Journal Articles
Schlapbach, Luregn J., Ganesamoorthy, Devika, Wilson, Clare, Raman, Sainath, George, Shane, Snelling, Peter J., Phillips, Natalie, Irwin, Adam, Sharp, Natalie, Le Marsney, Renate, Chavan, Arjun, Hempenstall, Allison, Bialasiewicz, Seweryn, MacDonald, Anna D., Grimwood, Keith, Cling, Jessica C., McPherson, Stephen J., Blumenthal, Antje, Kaforou, Myrsini, Levin, Michael, Herberg, Jethro A., Gibbons, Kristen S., Coin, Lachlan J. M., EUCLIDS consortium and RAPIDS Study Group (2024). Host gene expression signatures to identify infection type and organ dysfunction in children evaluated for sepsis: a multicentre cohort study. The Lancet Child and Adolescent Health, 8 (5), 325-338. doi: 10.1016/S2352-4642(24)00017-8
Chai, Gene G., Tu, Quyen, Cotta, Menino O., Bauer, Michelle J., Balch, Ross, Okafor, Charles, Comans, Tracy, Kruger, Peter, Meyer, Jason, Shekar, Kiran, Brady, Kara, Fourie, Cheryl, Sharp, Natalie, Vlad, Luminita, Whiley, David, Ungerer, Jacobus P. J., McWhinney, Brett C., Farkas, Andras, Paterson, David L., Clark, Julia E., Hajkowicz, Krispin, Raman, Sainath, Bialasiewicz, Seweryn, Lipman, Jeffrey, Forde, Brian M., Harris, Patrick N. A., Schlapbach, Luregn J., Coin, Lachlan, Roberts, Jason A. and Irwin, Adam D. (2024). Achievement of therapeutic antibiotic exposures using Bayesian dosing software in critically unwell children and adults with sepsis. Intensive Care Medicine, 50 (4), 1-9. doi: 10.1007/s00134-024-07353-3
McWhinney, Brett, Ungerer, Jacobus, LeMarsey, Renate, Phillips, Natalie, Raman, Sainath, Gibbons, Kristen, Schlapbach, Luregn J. and on behalf of Rapid Acute Paediatric Infection Diagnosis in Suspected Sepsis (RAPIDS) Study Investigators (2024). Serum levels of vitamin C and thiamin in children with suspected sepsis: a prospective observational cohort study. Pediatric Critical Care Medicine, 25 (2), 171-176. doi: 10.1097/PCC.0000000000003349
Harley, Amanda, George, Shane, Phillips, Natalie, King, Megan, Long, Debbie, Keijzers, Gerben, Lister, Paula, Raman, Sainath, Bellomo, Rinaldo, Gibbons, Kristen, Schlapbach, Luregn J. and on behalf of Resuscitation in Paediatric Sepsis Randomized Controlled Pilot Platform Study in the Emergency Department (RESPOND ED) Study Group (2024). Resuscitation with early adrenaline infusion for children with septic shock: a randomized pilot trial. Pediatric Critical Care Medicine, 25 (2), 106-117. doi: 10.1097/PCC.0000000000003351
Schlapbach, Luregn J., Raman, Sainath, Buckley, David, George, Shane, King, Megan, Ridolfi, Roberta, Harley, Amanda, Cree, Michele, Long, Debbie, Erickson, Simon, Singh, Puneet, Festa, Marino, Gibbons, Kristen, Bellomo, Rinaldo and on behalf of Resuscitation in Paediatric Sepsis Randomized Controlled Pilot Platform in the Paediatric Intensive Care Unit (RESPOND PICU) Study Investigators and the Australian and New Zealand Intensive Care Society Paediatric Study Group (2024). Resuscitation with vitamin C, hydrocortisone, and thiamin in children with septic shock: a multicenter randomized pilot study. Pediatric Critical Care Medicine, 25 (2), 159-170. doi: 10.1097/PCC.0000000000003346
