, Xiaohui, Sng, Julian D. J., Stocks, Claudia J., Xia, Yao, Kollmann, Tobias R., Martino, David, Joensuu, Merja, Meunier, Frédéric A., Balistreri, Giuseppe, Bielefeldt-Ohmann, Helle, Bowen, Asha C., Kicic, Anthony, Sly, Peter D., Spann, Kirsten M. and Short, Kirsty R. (2022). Ancestral SARS-CoV-2, but not Omicron, replicates less efficiently in primary pediatric nasal epithelial cells. PLoS Biology, 20 (8) e3001728, 1-19. doi: 10.1371/journal.pbio.3001728

Cormier, Stephania A., Yamamoto, Ayaho, Short, Kirsty R., Vu, Luan and Suk, William A. (2022). Environmental impacts on COVID-19: mechanisms of increased susceptibility. Annals of Global Health, 88 (1) 94, 1-7. doi: 10.5334/aogh.3907

Chao, Chia‐Chia, Lee, Wei‐Fang, Wang, Shih‐Wei, Chen, Po‐Chun, Yamamoto, Ayaho, Chang, Tsung‐Ming, Weng, Shun‐Long and Liu, Ju‐Fang (2021). CXC chemokine ligand‐13 promotes metastasis via CXCR5‐dependent signaling pathway in non‐small cell lung cancer. Journal of Cellular and Molecular Medicine, 25 (19), 9128-9140. doi: 10.1111/jcmm.16743

Tang, Chih-Hsin, Yamamoto, Ayaho, Lin, Yuh-Tzy, Fong, Yi-Chin and Tan, Tzu-Wei (2010). Involvement of matrix metalloproteinase-3 in CCL5/CCR5 pathway of chondrosarcomas metastasis. Biochemical Pharmacology, 79 (2), 209-217. doi: 10.1016/j.bcp.2009.08.006

Conference Papers

Yamamoto, A., Sly, P. D., Khachatryan, L., Yeo, A. J., Cormier, S. A. and Fantino, E. (2023). Environmentally persistent free radicals modify oxidative stress related gene expression in well-differentiated human nasal epithelium. American Thoracic Society 2023 International Conference, Washington, DC USA, 19-24 May 2023. Washington, DC USA: American Thoracic Society. doi: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a5682

Yamamoto, Ayaho, Sly, Peter, Chew, Keng, Yeo, Abrey, Short, Kirsty and Fantino, Emmanuelle (2023). Astaxanthin protect against severe acute respiratory syndrome coronavirus 2 infection on well-differentiated primary human nasal epithelial cells. 26th Congress of the Asian Pacific Society of Respirology Above and Beyond, Seoul, Korea, 17–20 November 2022. Richmond, VIC, Australia: John Wiley & Sons. doi: 10.1111/resp.14433

Yamamoto, A., Yeo, A. J., Sly, P. D., Cormier, S. A., Lomnicki, S., Khachatryan, L. and Fantino, E. (2021). The effect of combustion generated environmentally persistent free radicals on well-differentiated human airway epithelial cells. American Thoracic Society 2021 International Conference, Virtual, 14-19 May 2021. New York, NY USA: American Thoracic Society. doi: 10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a4289

Yamamoto, A., Yeo, A. J., Deane, A., Sly, P. D. and Fantino, E. (2020). The effect of oxidative stress on human airway epithelial cells. International Conference of the American-Thoracic-Society, Electr Network, 2020. New York, NY, United States: American Thoracic Society. doi: 10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a2304

Yamamoto, A., Henningham, A., Sly, P. and Fantino, E. (2019). Cellular senscence in differentiated human primary nasal epithelial cells. TSANZSRS 2019 The Australia & New Zealand Society of Respiratory Science and The Thoracic Society of Australia and New Zealand (ANZSRS/TSANZ) Annual Scientific Meeting, Gold Coast, Australia, 29 March–2 April 2019. Richmond, VIC, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/resp.13492

Thesis

Yamamoto, Ayaho (2022). The airway epithelium: oxidative stress and environment. PhD Thesis, Faculty of Medicine, The University of Queensland. doi: 10.14264/d83007f