Harris, Patrick N. A., Bauer, Michelle J., Lüftinger, Lukas, Beisken, Stephan, Forde, Brian M., Balch, Ross, Cotta, Menino, Schlapbach, Luregn, Raman, Sainath, Shekar, Kiran, Kruger, Peter, Lipman, Jeff, Bialasiewicz, Seweryn, Coin, Lachlan, Roberts, Jason A., Paterson, David L. and Irwin, Adam D. (2024). Rapid nanopore sequencing and predictive susceptibility testing of positive blood cultures from intensive care patients with sepsis. Microbiology spectrum, 12 (2) e0306523, e0306523. doi: 10.1128/spectrum.03065-23
Schults, Jessica A., Charles, Karina R., Harnischfeger, Jane, Ware, Robert S., Royle, Ruth H., Byrnes, Joshua M., Long, Debbie A., Ullman, Amanda J., Raman, Sainath, Waak, Michaela, Lake, Anna, Cooke, Marie, Irwin, Adam, Tume, Lyvonne and Hall, Lisa (2023). Implementing paediatric appropriate use criteria for endotracheal suction to reduce complications in mechanically ventilated children with respiratory infections. Australian Critical Care, 37 (1), 1-9. doi: 10.1016/j.aucc.2023.09.008
Obonyo, Nchafatso G., Sela, Declan P., Raman, Sainath, Rachakonda, Reema, Schneider, Bailey, Hoe, Louise E. See, Fanning, Jonathon P., Bassi, Gianluigi Li, Maitland, Kathryn, Suen, Jacky Y. and Fraser, John F. (2023). Resuscitation-associated endotheliopathy (RAsE): a conceptual framework based on a systematic review and meta-analysis. Systematic Reviews, 12 (1) 221, 221. doi: 10.1186/s13643-023-02385-0
Raman, Sainath, Rahiman, Sarfaraz, Kennedy, Melanie, Mattke, Adrian, Venugopal, Prem, McBride, Craig, Tu, Quyen, Zapf, Florian, Kuhlwein, Eva, Woodgate, Jemma, Singh, Puneet, Schlapbach, Luregn J. and Gibbons, Kristen S. (2023). REstrictive versus StandarD FlUid Management in Mechanically Ventilated ChildrEn Admitted to PICU: study protocol for a pilot randomised controlled trial (REDUCE-1). BMJ Open, 13 (11) e076460, 1-8. doi: 10.1136/bmjopen-2023-076460
Gilholm, Patricia, Ergetu, Endrias, Gelbart, Ben, Raman, Sainath, Festa, Marino, Schlapbach, Luregn J., Long, Debbie, Gibbons, Kristen S. and on behalf of the Australian and New Zealand Intensive Care Society Paediatric Study Group (2023). Adaptive clinical trials in pediatric critical care: a systematic review. Pediatric Critical Care Medicine, 24 (9), 738-749. doi: 10.1097/pcc.0000000000003273
Long, Debbie, Anderson, Vicki A., Crossley, Louise, Sood, Nikita Tuli, Charles, Karina R., MacDonald, Anna D., Bora, Samudragupta, Pestell, Carmela F., Murrell, Kathryn, Pride, Natalie A., Anderson, Peter J., Badawi, Nadia, Rose, Brian, Baillie, Heidi, Masterson, Kate, Chumbes Flores, Jenipher, Sherring, Claire, Raman, Sainath, Beca, John, Erickson, Simon, Festa, Marino, Anderson, Benjamin W., Venugopal, Prem, Yim, Deane, Andrews, David, Cheung, Michael, Brizard, Christian, Gentles, Thomas L., Iyengar, Ajay ... Gibbons, Kristen S. (2023). Longitudinal cohort study investigating neurodevelopmental and socioemotional outcomes in school-entry aged children after open heart surgery in Australia and New Zealand: the NITRIC follow-up study protocol. BMJ Open, 13 (8) e075429, e075429. doi: 10.1136/bmjopen-2023-075429
Kayumov, Mukhammad, Kim, Dowan, Raman, Sainath, MacLaren, Graeme, Jeong, In Seok and Cho, Hwa Jin (2023). Author Correction: Combined effects of sepsis and extracorporeal membrane oxygenation on left ventricular performance in a murine model. Scientific Reports, 13 (1) 1049, 1-1. doi: 10.1038/s41598-023-28375-9
Obonyo, Nchafatso G., Sela, Declan P., Raman, Sainath, Rachakonda, Reema, Schneider, Bailey, Hoe, Louise E. See, Fanning, Jonathon P., Bassi, Gianluigi Li, Maitland, Kathryn, Suen, Jacky Y. and Fraser, John F. (2023). Resuscitation Associated Endotheliopathy (PubMed). searchRxiv, 2023. doi: 10.1079/searchrxiv.2023.00206
Gilholm, Patricia, Gibbons, Kristen, Lister, Paula, Harley, Amanda, Irwin, Adam, Raman, Sainath, Rice, Michael, Schlapbach, Luregn J. and Queensland Statewide Sepsis Collaborative (2023). Validation of a paediatric sepsis screening tool to identify children with sepsis in the emergency department: a statewide prospective cohort study in Queensland, Australia. BMJ Open, 13 (1) e061431, 1-25. doi: 10.1136/bmjopen-2022-061431
Raman, Sainath, Gibbons, Kristen S., Mattke, Adrian, Schibler, Andreas, Trnka, Peter, Kennedy, Melanie, Le Marsney, Renate and Schlapbach, Luregn J. (2022). Effect of Saline vs gluconate/acetate–buffered solution vs lactate-buffered solution on serum chloride among children in the pediatric Intensive Care Unit: the SPLYT-P randomized clinical trial. JAMA Pediatrics, 177 (2), 122-131. doi: 10.1001/jamapediatrics.2022.4912
Kayumov, Mukhammad, Kim, Dowan, Raman, Sainath, MacLaren, Graeme, Jeong, In Seok and Cho, Hwa Jin (2022). Combined effects of sepsis and extracorporeal membrane oxygenation on left ventricular performance in a murine model. Scientific Reports, 12 (1) 22181, 1-8. doi: 10.1038/s41598-022-26145-7
Joshi, R. S., Wiemers, M., Zahir, S. F. and Raman, S. (2022). PP286 [Medical Workforce & Education » Staff well being /health (Stress, burnout, moral distress, spirituality)]: IMPACT OF A MINDFULNESS-BASED PROGRAM (MBP) ON PAEDATRIC INTENSIVE CARE STAFF WELLBEING. Pediatric Critical Care Medicine, 23 (Supplement 1 11S). doi: 10.1097/01.pcc.0000900952.25047.fd
Blythe, Robin, Lister, Paula, Seaton, Robert, Harley, Amanda, Schlapbach, Luregn J., McPhail, Steven, Venkatesh, Bala, Irwin, Adam, Raman, Sainath, Schlapbach, Luregn, Harley, Amanda, Irwin, Adam, Graham, Nicolette, Thomson, Fiona, Owen, Kieran, Garrish, Kirsten, Sampson, Emma, Long, Debbie, George, Shane, Grimwood, Keith, Bell, Christa, Semple, Bethany, Adams, Claire, Brown, Josea, Maloney, Louise, Lister, Paula, Schofield, Scott, Thomas, Clare, Dejong, Liam ... the Queensland State-wide Sepsis Collaborative (2022). Patient and economic impact of implementing a paediatric sepsis pathway in emergency departments in Queensland, Australia. Scientific Reports, 12 (1) 10113, 10113. doi: 10.1038/s41598-022-14226-6
Raman, Sainath, English, Alana, O'Keefe, Meagan, Harley, Amanda, Steele, Mary, Minogue, Jess, Weller, Kate, Long, Debbie, Irwin, Adam and Lister, Paula (2021). Designing support structures post sepsis in children: perspectives of the Queensland Paediatric Sepsis Program. Frontiers in Pediatrics, 9 759234, 759234. doi: 10.3389/fped.2021.759234
Schlapbach, Luregn J., de Oliveira, Claudio Flauzinho, Raman, Sainath and de Souza, Daniela (2021). Metabolic resuscitation in pediatric sepsis: a narrative review. Translational Pediatrics, 10 (10), 2678-2688. doi: 10.21037/tp-21-1
Tu, Quyen, Cotta, Menino, Raman, Sainath, Graham, Nicolette, Schlapbach, Luregn and Roberts, Jason A (2021). Individualized precision dosing approaches to optimize antimicrobial therapy in pediatric populations. Expert Review of Clinical Pharmacology, 14 (11), 1-17. doi: 10.1080/17512433.2021.1961578
Raman, Sainath, Schibler, Andreas, Le Marsney, Renate, Trnka, Peter, Kennedy, Melanie, Mattke, Adrian, Gibbons, Kristen and Schlapbach, Luregn J. (2021). 0.9% Sodium chloride solution versus Plasma-Lyte 148 versus compound sodium lacTate solution in children admitted to PICU—a randomized controlled trial (SPLYT-P): study protocol for an intravenous fluid therapy trial. Trials, 22 (1) 427. doi: 10.1186/s13063-021-05376-5
Irwin, Adam D., Coin, Lachlan J. M., Harris, Patrick N. A., Cotta, Menino Osbert, Bauer, Michelle J., Buckley, Cameron, Balch, Ross, Kruger, Peter, Meyer, Jason, Shekar, Kiran, Brady, Kara, Fourie, Cheryl, Sharp, Natalie, Vlad, Luminita, Whiley, David, Beatson, Scott A., Forde, Brian M., Paterson, David, Clark, Julia, Hajkowicz, Krispin, Raman, Sainath, Bialasiewicz, Seweryn, Lipman, Jeffrey, Schlapbach, Luregn J. and Roberts, Jason A. (2021). Optimising treatment outcomes for children and adults through rapid genome sequencing of sepsis pathogens. A study protocol for a prospective, multi-centre trial (DIRECT). Frontiers in Cellular and Infection Microbiology, 11 667680, 1-8. doi: 10.3389/fcimb.2021.667680
Raman, Sainath, Brown, Georgia, Long, Debbie, Gelbart, Ben, Delzoppo, Carmel, Millar, Johnny, Erickson, Simon, Festa, Marino, Schlapbach, Luregn J., For the Australian and New Zealand Intensive Care Society Paediatric Study Group (ANZICS PSG) and Gibbons, Kristen (2021). Priorities for paediatric critical care research: a modified Delphi study by the Australian and New Zealand Intensive Care Society Paediatric Study Group. Critical Care and Resuscitation, 23 (2), 194-201. doi: 10.51893/2021.2.oa6
Schlapbach, Luregn J., Gibbons, Kristen, Ridolfi, Roberta, Harley, Amanda, Cree, Michele, Long, Debbie, Buckley, David, Erickson, Simon, Festa, Marino, George, Shane, King, Megan, Singh, Puneet, Raman, Sainath, Bellomo, Rinaldo and The RESPOND PICU study investigators and the Australian New Zealand Intensive Care Society Paediatric Study Group (ANZICS PSG) (2021). Resuscitation in Paediatric Sepsis Using Metabolic Resuscitation–A Randomized Controlled Pilot Study in the Paediatric Intensive Care Unit (RESPOND PICU): Study Protocol and Analysis Plan. Frontiers in Pediatrics, 9 663435, 1-10. doi: 10.3389/fped.2021.663435
James, Tibballs, Sainath, Raman and Peter, Francis (2021). Effects on organ donation of transition from apnoeic-oxygenation to radioisotope brain scanning to diagnose brain death in children. Archives of Organ Transplantation, 1-7. doi: 10.17352/2640-7973.000017
Yanase, Fumitaka, Raman, Sainath, Naorungroj, Thummaporn, McCarthy, Avril, Cree, Michele, Schlapbach, Luregn J and Bellomo, Rinaldo (2021). Efficacy and safety of parenteral high-dose vitamin C therapy in pediatric patients: a scoping review. Pediatric critical care medicine: a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 22 (6), 561-571. doi: 10.1097/PCC.0000000000002686
Heinsar, Silver, Raman, Sainath, Suen, Jacky Y., Cho, Hwa Jin and Fraser, John F. (2021). The use of extracorporeal membrane oxygenation in children with acute fulminant myocarditis. Clinical and Experimental Pediatrics, 64 (5), 188-195. doi: 10.3345/cep.2020.00836
Tai, Chian Wern, Gibbons, Kristen, Schibler, Andreas, Schlapbach, Luregn J. and Raman, Sainath (2021). Acute kidney injury: epidemiology and course in critically ill children. Journal of Nephrology, 35 (2), 559-565. doi: 10.1007/s40620-021-01071-5
Passmore, Margaret R., Ki, Katrina K., Chan, Chris H. H., Lee, Talvin, Bouquet, Mahé, Wood, Emily S., Raman, Sainath, Rozencwajg, Sacha, Burrell, Aidan J. C., McDonald, Charles I., Langguth, Daman, Shekar, Kiran, Malfertheiner, Maximilian V., Fraser, John F. and Suen, Jacky Y. (2020). The effect of hyperoxia on inflammation and platelet responses in an ex vivo extracorporeal membrane oxygenation circuit. Artificial Organs, 44 (12) aor.13771, 1276-1285. doi: 10.1111/aor.13771
Huth, Samuel Fergus, Slater, Anthony, Waak, Michaela, Barlow, Karen Maria and Raman, Sainath (2020). Predicting neurological recovery following traumatic brain injury in children: a systematic review of prognostic models. Journal of Neurotrauma, 37 (20) neu.2020.7158, 2141-2149. doi: 10.1089/neu.2020.7158
Raman, Sainath, Tai, Chian Wern, Le Marsney, Renate, Schibler, Andreas, Gibbons, Kristen and Schlapbach, Luregn J. (2020). Prediction of Acute Kidney Injury on Admission to Pediatric Intensive Care. Pediatric Critical Care Medicine, Publish Ahead of Print (9), 811-819. doi: 10.1097/pcc.0000000000002411
Hussey, Alexander and Raman, Sainath (2020). Catheterisation of the brachial artery in children: should we be so concerned?. Critical Care and Resuscitation, 22 (2), 173-173. doi: 10.51893/2020.2.l2
Glasheen, John, Holmes, Paul, Rampersad, Neeta and Raman, Sainath (2020). Endotracheal intubation by a specialised paediatric retrieval team. Emergency Medicine Australasia, 32 (1), 75-79. doi: 10.1111/1742-6723.13341
Crane, Natalie, Pool, Natasha, Chang, Ivy, Rogan, Sharna, Stocker, Christian and Raman, Sainath (2019). A dedicated paediatric logistic organ dysfunction score - adjusted pressure injury risk assessment scale is required for tertiary paediatric ICUs. Cardiology in the Young, 29 (3), 455-456. doi: 10.1017/s1047951118002251
Raman, Sainath, Ray, Samiran and Peters, Mark J. (2019). Widening Evidence-Base of Risk With Hyperoxia. Pediatric Critical Care Medicine, 20 (1), 99-99. doi: 10.1097/PCC.0000000000001770
Raman, Sainath, Chentouf, Latifa, DeVile, Catherine, Peters, Mark J. and Rahman, Shamima (2018). Near infrared spectroscopy with a vascular occlusion test as a biomarker in children with mitochondrial and other neuro-genetic disorders. PLoS One, 13 (7) e0199756, e0199756. doi: 10.1371/journal.pone.0199756
Jones, Gareth A. L., Ramnarayan, Padmanabhan, Raman, Sainath, Inwald, David, Grocott, Michael P. W., Eaton, Simon, Ray, Samiran, Griksaitis, Michael J., Pappachan, John, Wiley, Daisy, Mouncey, Paul R., Wulff, Jerome, Harrison, David A., Rowan, Kathryn M. and Peters, Mark J. (2017). Protocol for a randomised pilot multiple centre trial of conservative versus liberal oxygenation targets in critically ill children (Oxy-PICU). BMJ Open, 7 (12) e019253, e019253. doi: 10.1136/bmjopen-2017-019253
Ray, Samiran, Brick, Thomas, Raman, Sainath, Birrell, Paul J., Klein, Nigel J. and Peters, Mark J. (2017). Haemodynamic changes with paracetamol in critically-ill children. Journal of Critical Care, 40, 108-112. doi: 10.1016/j.jcrc.2017.03.026
Ray, Samiran, Rogers, Libby, Pagel, Christina, Raman, Sainath, Peters, Mark J. and Ramnarayan, Padmanabhan (2017). Pao(2)/Fio(2) ratio derived from the Spo(2)/Fio(2) ratio to improve mortality prediction using the Pediatric Index of Mortality-3 score in transported intensive care admissions. Pediatric Critical Care Medicine, 18 (3), E131-E136. doi: 10.1097/pcc.0000000000001075
Ray, Samiran, Rogers, L., Raman, S. and Peters, M. J. (2017). Liberal oxygenation in paediatric intensive care: retrospective analysis of high-resolution SpO2 data. Intensive Care Medicine, 43 (1), 146-147. doi: 10.1007/s00134-016-4606-y
Raman, Sainath, Prince, Nicholas J., Hoskote, Aparna, Ray, Samiran and Peters, Mark J. (2016). Admission Pao(2) and mortality in critically ill children: a cohort study and systematic review. Pediatric Critical Care Medicine, 17 (10), E444-E450. doi: 10.1097/pcc.0000000000000905
Greene, Edel, Shokur, Rumeena, Brown, Lisa, Petros, Andy and Raman, Sainath (2016). Incidence of hypermanganesemia in children who are administered parenteral nutrition. Journal of Parenteral and Enteral Nutrition, 40 (6), 766-767. doi: 10.1177/0148607116638046
Raman, Sainath, Ray, Samiran and Peters, Mark J. (2016). Survey of oxygen delivery practices in UK paediatric intensive care units. Critical Care Research and Practice, 2016 6312970, 6312970-4. doi: 10.1155/2016/6312970
Raman, Sainath, Klein, Nigel, Kwan, Antonia, Hubank, Mike, Rahman, Shamima, Rashid, Asrar and Peters, Mark J. (2015). Oxidative phosphorylation gene expression falls at onset and throughout the development of meningococcal sepsis-induced multi-organ failure in children. Intensive Care Medicine, 41 (8), 1489-1490. doi: 10.1007/s00134-015-3817-y
Raman, Sainath and Ramnarayan, Padmanabhan (2014). Impact of stops for road traffic accidents on the inter-hospital transport of critically ill children. Emergency Medicine Journal, 31 (7), 589-590. doi: 10.1136/emermed-2013-202462
Raman, Sainath and Peters, Mark J. (2014). Fluid management in the critically ill child. Pediatric Nephrology, 29 (1), 23-34. doi: 10.1007/s00467-013-2412-0
Raman, Sainath, Desai, Ajay and Halley, Gillian (2009). Application of a clinical transfusion score to pediatric cardiac surgical patients. Pediatric Critical Care Medicine, 10 (6), 701-701. doi: 10.1097/pcc.0b013e3181b7f920
Conference Paper
Gilholm, P., Irwin, A., Lister, P., Harley, A., Raman, S., Schlapbach, L. J. and Gibbons, K. (2022). Identifying clinical symptom profiles for sepsis in children screened for sepsis on admission to the emergency department. 11th Congress of the World Federation of Pediatric Intensive & Critical Care Societies, Online, 12-16 July 2022. Philadelphia, PA United States: Lippincott Williams & Wilkins. doi: 10.1097/01.pcc.0000899876.46317.ec